{
 "built": "2026-09-12",
 "source": "PubMed IDs cited by Orphanet (Orphadata epidemiology) for the site's ORPHAcodes, publications verified on the site, DOIs published on member associations' websites, and a fixed title-level PubMed query on thalidomide embryopathy; metadata from NCBI E-utilities / Crossref",
 "thalidomide_query": "thalidomide[Title] AND (teratogen*[Title] OR embryopath*[Title] OR \"birth defects\"[Title] OR phocomelia[Title] OR survivors[Title] OR \"limb\"[Title] OR malformation*[Title] OR Contergan[Title] OR victims[Title] OR disaster[Title] OR tragedy[Title])",
 "systematic_review_query": "(meta-analysis[pt] OR systematic review[pt] OR \"systematic review\"[ti] OR \"meta-analysis\"[ti]) AND (\"limb reduction\"[tiab] OR \"limb deficiency\"[tiab] OR \"limb deficiencies\"[tiab] OR \"limb difference\"[tiab] OR \"limb differences\"[tiab] OR \"limb defects\"[tiab] OR \"upper limb anomalies\"[tiab] OR \"congenital hand\"[tiab] OR polydactyly[tiab] OR syndactyly[tiab] OR \"Poland syndrome\"[tiab] OR \"Poland sequence\"[tiab] OR symbrachydactyly[tiab] OR brachydactyly[tiab] OR ectrodactyly[tiab] OR \"split hand\"[tiab] OR amelia[tiab] OR phocomelia[tiab] OR hemimelia[tiab] OR \"radial longitudinal deficiency\"[tiab] OR \"radial club hand\"[tiab] OR \"fibular deficiency\"[tiab] OR \"tibial deficiency\"[tiab] OR \"amniotic band\"[tiab] OR \"Adams-Oliver\"[tiab] OR \"Holt-Oram\"[tiab] OR \"thrombocytopenia-absent radius\"[tiab] OR \"thalidomide embryopathy\"[tiab] OR dysmelia[tiab])",
 "entries": [
  {
   "pmid": "41932552",
   "doi": "10.1016/j.taap.2026.117811",
   "title": "Alpha-terpineol induced developmental toxicity in Wistar rats: Embryotoxic, teratogenic, and targeted gene expression effects",
   "authors": [
    "Hegde SS",
    "Malashetty VB"
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "2026",
   "volume": "511",
   "pages": "117811",
   "pubtypes": [],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39679807",
   "doi": "10.1111/ppe.13161",
   "title": "Assessing the Impact of Exposure Misclassification in Case-Control Studies of Self-Reported Medication Use",
   "authors": [
    "Adrien N",
    "MacLehose RF",
    "Werler MM",
    "et al."
   ],
   "journal": "Paediatric and perinatal epidemiology",
   "year": "2026",
   "volume": "40",
   "pages": "190-199",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41641302",
   "doi": "10.1016/j.aed.2025.08.019",
   "title": "Bardet-Biedl Syndrome in Four Siblings: Clinical and Genetic Insights From a Rare Familial Cluster",
   "authors": [
    "Jena D",
    "Pattanaik S",
    "Sahoo SK",
    "et al."
   ],
   "journal": "AACE endocrinology and diabetes",
   "year": "2026",
   "volume": "13",
   "pages": "22-26",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "42404495",
   "doi": "10.1002/hsr2.72655",
   "title": "Clinical and Genetic Spectrum of Filippi Syndrome: A Systematic Review of Published Case Reports and Case Series",
   "authors": [
    "Faheem MA",
    "Ghanghro L",
    "Khan A",
    "et al."
   ],
   "journal": "Health science reports",
   "year": "2026",
   "volume": "9",
   "pages": "e72655",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta",
    "review"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41951339",
   "doi": "10.1136/bmjment-2025-302270",
   "title": "Congenital malformation risk following prenatal antipsychotic exposure: a systematic safety surveillance approach",
   "authors": [
    "Straub L",
    "Wang SV",
    "Hernandez-Diaz S",
    "et al."
   ],
   "journal": "BMJ mental health",
   "year": "2026",
   "volume": "29",
   "pages": "",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41530901",
   "doi": "10.1097/ADM.0000000000001650",
   "title": "Descriptive Exploration of Features Among Infants With Prenatal Fentanyl Exposure in a Multisite Cohort of Maternal-Infant Dyads Affected by Opioid Use Disorder",
   "authors": [
    "Dorsey AN",
    "Rasmussen SA",
    "Cragan JD",
    "et al."
   ],
   "journal": "Journal of addiction medicine",
   "year": "2026",
   "volume": "20",
   "pages": "e4-e11",
   "pubtypes": [
    "Multicenter Study"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41678211",
   "doi": "10.1093/jas/skag040",
   "title": "Effects of wildfire smoke exposure on health parameters and inflammatory responses of beef-on-dairy calves",
   "authors": [
    "Ranches J",
    "Dos Santos ACR",
    "Puerto-Hernandez GM",
    "et al."
   ],
   "journal": "Journal of animal science",
   "year": "2026",
   "volume": "104",
   "pages": "",
   "pubtypes": [],
   "codes": [
    "1027"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "42569392",
   "doi": "10.1080/26941899.2026.2696661",
   "title": "Evaluating Missing Data Imputation Strategies for Environmental Mixture Models: A Simulation Study and Applied Analysis",
   "authors": [
    "Boafo YS",
    "Mostafa S",
    "Obeng-Gyasi E"
   ],
   "journal": "Data science in science",
   "year": "2026",
   "volume": "5",
   "pages": "",
   "pubtypes": [],
   "codes": [
    "1027"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "42370086",
   "doi": "10.1016/j.ero.2025.11.011",
   "title": "Fertility and pregnancy outcomes after CAR T-cell therapy: insights from a systematic review",
   "authors": [
    "Kremer P",
    "Holzer MT",
    "Ruffer N",
    "et al."
   ],
   "journal": "EULAR rheumatology open",
   "year": "2026",
   "volume": "2",
   "pages": "62-68",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta",
    "review"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40498878",
   "doi": "10.1097/PXR.0000000000000441",
   "title": "Functional outcome measures for pediatric upper limb deficiencies with and without prostheses: A systematic review and appraisal",
   "authors": [
    "Cordray H",
    "Fiandeiro M",
    "Banala M",
    "et al."
   ],
   "journal": "Prosthetics and orthotics international",
   "year": "2026",
   "volume": "50",
   "pages": "50-67",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41554827",
   "doi": "10.1038/s41598-026-36527-w",
   "title": "Maternal exposure to ambient air pollution and risk of congenital limb defects in offspring",
   "authors": [
    "Zhang Y",
    "Tan Y",
    "Zhang D",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2026",
   "volume": "16",
   "pages": "5779",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41856964",
   "doi": "10.1097/ADM.0000000000001679",
   "title": "Prenatal Fentanyl Exposure Association With Characteristic Neonatal Anomalies",
   "authors": [
    "Mirsky E",
    "Cockerham C",
    "O'Brien J",
    "et al."
   ],
   "journal": "Journal of addiction medicine",
   "year": "2026",
   "volume": "20",
   "pages": "e12-e14",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "42115397",
   "doi": "10.1007/s00210-026-05424-4",
   "title": "Protective effect of docosahexaenoic acid (DHA) against prenatal cytarabine exposure-induced developmental toxicity in SD rat",
   "authors": [
    "Chilaka KN",
    "Nimmalapudi SN",
    "Namoju R"
   ],
   "journal": "Naunyn-Schmiedeberg's archives of pharmacology",
   "year": "2026",
   "volume": "399",
   "pages": "16451-16474",
   "pubtypes": [],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "42255658",
   "doi": "10.1016/j.toxrep.2026.102280",
   "title": "Protective role of methylcobalamin (Vit B12) and pyridoxine (Vit B6) combination against teratogenic effects induced by lead in chick embryo",
   "authors": [
    "Idrees R",
    "Kanwal MA",
    "Ahmad SN",
    "et al."
   ],
   "journal": "Toxicology reports",
   "year": "2026",
   "volume": "16",
   "pages": "102280",
   "pubtypes": [],
   "codes": [
    "1027"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41557582",
   "doi": "10.1159/000550538",
   "title": "Pseudoamniotic Band Sequence Risk Factors following Fetoscopic Laser for Twin-Twin Transfusion Syndrome",
   "authors": [
    "Lemoine FV",
    "Backley S",
    "Vilchez-Lagos G",
    "et al."
   ],
   "journal": "Fetal diagnosis and therapy",
   "year": "2026",
   "volume": "53",
   "pages": "388-398",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40983097",
   "doi": "10.1055/a-2685-5018",
   "title": "Risk of Falls and Fractures in People with Thalidomide Embryopathy",
   "authors": [
    "Beyer R",
    "Höller A",
    "Schön G"
   ],
   "journal": "Zeitschrift fur Orthopadie und Unfallchirurgie",
   "year": "2026",
   "volume": "164",
   "pages": "143-150",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "42249584",
   "doi": "10.1177/17531934261447693",
   "title": "Shared decision making in the treatment of type B ulnar polydactyly: a systematic review and meta-analysis on parental satisfaction and complications",
   "authors": [
    "Ten Berge SH",
    "Nieuwdorp NJ",
    "Burger EB",
    "et al."
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2026",
   "volume": "",
   "pages": "17531934261447693",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40549513",
   "doi": "10.1097/SCS.0000000000011570",
   "title": "Single-Cell Sequencing Reveals Thalidomide-Induced Teratogenicity in Zebrafish via Endoplasmic Reticulum Stress and Dysregulated Angiogenic Signaling",
   "authors": [
    "Zhao J",
    "Song T"
   ],
   "journal": "The Journal of craniofacial surgery",
   "year": "2026",
   "volume": "37",
   "pages": "746-752",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40964825",
   "doi": "10.1002/mgg3.70140",
   "title": "A Novel TP63 Missense Mutation in the Sumoylation Motif Causes Isolated Split-Hand/Foot Malformation 4: A Pedigree Report and Literature Review",
   "authors": [
    "Yang W",
    "Zhou J",
    "Si N",
    "et al."
   ],
   "journal": "Molecular genetics & genomic medicine",
   "year": "2025",
   "volume": "13",
   "pages": "e70140",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40913756",
   "doi": "10.1002/pd.6885",
   "title": "A Practical Prenatal Ultrasound Classification System for Lower Limb Anomalies-PRELLIM Classification",
   "authors": [
    "Arduç A",
    "van Doesburg MHM",
    "Witbreuk MMEH",
    "et al."
   ],
   "journal": "Prenatal diagnosis",
   "year": "2025",
   "volume": "45",
   "pages": "1442-1449",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41300579",
   "doi": "10.3390/children12111461",
   "title": "A Systematic Review of Digital Deformities in Pediatric Patients and Their Podiatric Treatments",
   "authors": [
    "Miralles MJC",
    "Vargas RG",
    "Vallés AJ",
    "et al."
   ],
   "journal": "Children (Basel, Switzerland)",
   "year": "2025",
   "volume": "12",
   "pages": "",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "meta",
    "review"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40615527",
   "doi": "10.1038/s41431-025-01902-0",
   "title": "A homozygous frameshift variant in the CILK1 gene causes cranioectodermal dysplasia",
   "authors": [
    "Sezer A",
    "Oner SS",
    "Saat H",
    "et al."
   ],
   "journal": "European journal of human genetics : EJHG",
   "year": "2025",
   "volume": "33",
   "pages": "1240-1251",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40599048",
   "doi": "10.1024/0301-1526/a001208",
   "title": "Cardiovascular manifestations of thalidomide embryopathy",
   "authors": [
    "Klein-Weigel PF",
    "Ding-Greiner C"
   ],
   "journal": "VASA. Zeitschrift fur Gefasskrankheiten",
   "year": "2025",
   "volume": "54",
   "pages": "299-304",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39302026",
   "doi": "10.1177/15589447241279456",
   "title": "Comparison Between Surgical Techniques for Correction of Congenital Syndactyly: A Systematic Review and Meta Analysis",
   "authors": [
    "Schirlo JM",
    "Saad Cleto A",
    "Beltrame D",
    "et al."
   ],
   "journal": "Hand (New York, N.Y.)",
   "year": "2025",
   "volume": "20",
   "pages": "523-532",
   "pubtypes": [
    "Comparative Study",
    "Meta-Analysis",
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39937006",
   "doi": "10.3390/cells14030215",
   "title": "Comprehensive Search for Genes Involved in Thalidomide Teratogenicity Using Early Differentiation Models of Human Induced Pluripotent Stem Cells: Potential Applications in Reproductive and Developmental Toxicity Testing",
   "authors": [
    "Kato Y",
    "Inaba T",
    "Shinke K",
    "et al."
   ],
   "journal": "Cells",
   "year": "2025",
   "volume": "14",
   "pages": "",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "40446690",
   "doi": "10.1016/j.psj.2025.105341",
   "title": "Development of external morphological malformations induced by hyperthermia exposure during the blastula stage in an ex-ovo (shell-less) culture of Gallus gallus domesticus embryos",
   "authors": [
    "Macias-Marin O",
    "Guerrero-Barrera AL",
    "Valdivia-Flores AG",
    "et al."
   ],
   "journal": "Poultry science",
   "year": "2025",
   "volume": "104",
   "pages": "105341",
   "pubtypes": [],
   "codes": [
    "1027"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41555917",
   "doi": "10.3389/fgene.2025.1570754",
   "title": "Familial multiple fetal cerebral arteriovenous malformations: a case report of maternal genetic susceptibility and fetal manifestation",
   "authors": [
    "Wang H",
    "Jiang Y",
    "Chen Y",
    "et al."
   ],
   "journal": "Frontiers in genetics",
   "year": "2025",
   "volume": "16",
   "pages": "1570754",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40233106",
   "doi": "10.1371/journal.pmed.1004576",
   "title": "First-trimester exposure to macrolides and risk of major congenital malformations compared with amoxicillin: A French nationwide cohort study",
   "authors": [
    "Tran A",
    "Zureik M",
    "Sibiude J",
    "et al."
   ],
   "journal": "PLoS medicine",
   "year": "2025",
   "volume": "22",
   "pages": "e1004576",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39976306",
   "doi": "10.1002/bdr2.2438",
   "title": "Maternal Diarrhea During the Periconceptional Period and the Risk of Birth Defects, National Birth Defects Prevention Study, 2006-2011",
   "authors": [
    "Waller DK",
    "Mohan Dass NL",
    "Oluwafemi OO",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2025",
   "volume": "117",
   "pages": "e2438",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40379672",
   "doi": "10.1038/s41598-025-00641-y",
   "title": "New insight into teratogenic effects of (S)-thalidomide in zebrafish embryos growing inside the chorion and subjected to electric pulses",
   "authors": [
    "Małkowska A",
    "Szymański Ł",
    "Nowakowska J",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2025",
   "volume": "15",
   "pages": "17052",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40035182",
   "doi": "10.1002/jcu.23904",
   "title": "Placental and Umbilical Cord Anomalies Detected by Ultrasound as Clinical Risk Factors of Adverse Perinatal Outcomes. Case Series Review of Selected Conditions. Part 3: Vascular Anomalies of the Umbilical Cord and Fetoplacental Vascular Malperfusion",
   "authors": [
    "Tonni G",
    "Lituania M",
    "Grisolia G",
    "et al."
   ],
   "journal": "Journal of clinical ultrasound : JCU",
   "year": "2025",
   "volume": "53",
   "pages": "863-879",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39818015",
   "doi": "10.1016/j.bjps.2024.12.008",
   "title": "Reconstructive techniques for chest and breast deformities in Poland syndrome: An up-to-date systematic review",
   "authors": [
    "Grande PK",
    "Mortell T",
    "Chang AE",
    "et al."
   ],
   "journal": "Journal of plastic, reconstructive & aesthetic surgery : JPRAS",
   "year": "2025",
   "volume": "101",
   "pages": "207-215",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39693525",
   "doi": "10.5435/JAAOS-D-24-00090",
   "title": "Risk Factors for Complications in Reconstructing Congenital Femoral Deficiency",
   "authors": [
    "Shahcheraghi GH",
    "Javid M",
    "Nemati A"
   ],
   "journal": "The Journal of the American Academy of Orthopaedic Surgeons",
   "year": "2025",
   "volume": "33",
   "pages": "e511-e521",
   "pubtypes": [],
   "codes": [
    "93323"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40904645",
   "doi": "10.5582/irdr.2025.01032",
   "title": "Secondary musculoskeletal disability and rehabilitation aspects in adults with thalidomide embryopathy: A narrative review",
   "authors": [
    "Haga N",
    "Fujitani J",
    "Kobayashi T",
    "et al."
   ],
   "journal": "Intractable & rare diseases research",
   "year": "2025",
   "volume": "14",
   "pages": "175-182",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40206497",
   "doi": "10.7759/cureus.81943",
   "title": "Stuck Together: A Systematic Review of Hand Syndactyly",
   "authors": [
    "Gowrie S",
    "Omosebi O",
    "Veith P",
    "et al."
   ],
   "journal": "Cureus",
   "year": "2025",
   "volume": "17",
   "pages": "e81943",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta",
    "review"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40198353",
   "doi": "10.1007/s00204-024-03930-z",
   "title": "Thalidomide-induced limb malformations: an update and reevaluation",
   "authors": [
    "Collins MD",
    "Scott WJ"
   ],
   "journal": "Archives of toxicology",
   "year": "2025",
   "volume": "99",
   "pages": "1643-1747",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39947980",
   "doi": "10.1016/j.clinthera.2025.01.011",
   "title": "Thalidomide: Following Tragedy, a Repurposed Molecule With Continuing Opportunities for Clinical Benefit",
   "authors": [
    "Beninger P"
   ],
   "journal": "Clinical therapeutics",
   "year": "2025",
   "volume": "47",
   "pages": "249-251",
   "pubtypes": [
    "Editorial"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "41274663",
   "doi": "10.1136/bmjpo-2025-003451",
   "title": "The aetiology distribution of birth defects based on the China Birth Cohort Study",
   "authors": [
    "Liu X",
    "Liu R",
    "Wang C",
    "et al."
   ],
   "journal": "BMJ paediatrics open",
   "year": "2025",
   "volume": "9",
   "pages": "",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40692203",
   "doi": "10.1111/scd.70074",
   "title": "Ultrasound-Guided Nerve Block With Intravenous Moderate Sedation for Dental Surgery in Thalidomide Embryopathy With Facial Hyperalgesia",
   "authors": [
    "Kawauchi A",
    "Ito T",
    "Ishii A",
    "et al."
   ],
   "journal": "Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry",
   "year": "2025",
   "volume": "45",
   "pages": "e70074",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "prosthetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39566919",
   "doi": "10.5468/ogs.24231",
   "title": "Usefulness and limitations of Chat GPT in getting information on teratogenic drugs exposed in pregnancy",
   "authors": [
    "Han JY"
   ],
   "journal": "Obstetrics & gynecology science",
   "year": "2025",
   "volume": "68",
   "pages": "1-8",
   "pubtypes": [],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "40084670",
   "doi": "10.1590/1678-4685-GMB-2024-0123",
   "title": "Van der Woude syndrome and amniotic band sequence: A clue to a common genetic etiology? A case report",
   "authors": [
    "Bossolani-Martins AL",
    "Meira JGC",
    "Kobayashi GS",
    "et al."
   ],
   "journal": "Genetics and molecular biology",
   "year": "2025",
   "volume": "48",
   "pages": "e20240123",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38343155",
   "doi": "10.1002/bdr2.2312",
   "title": "A case-control study characterizing polydactyly risk factors in Bogotá and Cali, Colombia between 2002 and 2020",
   "authors": [
    "Portilla-Rojas E",
    "Ramírez L",
    "Moreno C",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2024",
   "volume": "116",
   "pages": "e2312",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38671254",
   "doi": "10.1007/s10654-024-01125-5",
   "title": "A multidisciplinary and structured investigation of three suspected clusters of transverse upper limb reduction defects in France",
   "authors": [
    "Boudet-Berquier J",
    "Demattei C",
    "Guldner L",
    "et al."
   ],
   "journal": "European journal of epidemiology",
   "year": "2024",
   "volume": "39",
   "pages": "753-771",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37987676",
   "doi": "10.1177/17531934231213516",
   "title": "Clinical and operative risk factors for complications after Apert hand syndactyly reconstruction",
   "authors": [
    "Cordray H",
    "Graham EM",
    "Kota A",
    "et al."
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2024",
   "volume": "49",
   "pages": "617-626",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38547384",
   "doi": "10.1002/uog.27649",
   "title": "Detection of non-cardiac fetal abnormalities on ultrasound at 11-14 weeks: systematic review and meta-analysis",
   "authors": [
    "Karim JN",
    "Di Mascio D",
    "Roberts N",
    "et al."
   ],
   "journal": "Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology",
   "year": "2024",
   "volume": "64",
   "pages": "15-27",
   "pubtypes": [
    "Meta-Analysis",
    "Systematic Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39575497",
   "doi": "10.1142/S2424835524300068",
   "title": "Developing a Congenital Upper Limb Difference Registry in Australia",
   "authors": [
    "Wilks DJ",
    "McCombe DB"
   ],
   "journal": "The journal of hand surgery Asian-Pacific volume",
   "year": "2024",
   "volume": "29",
   "pages": "486-491",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Aussiehands (Australia)"
   ],
   "via": [
    "Aussiehands (Australia)"
   ]
  },
  {
   "pmid": "39080813",
   "doi": "10.1002/pd.6636",
   "title": "Fetoscopic Release of Amniotic Bands Based on the Evidence-A Systematic Review",
   "authors": [
    "Ferrer-Marquez F",
    "Peiro JL",
    "Tonni G",
    "et al."
   ],
   "journal": "Prenatal diagnosis",
   "year": "2024",
   "volume": "44",
   "pages": "1231-1241",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38411327",
   "doi": "10.1002/bdr2.2306",
   "title": "Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980-2017",
   "authors": [
    "Feldkamp ML",
    "Canfield MA",
    "Krikov S",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2024",
   "volume": "116",
   "pages": "e2306",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany), EUROCAT (EU RD Platform, JRC) (Italy)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)",
    "EUROCAT (EU RD Platform, JRC) (Italy)"
   ]
  },
  {
   "pmid": "39048352",
   "doi": "10.1265/ehpm.23-00366",
   "title": "Heavy metals and trace elements in maternal blood and prevalence of congenital limb abnormalities among newborns: the Japan Environment and Children's Study",
   "authors": [
    "Ikeda A",
    "Marsela M",
    "Miyashita C",
    "et al."
   ],
   "journal": "Environmental health and preventive medicine",
   "year": "2024",
   "volume": "29",
   "pages": "36",
   "pubtypes": [],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37285827",
   "doi": "10.1159/000531452",
   "title": "Integrative Role of the SALL4 Gene: From Thalidomide Embryopathy to Genetic Defects of the Upper Limb, Internal Organs, Cerebral Midline, and Pituitary",
   "authors": [
    "Kodytková A",
    "Dušátková P",
    "Amaratunga SA",
    "et al."
   ],
   "journal": "Hormone research in paediatrics",
   "year": "2024",
   "volume": "97",
   "pages": "106-112",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38101565",
   "doi": "10.1016/j.ejmg.2023.104903",
   "title": "LRP4 site-specific variants in the third β-propeller domain causes congenital myasthenic syndrome type 17",
   "authors": [
    "Al Jabry T",
    "Al-Hashmi N",
    "Abdelhadi B",
    "et al."
   ],
   "journal": "European journal of medical genetics",
   "year": "2024",
   "volume": "67",
   "pages": "104903",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "3258",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39168984",
   "doi": "10.1038/s41467-024-51328-3",
   "title": "Limb reduction in an Esco2 cohesinopathy mouse model is mediated by p53-dependent apoptosis and vascular disruption",
   "authors": [
    "Strasser AS",
    "Gonzalez-Reiche AS",
    "Zhou X",
    "et al."
   ],
   "journal": "Nature communications",
   "year": "2024",
   "volume": "15",
   "pages": "7154",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "3103"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38896578",
   "doi": "10.1590/1516-3180.2023.0159.R1.16022024",
   "title": "Maternal and perinatal outcomes of minimally invasive fetal surgeries: experience from two reference centers in Rio de Janeiro, Brazil",
   "authors": [
    "Ávila LM",
    "Carvalho PRN",
    "Sá RAM",
    "et al."
   ],
   "journal": "Sao Paulo medical journal = Revista paulista de medicina",
   "year": "2024",
   "volume": "142",
   "pages": "e2023159",
   "pubtypes": [
    "Multicenter Study"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39056527",
   "doi": "10.1002/bdr2.2335",
   "title": "Moderate altitude as a risk factor for isolated congenital malformations. Results from a case-control multicenter-multiregional study",
   "authors": [
    "Ibarra-Ibarra BR",
    "Luna-Muñoz L",
    "Mutchinick OM",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2024",
   "volume": "116",
   "pages": "e2335",
   "pubtypes": [
    "Multicenter Study"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38459147",
   "doi": "10.1007/s00381-024-06346-3",
   "title": "Neurosurgical intervention for the Meckel-Gruber Syndrome: A systematic review",
   "authors": [
    "Junior JHMF",
    "Junior SP",
    "Pustilnik HN",
    "et al."
   ],
   "journal": "Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery",
   "year": "2024",
   "volume": "40",
   "pages": "2161-2168",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38702055",
   "doi": "10.1177/17531934241249014",
   "title": "Parental experience after diagnosis of a congenital upper limb difference: a national survey",
   "authors": [
    "Clelland AD",
    "Lester R",
    "Duncan Ó",
    "et al."
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2024",
   "volume": "49",
   "pages": "1327-1333",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "living"
   ],
   "notes": [
    "published on the website of Reach (United Kingdom)"
   ],
   "via": [
    "Reach (United Kingdom)"
   ]
  },
  {
   "pmid": "38340146",
   "doi": "10.1007/s12519-023-00786-8",
   "title": "Perinatal prevalence of birth defects in the Mainland of China, 2000-2021: a systematic review and meta-analysis",
   "authors": [
    "Kang LY",
    "Guo ZR",
    "Shang WJ",
    "et al."
   ],
   "journal": "World journal of pediatrics : WJP",
   "year": "2024",
   "volume": "20",
   "pages": "669-681",
   "pubtypes": [
    "Meta-Analysis",
    "Systematic Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38014617",
   "doi": "10.1002/bdr2.2274",
   "title": "Prevalence of congenital anomalies according to maternal race and ethnicity, Texas, 1999-2018",
   "authors": [
    "Schraw JM",
    "Jaime E",
    "Shumate CJ",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2024",
   "volume": "116",
   "pages": "e2274",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39589106",
   "doi": "10.1002/bdr2.2416",
   "title": "Protective Role of Vitamin B6 Against Teratogenic Effects Induced by Lead in Chick Embryo",
   "authors": [
    "Ahmad W",
    "Kanwal MA",
    "Inayat I",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2024",
   "volume": "116",
   "pages": "e2416",
   "pubtypes": [],
   "codes": [
    "1027",
    "2879"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39466184",
   "doi": "10.1097/SCS.0000000000010659",
   "title": "Rare Combination of Congenital Microtia and Limb Malformations: Analysis of Etiology and Treatment",
   "authors": [
    "Gao D",
    "Luo P",
    "Guo R",
    "et al."
   ],
   "journal": "The Journal of craniofacial surgery",
   "year": "2024",
   "volume": "",
   "pages": "",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39220272",
   "doi": "10.5582/irdr.2024.01035",
   "title": "Skeletal computed tomography findings of upper extremities in middle-aged persons with thalidomide embryopathy",
   "authors": [
    "Kamimura C",
    "Fujitani J",
    "Aizawa I",
    "et al."
   ],
   "journal": "Intractable & rare diseases research",
   "year": "2024",
   "volume": "13",
   "pages": "185-189",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38336121",
   "doi": "10.1016/j.ejmg.2024.104920",
   "title": "TBX5 variants and cardiac phenotype: A systematic review of the literature and a novel variant",
   "authors": [
    "Møller Nielsen AK",
    "Dehn AM",
    "Hjortdal V",
    "et al."
   ],
   "journal": "European journal of medical genetics",
   "year": "2024",
   "volume": "68",
   "pages": "104920",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "392"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38318695",
   "doi": "10.1080/09638288.2024.2307357",
   "title": "The impact of ageing on the health and wellbeing of people with thalidomide embryopathy: a comparison of the health impact with the general population",
   "authors": [
    "Sagoe K",
    "Owens WA",
    "Loyd R",
    "et al."
   ],
   "journal": "Disability and rehabilitation",
   "year": "2024",
   "volume": "46",
   "pages": "5029-5037",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37838596",
   "doi": "10.1016/j.jos.2023.10.001",
   "title": "What are the key risk factors of keloid formation after repair of syndactyly of the toe?",
   "authors": [
    "Ishigaki T",
    "Akita S",
    "Udagawa A",
    "et al."
   ],
   "journal": "Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association",
   "year": "2024",
   "volume": "29",
   "pages": "1406-1410",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36728793",
   "doi": "10.1097/PRS.0000000000010116",
   "title": "A Systematic Review of Vascularized and Nonvascularized Toe Transfer for Reconstruction of Congenital Hand Differences",
   "authors": [
    "Meyers A",
    "Bassiri Gharb B",
    "Rampazzo A"
   ],
   "journal": "Plastic and reconstructive surgery",
   "year": "2023",
   "volume": "151",
   "pages": "1256-1273",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "1570"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36804539",
   "doi": "10.1038/s41419-023-05681-8",
   "title": "A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis",
   "authors": [
    "Zhang L",
    "Fang Z",
    "Cheng G",
    "et al."
   ],
   "journal": "Cell death & disease",
   "year": "2023",
   "volume": "14",
   "pages": "145",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39669238",
   "doi": "10.1016/j.gimo.2023.100834",
   "title": "A novel syndrome associated with prenatal fentanyl exposure",
   "authors": [
    "Wadman E",
    "Fernandes E",
    "Muss C",
    "et al."
   ],
   "journal": "Genetics in medicine open",
   "year": "2023",
   "volume": "1",
   "pages": "100834",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37021538",
   "doi": "10.1177/17531934231164093",
   "title": "Age-related changes in patients with upper limb thalidomide embryopathy in the United Kingdom",
   "authors": [
    "Markiewicz M",
    "Stirling P",
    "Brennan S",
    "et al."
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2023",
   "volume": "48",
   "pages": "773-780",
   "pubtypes": [],
   "codes": [
    "93321",
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "36584346",
   "doi": "10.1002/ajmg.a.63107",
   "title": "Amniotic band syndrome and limb body wall complex in Europe 1980-2019",
   "authors": [
    "Bergman JEH",
    "Barišić I",
    "Addor MC",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2023",
   "volume": "191",
   "pages": "995-1006",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Amniotic band syndrome (prevalence at birth, Europe)",
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany), EUROCAT (EU RD Platform, JRC) (Italy), PRCM: Polish registry of congenital malformations - contributes to the EUROCAT network (Poland), REMACOR: La Réunion Fench Island registry of congenital anomalies - contributes to the EUROCAT network (France)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)",
    "EUROCAT (EU RD Platform, JRC) (Italy)",
    "Orphanet",
    "PRCM: Polish registry of congenital malformations - contributes to the EUROCAT network (Poland)",
    "REMACOR: La Réunion Fench Island registry of congenital anomalies - contributes to the EUROCAT network (France)"
   ]
  },
  {
   "pmid": "36986467",
   "doi": "10.3390/ph16030368",
   "title": "Augmentation of Pectoral Fin Teratogenicity by Thalidomide in Human Cytochrome P450 3A-Expressing Zebrafish",
   "authors": [
    "Dong W",
    "Akasaka I",
    "Komiyama A",
    "et al."
   ],
   "journal": "Pharmaceuticals (Basel, Switzerland)",
   "year": "2023",
   "volume": "16",
   "pages": "",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38071979",
   "doi": "10.1016/S0140-6736(23)02748-4",
   "title": "Australia delivers apology to survivors of thalidomide",
   "authors": [
    "Kirby T"
   ],
   "journal": "Lancet (London, England)",
   "year": "2023",
   "volume": "402",
   "pages": "2182",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37333142",
   "doi": "10.1101/2023.06.07.544132",
   "title": "Autonomous and non-cell autonomous etiology of ciliopathy associated structural birth defects",
   "authors": [
    "Francis R",
    "San Agustin JT",
    "Szabo Rogers HL",
    "et al."
   ],
   "journal": "bioRxiv : the preprint server for biology",
   "year": "2023",
   "volume": "",
   "pages": "",
   "pubtypes": [
    "Preprint"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37791865",
   "doi": "10.1177/1098612X231193557",
   "title": "Cardiomyopathy associated 5 (CMYA5) implicated as a genetic risk factor for radial hemimelia in Siamese cats",
   "authors": [
    "Bilgen N",
    "Çınar Kul B",
    "Akkurt MY",
    "et al."
   ],
   "journal": "Journal of feline medicine and surgery",
   "year": "2023",
   "volume": "25",
   "pages": "1098612X231193557",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93321"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37211796",
   "doi": "10.1177/17531934231175304",
   "title": "Commentary on Markiewicz et al. Age-related changes in patients with upper limb thalidomide embryopathy in the United Kingdom",
   "authors": [
    "Farr S"
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2023",
   "volume": "48",
   "pages": "781-782",
   "pubtypes": [
    "Comment"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37974291",
   "doi": "10.1186/s13643-023-02362-7",
   "title": "Correction of symbrachydactyly: a systematic review of surgical options",
   "authors": [
    "Bartsch A",
    "Nikkhah D",
    "Miller R",
    "et al."
   ],
   "journal": "Systematic reviews",
   "year": "2023",
   "volume": "12",
   "pages": "218",
   "pubtypes": [],
   "codes": [
    "1570",
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36606449",
   "doi": "10.1002/dvdy.565",
   "title": "Dysregulation of Grainyhead-like 3 expression causes widespread developmental defects",
   "authors": [
    "Deng Z",
    "Butt T",
    "Arhatari BD",
    "et al."
   ],
   "journal": "Developmental dynamics : an official publication of the American Association of Anatomists",
   "year": "2023",
   "volume": "252",
   "pages": "647-667",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37665243",
   "doi": "10.1002/jcu.23549",
   "title": "Ectrodactyly-ectodermal dysplasia-clefting syndrome. Prenatal prospective ultrasound diagnosis",
   "authors": [
    "Orlandi G",
    "Di Girolamo R",
    "Carbone L",
    "et al."
   ],
   "journal": "Journal of clinical ultrasound : JCU",
   "year": "2023",
   "volume": "51",
   "pages": "1348-1355",
   "pubtypes": [
    "Case Reports",
    "Systematic Review"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36300660",
   "doi": "10.1111/jdv.18690",
   "title": "Epidemiology of aplasia cutis congenita: A population-based study in Europe",
   "authors": [
    "Coi A",
    "Barisic I",
    "Garne E",
    "et al."
   ],
   "journal": "Journal of the European Academy of Dermatology and Venereology : JEADV",
   "year": "2023",
   "volume": "37",
   "pages": "581-589",
   "pubtypes": [],
   "codes": [
    "974"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany), EUROCAT (EU RD Platform, JRC) (Italy), PRCM: Polish registry of congenital malformations - contributes to the EUROCAT network (Poland), REMACOR: La Réunion Fench Island registry of congenital anomalies - contributes to the EUROCAT network (France)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)",
    "EUROCAT (EU RD Platform, JRC) (Italy)",
    "PRCM: Polish registry of congenital malformations - contributes to the EUROCAT network (Poland)",
    "REMACOR: La Réunion Fench Island registry of congenital anomalies - contributes to the EUROCAT network (France)"
   ]
  },
  {
   "pmid": "37547102",
   "doi": "10.3389/fped.2023.1165477",
   "title": "Epidemiology of birth defects based on a birth defects surveillance system in southwestern China and the associated risk factors",
   "authors": [
    "Peng Z",
    "Wei J",
    "Chen B",
    "et al."
   ],
   "journal": "Frontiers in pediatrics",
   "year": "2023",
   "volume": "11",
   "pages": "1165477",
   "pubtypes": [],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37710961",
   "doi": "10.1016/j.xhgg.2023.100238",
   "title": "Gain-of-function MYCN causes a megalencephaly-polydactyly syndrome manifesting mirror phenotypes of Feingold syndrome",
   "authors": [
    "Nishio Y",
    "Kato K",
    "Tran Mau-Them F",
    "et al."
   ],
   "journal": "HGG advances",
   "year": "2023",
   "volume": "4",
   "pages": "100238",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37445217",
   "doi": "10.3390/jcm12134181",
   "title": "Maternal Cigarette Smoking and Congenital Upper and Lower Limb Differences: A Systematic Review and Meta-Analysis",
   "authors": [
    "Cevik J",
    "Salehi O",
    "Gaston J",
    "et al."
   ],
   "journal": "Journal of clinical medicine",
   "year": "2023",
   "volume": "12",
   "pages": "",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "meta",
    "review"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36708132",
   "doi": "10.1002/ajmg.a.63122",
   "title": "Novel noncanonical splice site variant causes mild CHD7-related disorder with variable intrafamilial expressivity",
   "authors": [
    "Boschann F",
    "Kosmehl S",
    "Bloching M",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2023",
   "volume": "191",
   "pages": "1128-1132",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38222129",
   "doi": "10.7759/cureus.50465",
   "title": "Review of Teratogenic Effects of Leflunomide, Accutane, Thalidomide, Warfarin, Tetracycline, and Angiotensin-Converting Enzyme Inhibitors",
   "authors": [
    "Abadie RB",
    "Keller CL",
    "Jones NT",
    "et al."
   ],
   "journal": "Cureus",
   "year": "2023",
   "volume": "15",
   "pages": "e50465",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "38034494",
   "doi": "10.3389/fgene.2023.1247557",
   "title": "Review of the phenotypes and genotypes of Bardet-Biedl syndrome from China",
   "authors": [
    "Xin-Yi Z",
    "Yang-Li D",
    "Ling-Hui Z"
   ],
   "journal": "Frontiers in genetics",
   "year": "2023",
   "volume": "14",
   "pages": "1247557",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37122977",
   "doi": "10.7759/cureus.38140",
   "title": "Risk Factors for 30-Day Unplanned Re-Operation in Pediatric Upper Extremity Surgery: A National Surgical Quality Improvement Program (NSQIP)-Pediatric Analysis",
   "authors": [
    "Chiu AK",
    "Quan T",
    "Kraft D",
    "et al."
   ],
   "journal": "Cureus",
   "year": "2023",
   "volume": "15",
   "pages": "e38140",
   "pubtypes": [],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35414337",
   "doi": "10.1080/15513815.2022.2064018",
   "title": "Severe Adams-Oliver Syndrome after Maternal COVID-19 Infection Could Be Another Effect of the SARS-CoV-2 Inflammatory Storm? Case Report",
   "authors": [
    "Okido MM",
    "Ragazini CS",
    "Duarte G",
    "et al."
   ],
   "journal": "Fetal and pediatric pathology",
   "year": "2023",
   "volume": "42",
   "pages": "131-136",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "974"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37226469",
   "doi": "10.1177/17531934231177425",
   "title": "Thalidomide upper limb embryopathy - pathogenesis, past and present management and future considerations",
   "authors": [
    "Vargesson N",
    "Hooper G",
    "Giddins G",
    "et al."
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2023",
   "volume": "48",
   "pages": "699-709",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "37165329",
   "doi": "10.1186/s12884-023-05660-z",
   "title": "The changing epidemiology of syndactyly in Chinese newborns: a nationwide surveillance-based study",
   "authors": [
    "Chen ZY",
    "Li WY",
    "Xu WL",
    "et al."
   ],
   "journal": "BMC pregnancy and childbirth",
   "year": "2023",
   "volume": "23",
   "pages": "334",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "China, syndactyly"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "36798679",
   "doi": "10.1177/2050313X231154635",
   "title": "Total knee arthroplasty and patelloplasty in a patient with phocomelia caused by thalidomide",
   "authors": [
    "Fahlbusch H",
    "Ohlmeier M",
    "Mau H",
    "et al."
   ],
   "journal": "SAGE open medical case reports",
   "year": "2023",
   "volume": "11",
   "pages": "2050313X231154635",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "prosthetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36603815",
   "doi": "10.1055/a-2002-7954",
   "title": "[Correction: Replantation of the Functionally Dominant Little Finger in Dysmelia with Thumb Aplasia (Blauth type IV) after Fetal Damage from Thalidomide (Contergan) (Blauth Typ IV) and Wrist Deformity]",
   "authors": [
    "Steinhauer F",
    "Terzis A",
    "Gruenewald J",
    "et al."
   ],
   "journal": "Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...",
   "year": "2023",
   "volume": "",
   "pages": "",
   "pubtypes": [
    "Published Erratum"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36513326",
   "doi": "10.1055/a-1933-2949",
   "title": "[Replantation of the Functionally Dominant Little Finger in Dysmelia with Thumb Aplasia (Blauth type IV) after Fetal Damage from Thalidomide (Contergan) (Blauth Typ IV) and Wrist Deformity]",
   "authors": [
    "Steinhauer F",
    "Terzis A",
    "Gruenewald J",
    "et al."
   ],
   "journal": "Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...",
   "year": "2023",
   "volume": "55",
   "pages": "155-158",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35208525",
   "doi": "10.3390/medicina58020202",
   "title": "A Novel Mutation in a Gene Causes Sclerosteosis in a Family of Mediterranean Origin",
   "authors": [
    "Ekhzaimy AA",
    "Alyusuf EY",
    "Alswailem M",
    "et al."
   ],
   "journal": "Medicina (Kaunas, Lithuania)",
   "year": "2022",
   "volume": "58",
   "pages": "",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35449659",
   "doi": "10.7759/cureus.23297",
   "title": "Adams-Oliver Syndrome: A Rare Congenital Disorder",
   "authors": [
    "Rashid S",
    "Azeem S",
    "Riaz S"
   ],
   "journal": "Cureus",
   "year": "2022",
   "volume": "14",
   "pages": "e23297",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "974"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Adams-Oliver syndrome (point prevalence, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "36353751",
   "doi": "10.1002/bdr2.2123",
   "title": "Amelia and phocomelia in Finland: Characteristics and prevalences in a nationwide population-based study",
   "authors": [
    "Pakkasjärvi N",
    "Syvänen J",
    "Wiro M",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2022",
   "volume": "114",
   "pages": "1427-1433",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "Finland, amelia and phocomelia"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "35181024",
   "doi": "10.1016/j.tjog.2021.11.022",
   "title": "Application of quantitative fluorescent polymerase chain reaction analysis for the rapid confirmation of trisomy 13 of maternal origin in a pregnancy with fetal holoprosencephaly, cyclopia, polydactyly, omphalocele and cell culture failure",
   "authors": [
    "Chen CP",
    "Wang LK",
    "Chern SR",
    "et al."
   ],
   "journal": "Taiwanese journal of obstetrics & gynecology",
   "year": "2022",
   "volume": "61",
   "pages": "135-137",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35362676",
   "doi": "10.24272/j.issn.2095-8137.2021.291",
   "title": "BMPR-IB gene disruption causes severe limb deformities in pigs",
   "authors": [
    "Yang Q",
    "Qiao CM",
    "Liu WW",
    "et al."
   ],
   "journal": "Zoological research",
   "year": "2022",
   "volume": "43",
   "pages": "391-403",
   "pubtypes": [],
   "codes": [
    "93323"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35502959",
   "doi": "10.1097/SAP.0000000000003219",
   "title": "Bilateral Transverse Upper Gracilis Flaps for Unilateral Breast Reconstruction: A 4-Year Retrospective Study of the \"2-in-1\" Technique and a Systematic Review With Meta-analysis",
   "authors": [
    "Christopoulos G",
    "Khoury A",
    "Sergentanis TN",
    "et al."
   ],
   "journal": "Annals of plastic surgery",
   "year": "2022",
   "volume": "89",
   "pages": "400-407",
   "pubtypes": [
    "Meta-Analysis",
    "Systematic Review"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35571055",
   "doi": "10.3389/fgene.2022.878274",
   "title": "Case Report: Biallelic Variant in the tRNA Methyltransferase Domain of the AlkB Homolog 8 Causes Syndromic Intellectual Disability",
   "authors": [
    "Waqas A",
    "Nayab A",
    "Shaheen S",
    "et al."
   ],
   "journal": "Frontiers in genetics",
   "year": "2022",
   "volume": "13",
   "pages": "878274",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "39195866",
   "doi": "10.1038/s44161-022-00080-2",
   "title": "Case report study of thalidomide therapy in 18 patients with severe arteriovenous malformation﻿s",
   "authors": [
    "Boon LM",
    "Dekeuleneer V",
    "Coulie J",
    "et al."
   ],
   "journal": "Nature cardiovascular research",
   "year": "2022",
   "volume": "1",
   "pages": "562-567",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "published on the website of ERN [VASCERN] - VASCERN Registries (France)"
   ],
   "via": [
    "ERN [VASCERN] - VASCERN Registries (France)"
   ]
  },
  {
   "pmid": "35521048",
   "doi": "10.1002/ccr3.5795",
   "title": "Case report: Bilateral simple Syndactyly in a toddler with maternal exposure to cabergoline",
   "authors": [
    "Afshar S",
    "Abbasinazari M",
    "Darvishi B",
    "et al."
   ],
   "journal": "Clinical case reports",
   "year": "2022",
   "volume": "10",
   "pages": "e05795",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35034947",
   "doi": "10.12659/MSM.933782",
   "title": "Epidemiology of Birth Defects in Eastern China and the Associated Risk Factors",
   "authors": [
    "Wang QQ",
    "He CY",
    "Mei J",
    "et al."
   ],
   "journal": "Medical science monitor : international medical journal of experimental and clinical research",
   "year": "2022",
   "volume": "28",
   "pages": "e933782",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34989322",
   "doi": "10.1080/15384101.2021.2023304",
   "title": "Esco2 and cohesin regulate CRL4 ubiquitin ligase ddb1 expression and thalidomide teratogenicity",
   "authors": [
    "Sanchez AC",
    "Thren ED",
    "Iovine MK",
    "et al."
   ],
   "journal": "Cell cycle (Georgetown, Tex.)",
   "year": "2022",
   "volume": "21",
   "pages": "501-513",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "3103",
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34670449",
   "doi": "10.1080/13816810.2021.1989601",
   "title": "Eye and ocular adnexa manifestations of MED12-related disorders",
   "authors": [
    "Shah A",
    "Bapna M",
    "Al-Saif H",
    "et al."
   ],
   "journal": "Ophthalmic genetics",
   "year": "2022",
   "volume": "43",
   "pages": "126-129",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36694679",
   "doi": "10.52547/wjps.11.3.13",
   "title": "Functional and Aesthetic Outcomes of the Anterolateral Thigh Flap in Reconstruction of Upper Limb Defects: A Systematic Review",
   "authors": [
    "Hagiga A",
    "Aly M",
    "Kadhum M",
    "et al."
   ],
   "journal": "World journal of plastic surgery",
   "year": "2022",
   "volume": "11",
   "pages": "13-22",
   "pubtypes": [
    "Review"
   ],
   "codes": [],
   "topics": [
    "meta",
    "review"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36177858",
   "doi": "10.1002/bdr2.2092",
   "title": "Genetic evaluation of HAND2 gene and its effects on thalidomide embryopathy",
   "authors": [
    "Rengel BD",
    "Kowalski TW",
    "Bremm JM",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2022",
   "volume": "114",
   "pages": "1354-1363",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36523353",
   "doi": "10.3389/fcvm.2022.1021009",
   "title": "Geno- and phenotypic characteristics and clinical outcomes of CACNA1C gene mutation associated Timothy syndrome, \"cardiac only\" Timothy syndrome and isolated long QT syndrome 8: A systematic review",
   "authors": [
    "Borbás J",
    "Vámos M",
    "Hategan L",
    "et al."
   ],
   "journal": "Frontiers in cardiovascular medicine",
   "year": "2022",
   "volume": "9",
   "pages": "1021009",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35666030",
   "doi": "10.1002/bdr2.2051",
   "title": "Health-related quality of life after 50 years in individuals with thalidomide embryopathy: Evidence from a German cross-sectional survey",
   "authors": [
    "Niecke A",
    "Peters KM",
    "Alayli A",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2022",
   "volume": "114",
   "pages": "714-724",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34452798",
   "doi": "10.1016/j.jhsa.2021.07.004",
   "title": "Histopathological, Ultrastructural, and Immunohistochemical Findings in Radial Longitudinal Deficiency: A Prospective, Observational Study",
   "authors": [
    "Mittal S",
    "Garg B",
    "Mehta N",
    "et al."
   ],
   "journal": "The Journal of hand surgery",
   "year": "2022",
   "volume": "47",
   "pages": "789.e1-789.e8",
   "pubtypes": [
    "Observational Study"
   ],
   "codes": [
    "93321"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Isolated radial hemimelia (point prevalence, Worldwide)",
    "cited by Orphanet for Isolated radial hemimelia (prevalence at birth, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "36347939",
   "doi": "10.1038/s41598-022-23512-2",
   "title": "Increased Ca(V)1.2 late current by a CACNA1C p.R412M variant causes an atypical Timothy syndrome without syndactyly",
   "authors": [
    "Ozawa J",
    "Ohno S",
    "Melgari D",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2022",
   "volume": "12",
   "pages": "18984",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35813538",
   "doi": "10.1007/s43465-022-00651-2",
   "title": "Management of Anterior Cruciate Ligament Aplasia for the Arthroscopy Surgeons: A Systematic Review",
   "authors": [
    "Kambhampati SBS",
    "Vishwanathan K",
    "Vasudeva N",
    "et al."
   ],
   "journal": "Indian journal of orthopaedics",
   "year": "2022",
   "volume": "56",
   "pages": "1123-1138",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "93323"
   ],
   "topics": [
    "meta",
    "review"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36684928",
   "doi": "10.3389/fpubh.2022.1017644",
   "title": "Maternal exposure to ambient air pollution and risk of congenital heart defects in Suzhou, China",
   "authors": [
    "Sun L",
    "Wu Q",
    "Wang H",
    "et al."
   ],
   "journal": "Frontiers in public health",
   "year": "2022",
   "volume": "10",
   "pages": "1017644",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35504638",
   "doi": "10.1136/bmjopen-2020-048092",
   "title": "Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes: cohort study of 151 141 singleton pregnancies",
   "authors": [
    "Zafeiri A",
    "Raja EA",
    "Mitchell RT",
    "et al."
   ],
   "journal": "BMJ open",
   "year": "2022",
   "volume": "12",
   "pages": "e048092",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34343375",
   "doi": "10.1111/jpc.15673",
   "title": "Pre-natal and post-natal diagnosis of congenital upper limb differences: The first 3 years of the Australian Hand Difference Register",
   "authors": [
    "O'Keefe D",
    "Kennedy J",
    "McCombe D",
    "et al."
   ],
   "journal": "Journal of paediatrics and child health",
   "year": "2022",
   "volume": "58",
   "pages": "122-128",
   "pubtypes": [],
   "codes": [
    "1570",
    "2440",
    "2911",
    "2913",
    "392",
    "93321"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "published on the website of Aussiehands (Australia)"
   ],
   "via": [
    "Aussiehands (Australia)"
   ]
  },
  {
   "pmid": "36369770",
   "doi": "10.1002/bdr2.2122",
   "title": "Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries",
   "authors": [
    "Morris JK",
    "Wellesley D",
    "Limb E",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2022",
   "volume": "114",
   "pages": "1417-1426",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany), PRCM: Polish registry of congenital malformations - contributes to the EUROCAT network (Poland)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)",
    "PRCM: Polish registry of congenital malformations - contributes to the EUROCAT network (Poland)",
    "PubMed search"
   ]
  },
  {
   "pmid": "36120500",
   "doi": "10.1016/j.jpra.2022.05.002",
   "title": "Primary treatment of type B post-axial ulnar polydactyly: A systematic review and meta-analysis",
   "authors": [
    "Samarendra H",
    "Wade RG",
    "Glanvill L",
    "et al."
   ],
   "journal": "JPRAS open",
   "year": "2022",
   "volume": "34",
   "pages": "21-33",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta",
    "review"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36427972",
   "doi": "10.1016/j.tjog.2022.08.008",
   "title": "Rapid confirmation of trisomy 13 of maternal origin by QF-PCR following postmortem tissue cell culture failure in a pregnancy with trisomy 13 at amniocentesis and fetal postaxial polydactyly and facial cleft",
   "authors": [
    "Chen CP",
    "Chen SW",
    "Huang JP",
    "et al."
   ],
   "journal": "Taiwanese journal of obstetrics & gynecology",
   "year": "2022",
   "volume": "61",
   "pages": "1048-1052",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36116424",
   "doi": "10.1016/j.clinph.2022.08.020",
   "title": "Split-hand index for amyotrophic lateral sclerosis diagnosis: A frequentist and Bayesian meta-analysis",
   "authors": [
    "Lu WZ",
    "Lin HA",
    "Hou SK",
    "et al."
   ],
   "journal": "Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology",
   "year": "2022",
   "volume": "143",
   "pages": "56-66",
   "pubtypes": [
    "Meta-Analysis",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33642221",
   "doi": "10.1016/j.fas.2021.02.006",
   "title": "Surgical treatment in child's congenital toe syndactyly: Risk factor of recurrence, complication and poor clinical outcomes",
   "authors": [
    "Langlais T",
    "Rougereau G",
    "Marty-Diloy T",
    "et al."
   ],
   "journal": "Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons",
   "year": "2022",
   "volume": "28",
   "pages": "107-113",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35907958",
   "doi": "10.1007/s00438-022-01930-1",
   "title": "The molecular genetics of human appendicular skeleton",
   "authors": [
    "Ahmad S",
    "Ali MZ",
    "Muzammal M",
    "et al."
   ],
   "journal": "Molecular genetics and genomics : MGG",
   "year": "2022",
   "volume": "297",
   "pages": "1195-1214",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "2440",
    "2913",
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "35582950",
   "doi": "10.1111/jcmm.17326",
   "title": "Whole-exome sequencing identified novel variants in CPLANE1 that causes oral-facial-digital syndrome Ⅵ by inducing primary cilia abnormality",
   "authors": [
    "Qian W",
    "Liu X",
    "Wang Z",
    "et al."
   ],
   "journal": "Journal of cellular and molecular medicine",
   "year": "2022",
   "volume": "26",
   "pages": "3213-3222",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36325780",
   "doi": "10.3881/j.issn.1000-503X.14589",
   "title": "[Multiple Correspondence of Abnormal Birth History with Genetic and Environmental Risk Factors]",
   "authors": [
    "Yu M",
    "Ping ZG",
    "Song H",
    "et al."
   ],
   "journal": "Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae",
   "year": "2022",
   "volume": "44",
   "pages": "822-827",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36126927",
   "doi": "10.1055/a-1893-0221",
   "title": "[National Competence Network Contergan - Ensuring medical care for people with thalidomide embryopathy]",
   "authors": [
    "Beyer R",
    "Peters KM",
    "Schulte-Hillen J",
    "et al."
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "2022",
   "volume": "147",
   "pages": "1281-1285",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "36470274",
   "doi": "10.1055/a-1951-0792",
   "title": "[Thalidomide embryopathy 60 years]",
   "authors": [
    "Passarge E"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "2022",
   "volume": "147",
   "pages": "1635-1638",
   "pubtypes": [
    "English Abstract",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33169370",
   "doi": "10.1111/cge.13878",
   "title": "A BBS1 SVA F retrotransposon insertion is a frequent cause of Bardet-Biedl syndrome",
   "authors": [
    "Delvallée C",
    "Nicaise S",
    "Antin M",
    "et al."
   ],
   "journal": "Clinical genetics",
   "year": "2021",
   "volume": "99",
   "pages": "318-324",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "33776623",
   "doi": "10.1159/000512062",
   "title": "A Frameshift Variant in KIAA0825 Causes Postaxial Polydactyly",
   "authors": [
    "Bilal M",
    "Ahmad W"
   ],
   "journal": "Molecular syndromology",
   "year": "2021",
   "volume": "12",
   "pages": "20-24",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34721536",
   "doi": "10.3389/fgene.2021.746949",
   "title": "A Novel Homozygous Missense Mutation in the Zinc Finger DNA Binding Domain of GLI1 Causes Recessive Post-Axial Polydactyly",
   "authors": [
    "Umair M",
    "Ahmad F",
    "Ahmad S",
    "et al."
   ],
   "journal": "Frontiers in genetics",
   "year": "2021",
   "volume": "12",
   "pages": "746949",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33847750",
   "doi": "10.1001/jamanetworkopen.2021.5708",
   "title": "Association of Gestational Opioid Exposure and Risk of Major and Minor Congenital Malformations",
   "authors": [
    "Wen X",
    "Belviso N",
    "Murray E",
    "et al."
   ],
   "journal": "JAMA network open",
   "year": "2021",
   "volume": "4",
   "pages": "e215708",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33442900",
   "doi": "10.1002/ajmg.a.62068",
   "title": "Clinical and molecular characterizations of 11 new patients with type 1 Feingold syndrome: Proposal for selecting diagnostic criteria and further genetic testing in patients with severe phenotype",
   "authors": [
    "Tedesco MG",
    "Lonardo F",
    "Ceccarini C",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2021",
   "volume": "185",
   "pages": "1204-1210",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "34249098",
   "doi": "10.3389/fgene.2021.680217",
   "title": "Comparative Genomics Identifies Putative Interspecies Mechanisms Underlying Crbn-Sall4-Linked Thalidomide Embryopathy",
   "authors": [
    "Kowalski TW",
    "Caldas-Garcia GB",
    "Gomes JDA",
    "et al."
   ],
   "journal": "Frontiers in genetics",
   "year": "2021",
   "volume": "12",
   "pages": "680217",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34067522",
   "doi": "10.3390/genes12050748",
   "title": "Ectodermal Dysplasia-Syndactyly Syndrome with Toe-Only Minimal Syndactyly Due to a Novel Mutation in NECTIN4: A Case Report and Literature Review",
   "authors": [
    "Rotunno R",
    "Diociaiuti A",
    "Dentici ML",
    "et al."
   ],
   "journal": "Genes",
   "year": "2021",
   "volume": "12",
   "pages": "",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "33690710",
   "doi": "10.1371/journal.pone.0248105",
   "title": "Epidemiology of congenital upper limb anomalies in Korea: A nationwide population-based study",
   "authors": [
    "Shin YH",
    "Baek GH",
    "Kim YJ",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2021",
   "volume": "16",
   "pages": "e0248105",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "Korea, congenital upper limb anomalies"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "33222112",
   "doi": "10.1007/s00590-020-02831-y",
   "title": "How should we lengthen post-traumatic limb defects? a systematic review and comparison of motorized lengthening systems, combined internal and external fixation and external fixation alone",
   "authors": [
    "Axelrod D",
    "Rubinger L",
    "Shah A",
    "et al."
   ],
   "journal": "European journal of orthopaedic surgery & traumatology : orthopedie traumatologie",
   "year": "2021",
   "volume": "31",
   "pages": "1015-1022",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34331266",
   "doi": "10.1007/s43441-021-00327-3",
   "title": "Implementation of a Pregnancy Prevention Programme (PPP) with a Controlled Distribution System (CDS) for the Generic Teratogenic Phthalimides Thalidomide, Lenalidomide and Pomalidomide",
   "authors": [
    "Mueller M",
    "Lewis DJ"
   ],
   "journal": "Therapeutic innovation & regulatory science",
   "year": "2021",
   "volume": "55",
   "pages": "1155-1164",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33779067",
   "doi": "10.1002/bdr2.1887",
   "title": "Limited surface examination to evaluate potential teratogens in a resource-limited setting",
   "authors": [
    "Holmes LB",
    "Nasri HZ",
    "Hunt AT",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2021",
   "volume": "113",
   "pages": "702-707",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33872360",
   "doi": "10.7547/20-021",
   "title": "Longitudinal Epiphyseal Bracket as an Overlooked Etiology of Congenital-Residual Hallux Varus: A Case Report",
   "authors": [
    "Kadıoğlu B",
    "Güven M",
    "Akman B",
    "et al."
   ],
   "journal": "Journal of the American Podiatric Medical Association",
   "year": "2021",
   "volume": "111",
   "pages": "",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33673226",
   "doi": "10.3390/children8020138",
   "title": "Maternal Risk Factors Associated with Limb Reduction Defects: Data from the Polish Registry of Congenital Malformations (PRCM)",
   "authors": [
    "Materna-Kiryluk A",
    "Wisniewska K",
    "Wieckowska B",
    "et al."
   ],
   "journal": "Children (Basel, Switzerland)",
   "year": "2021",
   "volume": "8",
   "pages": "",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "published on the website of PRCM: Polish registry of congenital malformations - contributes to the EUROCAT network (Poland)"
   ],
   "via": [
    "PRCM: Polish registry of congenital malformations - contributes to the EUROCAT network (Poland)",
    "PubMed search"
   ]
  },
  {
   "pmid": "33118065",
   "doi": "10.1007/s11356-020-11351-5",
   "title": "Maternal exposure to ambient SO(2) and risk of polydactyly and syndactyly: a population-based case-control study in Liaoning Province, China",
   "authors": [
    "Jiang YT",
    "Gong TT",
    "Zhang JY",
    "et al."
   ],
   "journal": "Environmental science and pollution research international",
   "year": "2021",
   "volume": "28",
   "pages": "11289-11301",
   "pubtypes": [],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34060120",
   "doi": "10.1111/ppe.12775",
   "title": "Maternal periconceptional folic acid supplements use and fetus risk for limb defects",
   "authors": [
    "Zhang J",
    "Jin L",
    "Wang D",
    "et al."
   ],
   "journal": "Paediatric and perinatal epidemiology",
   "year": "2021",
   "volume": "35",
   "pages": "645-653",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33438777",
   "doi": "10.1111/ppe.12740",
   "title": "Maternal risk factors for congenital limb deficiencies: A population-based case-control study",
   "authors": [
    "Syvänen J",
    "Nietosvaara Y",
    "Hurme S",
    "et al."
   ],
   "journal": "Paediatric and perinatal epidemiology",
   "year": "2021",
   "volume": "35",
   "pages": "450-458",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34936293",
   "doi": "10.1615/CritRevEukaryotGeneExpr.2021038555",
   "title": "Molecular Etiology in Thumb Polydactyly in Mutated GLI3 Mouse Gene",
   "authors": [
    "Wang T",
    "Dou YC",
    "Xuan ZP",
    "et al."
   ],
   "journal": "Critical reviews in eukaryotic gene expression",
   "year": "2021",
   "volume": "31",
   "pages": "69-83",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33083874",
   "doi": "10.1007/s00381-020-04934-7",
   "title": "Nervous system involvement in Pfeiffer syndrome",
   "authors": [
    "Mavridis IN",
    "Rodrigues D"
   ],
   "journal": "Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery",
   "year": "2021",
   "volume": "37",
   "pages": "367-374",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33717247",
   "doi": "10.3892/etm.2021.9735",
   "title": "Prenatal diagnosis of a pure 15q distal trisomy derived from a maternal pericentric inversion: A case report",
   "authors": [
    "Burada F",
    "Streata I",
    "Ungureanu A",
    "et al."
   ],
   "journal": "Experimental and therapeutic medicine",
   "year": "2021",
   "volume": "21",
   "pages": "304",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33369153",
   "doi": "10.1002/ajmg.a.62033",
   "title": "Prevalence and risk factors of radial ray deficiencies: A population-based case-control study",
   "authors": [
    "Syvänen J",
    "Raitio A",
    "Helenius I",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2021",
   "volume": "185",
   "pages": "759-765",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93321"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34507670",
   "doi": "10.1016/j.tjog.2021.07.020",
   "title": "Rapid diagnosis of trisomy 13 of maternal origin by quantitative fluorescent polymerase chain reaction analysis in a pregnancy with fetal holoprosencephaly, premaxillary agenesis, postaxial polydactyly of left hand and overriding aorta",
   "authors": [
    "Chen CP",
    "Wu CY",
    "Chern SR",
    "et al."
   ],
   "journal": "Taiwanese journal of obstetrics & gynecology",
   "year": "2021",
   "volume": "60",
   "pages": "903-904",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33509875",
   "doi": "10.1136/bcr-2020-238392",
   "title": "Reinforcing the vascular disruption theory of the genesis of Poland's syndrome: a rare association of diaphragmatic eventration in a preterm infant with severe musculoskeletal defects",
   "authors": [
    "Shahrul Baharin N",
    "Awadh Hashim E",
    "Bin Huey Q",
    "et al."
   ],
   "journal": "BMJ case reports",
   "year": "2021",
   "volume": "14",
   "pages": "",
   "pubtypes": [
    "Case Reports",
    "Video-Audio Media"
   ],
   "codes": [
    "1570",
    "2911"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32991492",
   "doi": "10.1097/BPO.0000000000001686",
   "title": "Risk Factors and Prevalence of Limb Deficiencies Associated With Amniotic Band Sequence: A Population-based Case-control Study",
   "authors": [
    "Syvänen J",
    "Raitio A",
    "Nietosvaara Y",
    "et al."
   ],
   "journal": "Journal of pediatric orthopedics",
   "year": "2021",
   "volume": "41",
   "pages": "e94-e97",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34275566",
   "doi": "10.1016/j.jocn.2021.06.015",
   "title": "Split hand in amyotrophic lateral sclerosis: A systematic review and meta-analysis",
   "authors": [
    "Hu N",
    "Wang J",
    "Liu M"
   ],
   "journal": "Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia",
   "year": "2021",
   "volume": "90",
   "pages": "293-301",
   "pubtypes": [
    "Meta-Analysis",
    "Systematic Review"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33791682",
   "doi": "10.1016/j.xhgg.2020.100016",
   "title": "TMEM218 dysfunction causes ciliopathies, including Joubert and Meckel syndromes",
   "authors": [
    "Van De Weghe JC",
    "Giordano JL",
    "Mathijssen IB",
    "et al."
   ],
   "journal": "HGG advances",
   "year": "2021",
   "volume": "2",
   "pages": "",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33763605",
   "doi": "10.1016/j.bbrep.2021.100978",
   "title": "Thalidomide affects limb formation and multiple myeloma related genes in human induced pluripotent stem cells and their mesoderm differentiation",
   "authors": [
    "Shimizu M",
    "Tachikawa S",
    "Saitoh N",
    "et al."
   ],
   "journal": "Biochemistry and biophysics reports",
   "year": "2021",
   "volume": "26",
   "pages": "100978",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33470442",
   "doi": "10.15252/embj.2020105375",
   "title": "Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF",
   "authors": [
    "Yamanaka S",
    "Murai H",
    "Saito D",
    "et al."
   ],
   "journal": "The EMBO journal",
   "year": "2021",
   "volume": "40",
   "pages": "e105375",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34586274",
   "doi": "10.1590/1413-81232021269.19462020",
   "title": "Thalidomide control and use: are these appropriate to extend the use and mitigate the risk of teratogenicity in Brazil?",
   "authors": [
    "Campos FT",
    "Santos RMMD",
    "Costa JP",
    "et al."
   ],
   "journal": "Ciencia & saude coletiva",
   "year": "2021",
   "volume": "26",
   "pages": "4233-4242",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "34522548",
   "doi": "10.7759/cureus.17070",
   "title": "Thalidomide-Then and Now: Case Report of a Woman With Thalidomide Embryopathy and Review of Current Thalidomide Uses",
   "authors": [
    "Malik S",
    "Cohen PR"
   ],
   "journal": "Cureus",
   "year": "2021",
   "volume": "13",
   "pages": "e17070",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "33480066",
   "doi": "10.1002/pd.5907",
   "title": "The prognosis of common arterial trunk from a fetal perspective: A prenatal cohort study and systematic literature review",
   "authors": [
    "van Nisselrooij AEL",
    "Herling L",
    "Clur SA",
    "et al."
   ],
   "journal": "Prenatal diagnosis",
   "year": "2021",
   "volume": "41",
   "pages": "754-765",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "974"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "33121298",
   "doi": "10.1177/1753193420967527",
   "title": "The psychosocial impact of congenital hand and upper limb differences on children: a qualitative study",
   "authors": [
    "McDougall L",
    "Kennedy J",
    "Coombs C",
    "et al."
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2021",
   "volume": "46",
   "pages": "391-397",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "living"
   ],
   "notes": [
    "published on the website of Aussiehands (Australia)"
   ],
   "via": [
    "Aussiehands (Australia)"
   ]
  },
  {
   "pmid": "32591344",
   "doi": "10.1136/jmedgenet-2020-106948",
   "title": "Variant type and position predict two distinct limb phenotypes in patients with GLI3-mediated polydactyly syndromes",
   "authors": [
    "Baas M",
    "Burger EB",
    "van den Ouweland AM",
    "et al."
   ],
   "journal": "Journal of medical genetics",
   "year": "2021",
   "volume": "58",
   "pages": "362-368",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "34202629",
   "doi": "10.3390/genes12070962",
   "title": "Whole Exome Sequencing Is the Minimal Technological Approach in Probands Born to Consanguineous Couples",
   "authors": [
    "Peluso F",
    "Caraffi SG",
    "Zuntini R",
    "et al."
   ],
   "journal": "Genes",
   "year": "2021",
   "volume": "12",
   "pages": "",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440",
    "2913"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "33915582",
   "doi": "10.1055/a-1457-2846",
   "title": "[Chronic Pain in People Impaired by Thalidomide Embryopathy: An Explorative Analysis of Prevalence, Pain Parameters and Biopsychosocial Factors]",
   "authors": [
    "Niecke A",
    "Ramesh I",
    "Albus C",
    "et al."
   ],
   "journal": "Psychotherapie, Psychosomatik, medizinische Psychologie",
   "year": "2021",
   "volume": "71",
   "pages": "370-380",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32992402",
   "doi": "10.1055/a-1250-8957",
   "title": "[Prenatal Diagnostics and Postnatal Complications in a Case of Extremely Rare Tetra-Amelia]",
   "authors": [
    "Schwickert A",
    "Dame C",
    "Akanbi S",
    "et al."
   ],
   "journal": "Zeitschrift fur Geburtshilfe und Neonatologie",
   "year": "2021",
   "volume": "225",
   "pages": "279-282",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "1027",
    "3301"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "34549573",
   "doi": "10.19191/EP21.4.P302.087",
   "title": "[Thalidomide and unilateral limb defects: the Italian chapter of a neverending story]",
   "authors": [
    "Terracini B"
   ],
   "journal": "Epidemiologia e prevenzione",
   "year": "2021",
   "volume": "45",
   "pages": "302-309",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32215516",
   "doi": "10.1590/S0104-59702020000100002",
   "title": "\"Risk-free rest and sleep:\" Jornal do Médico (Portugal) and the thalidomide disaster, 1960-1962",
   "authors": [
    "Leandro JA"
   ],
   "journal": "Historia, ciencias, saude--Manguinhos",
   "year": "2020",
   "volume": "27",
   "pages": "15-32",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31395945",
   "doi": "10.1038/s41436-019-0626-7",
   "title": "A novel ZRS variant causes preaxial polydactyly type I by increased sonic hedgehog expression in the developing limb bud",
   "authors": [
    "Xu C",
    "Yang X",
    "Zhou H",
    "et al."
   ],
   "journal": "Genetics in medicine : official journal of the American College of Medical Genetics",
   "year": "2020",
   "volume": "22",
   "pages": "189-198",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32286743",
   "doi": "10.1002/bdr2.1676",
   "title": "A novel biallelic splice-site variant in the LRP4 gene causes sclerosteosis 2",
   "authors": [
    "Bukowska-Olech E",
    "Sowińska-Seidler A",
    "Szczałuba K",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2020",
   "volume": "112",
   "pages": "652-659",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "3258",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32444984",
   "doi": "10.1007/s00415-020-09913-1",
   "title": "A systematic review and meta-analyses of pregnancy and fetal outcomes in women with multiple sclerosis: a contribution from the IMI2 ConcePTION project",
   "authors": [
    "Lopez-Leon S",
    "Geissbühler Y",
    "Sabidó M",
    "et al."
   ],
   "journal": "Journal of neurology",
   "year": "2020",
   "volume": "267",
   "pages": "2721-2731",
   "pubtypes": [
    "Meta-Analysis",
    "Systematic Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30857895",
   "doi": "10.1016/j.jht.2018.11.001",
   "title": "A systematic review of the use of psychological assessment tools in congenital upper limb anomaly management",
   "authors": [
    "Miller R",
    "Samarendra H",
    "Hotton M"
   ],
   "journal": "Journal of hand therapy : official journal of the American Society of Hand Therapists",
   "year": "2020",
   "volume": "33",
   "pages": "2-12.e1",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31972725",
   "doi": "10.1097/BPO.0000000000001510",
   "title": "Amputation Versus Limb Reconstruction for Fibula Hemimelia: A Meta-analysis",
   "authors": [
    "Elmherig A",
    "Ahmed AF",
    "Hegazy A",
    "et al."
   ],
   "journal": "Journal of pediatric orthopedics",
   "year": "2020",
   "volume": "40",
   "pages": "425-430",
   "pubtypes": [
    "Meta-Analysis",
    "Systematic Review"
   ],
   "codes": [
    "93323"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32051525",
   "doi": "10.1038/s41598-020-59455-9",
   "title": "An ENU-induced mutation in Twist1 transactivation domain causes hindlimb polydactyly with complete penetrance and dominant-negatively impairs E2A-dependent transcription",
   "authors": [
    "Chen RZ",
    "Cheng X",
    "Tan Y",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2020",
   "volume": "10",
   "pages": "2501",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32416360",
   "doi": "10.1016/j.envres.2020.109643",
   "title": "Association between maternal exposure to PM(10) and polydactyly and syndactyly: A population-based case-control study in Liaoning province, China",
   "authors": [
    "Zhang JY",
    "Gong TT",
    "Huang YH",
    "et al."
   ],
   "journal": "Environmental research",
   "year": "2020",
   "volume": "187",
   "pages": "109643",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31964914",
   "doi": "10.1038/s41598-020-57512-x",
   "title": "CRL4-Cereblon complex in Thalidomide Embryopathy: a translational investigation",
   "authors": [
    "Kowalski TW",
    "Gomes JDA",
    "Garcia GBC",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2020",
   "volume": "10",
   "pages": "851",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32758259",
   "doi": "10.1186/s13023-020-01481-x",
   "title": "Consensus based recommendations for diagnosis and medical management of Poland syndrome (sequence)",
   "authors": [
    "Baldelli I",
    "Baccarani A",
    "Barone C",
    "et al."
   ],
   "journal": "Orphanet journal of rare diseases",
   "year": "2020",
   "volume": "15",
   "pages": "201",
   "pubtypes": [
    "Consensus Statement",
    "Review"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "living",
    "review"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy), PiP UK (United Kingdom)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)",
    "PiP UK (United Kingdom)"
   ]
  },
  {
   "pmid": "31789838",
   "doi": "10.1097/DAD.0000000000001579",
   "title": "Fragmented Elastic Fibers in Focal Dermal Hypoplasia (Goltz-Gorlin Syndrome) Without Focal Dermal Hypoplasia: Report of a Male Case and Review of the Literature",
   "authors": [
    "Rohdenburg C",
    "Liersch J",
    "Kutsche K",
    "et al."
   ],
   "journal": "The American Journal of dermatopathology",
   "year": "2020",
   "volume": "42",
   "pages": "653-661",
   "pubtypes": [
    "Case Reports",
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32848052",
   "doi": "10.1073/pnas.1917701117",
   "title": "Hypnotic effect of thalidomide is independent of teratogenic ubiquitin/proteasome pathway",
   "authors": [
    "Hirose Y",
    "Kitazono T",
    "Sezaki M",
    "et al."
   ],
   "journal": "Proceedings of the National Academy of Sciences of the United States of America",
   "year": "2020",
   "volume": "117",
   "pages": "23106-23112",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32877749",
   "doi": "10.1016/j.bbadis.2020.165955",
   "title": "In ovo hyperglycemia causes congenital limb defects in chicken embryos via disruption of cell proliferation and apoptosis",
   "authors": [
    "Ding Z",
    "Zhou H",
    "McCauley N",
    "et al."
   ],
   "journal": "Biochimica et biophysica acta. Molecular basis of disease",
   "year": "2020",
   "volume": "1866",
   "pages": "165955",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, U.S. Gov't, Non-P.H.S."
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32880193",
   "doi": "10.1177/1071100720943850",
   "title": "Lateral Versus Medial Hallux Excision in Preaxial Polydactyly of the Foot",
   "authors": [
    "Burger EB",
    "Bus SA",
    "Hovius SER",
    "et al."
   ],
   "journal": "Foot & ankle international",
   "year": "2020",
   "volume": "41",
   "pages": "1553-1562",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "31913886",
   "doi": "10.1097/SAP.0000000000002202",
   "title": "Letter to the Editor: Response to Manzano Surroca et al. \"Poland Sequence: Retrospective Analysis of 66 Cases.\" Annals of Plastic Surgery, May 2019",
   "authors": [
    "Baldelli I",
    "Vappiani M",
    "Santori G",
    "et al."
   ],
   "journal": "Annals of plastic surgery",
   "year": "2020",
   "volume": "84",
   "pages": "341-342",
   "pubtypes": [
    "Comment",
    "Letter"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "32446860",
   "doi": "10.1016/j.yexmp.2020.104471",
   "title": "Maternal mosaicism underlies the inheritance of a rare germline AKT3 variant which is responsible for megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome in two Roma half-siblings",
   "authors": [
    "Szalai R",
    "Melegh BI",
    "Till A",
    "et al."
   ],
   "journal": "Experimental and molecular pathology",
   "year": "2020",
   "volume": "115",
   "pages": "104471",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30856359",
   "doi": "10.1080/14767058.2019.1593358",
   "title": "Maternal occupational exposure to chemicals in the textile factory during pregnancy is associated with a higher risk of polydactyly in the offspring",
   "authors": [
    "Shi J",
    "Lv ZT",
    "Lei Y",
    "et al."
   ],
   "journal": "The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians",
   "year": "2020",
   "volume": "33",
   "pages": "3935-3941",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32414180",
   "doi": "10.3390/ph13050095",
   "title": "Molecular Mechanisms of the Teratogenic Effects of Thalidomide",
   "authors": [
    "Asatsuma-Okumura T",
    "Ito T",
    "Handa H"
   ],
   "journal": "Pharmaceuticals (Basel, Switzerland)",
   "year": "2020",
   "volume": "13",
   "pages": "",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32016944",
   "doi": "10.1055/s-0039-3402009",
   "title": "Poland Syndrome with Atypical Malformations Associated to a de novo 1.5 Mb Xp22.31 Duplication",
   "authors": [
    "Massimino CR",
    "Smilari P",
    "Greco F",
    "et al."
   ],
   "journal": "Neuropediatrics",
   "year": "2020",
   "volume": "51",
   "pages": "359-363",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "31969401",
   "doi": "10.1136/bcr-2019-231345",
   "title": "Poor balance, bilateral upper limb phocomelia, no previous exercise: a challenging combination for fall prevention in a middle-aged thalidomide survivor",
   "authors": [
    "Morrison D"
   ],
   "journal": "BMJ case reports",
   "year": "2020",
   "volume": "13",
   "pages": "",
   "pubtypes": [
    "Case Reports",
    "Video-Audio Media"
   ],
   "codes": [
    "2879",
    "93321",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32335054",
   "doi": "10.1016/j.ajog.2020.04.016",
   "title": "Prevalence, risk factors, and outcome of postprocedural amniotic band disruption sequence after fetoscopic laser surgery in twin-twin transfusion syndrome: a large single-center case series",
   "authors": [
    "Knijnenburg PJC",
    "Slaghekke F",
    "Tollenaar LSA",
    "et al."
   ],
   "journal": "American journal of obstetrics and gynecology",
   "year": "2020",
   "volume": "223",
   "pages": "576.e1-576.e8",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32893502",
   "doi": "10.1002/mgg3.1464",
   "title": "Quality of life and pain in patients with thalidomide embryopathy in Japan",
   "authors": [
    "Imai K",
    "Sone H",
    "Otomo K",
    "et al."
   ],
   "journal": "Molecular genetics & genomic medicine",
   "year": "2020",
   "volume": "8",
   "pages": "e1464",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32304852",
   "doi": "10.1016/j.biopha.2020.110114",
   "title": "Recent advances in the molecular mechanism of thalidomide teratogenicity",
   "authors": [
    "Gao S",
    "Wang S",
    "Fan R",
    "et al."
   ],
   "journal": "Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie",
   "year": "2020",
   "volume": "127",
   "pages": "110114",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31965514",
   "doi": "10.1007/s11604-020-00920-w",
   "title": "Skeletal ciliopathies: a pattern recognition approach",
   "authors": [
    "Handa A",
    "Voss U",
    "Hammarsjö A",
    "et al."
   ],
   "journal": "Japanese journal of radiology",
   "year": "2020",
   "volume": "38",
   "pages": "193-206",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "genetics",
    "review"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "32727553",
   "doi": "10.1186/s13071-020-04256-2",
   "title": "Strigea robusta causes polydactyly and severe forms of Rostand's anomaly P in water frogs",
   "authors": [
    "Svinin AO",
    "Bashinskiy IV",
    "Litvinchuk SN",
    "et al."
   ],
   "journal": "Parasites & vectors",
   "year": "2020",
   "volume": "13",
   "pages": "381",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32000609",
   "doi": "10.1142/S2424835520300017",
   "title": "Surgical Treatment and Outcomes of Syndactyly: A Systematic Review",
   "authors": [
    "Mende K",
    "Watson A",
    "Stewart DA"
   ],
   "journal": "The journal of hand surgery Asian-Pacific volume",
   "year": "2020",
   "volume": "25",
   "pages": "1-12",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32574274",
   "doi": "10.3389/fimmu.2020.01248",
   "title": "Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing?",
   "authors": [
    "Khalil A",
    "Kamar A",
    "Nemer G"
   ],
   "journal": "Frontiers in immunology",
   "year": "2020",
   "volume": "11",
   "pages": "1248",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32080096",
   "doi": "10.1097/MD.0000000000019169",
   "title": "The splice c.1815G>A variant in KIAA0586 results in a phenotype bridging short-rib-polydactyly and oral-facial-digital syndrome: A case report and literature review",
   "authors": [
    "Cocciadiferro D",
    "Agolini E",
    "Digilio MC",
    "et al."
   ],
   "journal": "Medicine",
   "year": "2020",
   "volume": "99",
   "pages": "e19169",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "genetics",
    "review"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "30417703",
   "doi": "10.1177/1558944718810885",
   "title": "To Tie or Not to Tie: A Systematic Review of Postaxial Polydactyly and Outcomes of Suture Ligation Versus Surgical Excision",
   "authors": [
    "Chopan M",
    "Sayadi L",
    "Chim H",
    "et al."
   ],
   "journal": "Hand (New York, N.Y.)",
   "year": "2020",
   "volume": "15",
   "pages": "303-310",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "32179704",
   "doi": "10.1136/jmedgenet-2019-106685",
   "title": "Variable expression of subclinical phenotypes instead of reduced penetrance in families with mild triphalangeal thumb phenotypes",
   "authors": [
    "Potuijt JWP",
    "Hoogeboom J",
    "de Graaff E",
    "et al."
   ],
   "journal": "Journal of medical genetics",
   "year": "2020",
   "volume": "57",
   "pages": "660-663",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "published on the website of ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ],
   "via": [
    "ERN [ITHACA] - ILIAD Rare Diseases patient registry: an International Library of Intellectual disability and Anomalies of Development (France)"
   ]
  },
  {
   "pmid": "31840411",
   "doi": "10.1111/jcmm.14887",
   "title": "Whole exome sequencing identified a homozygous novel variant in CEP290 gene causes Meckel syndrome",
   "authors": [
    "Zhang R",
    "Chen S",
    "Han P",
    "et al."
   ],
   "journal": "Journal of cellular and molecular medicine",
   "year": "2020",
   "volume": "24",
   "pages": "1906-1916",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31814667",
   "doi": "10.1055/s-0038-1669364",
   "title": "A Case of Nonsyndromic Unilateral Cleft Hand with Central Polydactyly, Syndactyly, and Thumb Hypoplasia: Support for a Common Etiology",
   "authors": [
    "Duran A",
    "Buyukdogan H"
   ],
   "journal": "Journal of hand and microsurgery",
   "year": "2019",
   "volume": "11",
   "pages": "154-156",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2440",
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30562203",
   "doi": "10.1097/SAP.0000000000001685",
   "title": "A Novel Frameshift Mutation of GLI3 Causes Isolated Postaxial Polydactyly",
   "authors": [
    "Ni F",
    "Han G",
    "Guo R",
    "et al."
   ],
   "journal": "Annals of plastic surgery",
   "year": "2019",
   "volume": "82",
   "pages": "570-573",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30253685",
   "doi": "10.1177/1753193418800631",
   "title": "A clinical review and introduction of the diagnostic algorithm for thalidomide embryopathy (DATE)",
   "authors": [
    "Mansour S",
    "Baple E",
    "Hall CM"
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2019",
   "volume": "44",
   "pages": "96-108",
   "pubtypes": [
    "Historical Article",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31339667",
   "doi": "10.1002/bdr2.1558",
   "title": "A nationwide survey regarding the life situations of patients with thalidomide embryopathy in Japan, 2018: First report",
   "authors": [
    "Hinoshita F",
    "Beppu H",
    "Shioji S",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2019",
   "volume": "111",
   "pages": "1633-1642",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "30787447",
   "doi": "10.1038/s41431-019-0350-4",
   "title": "A novel dominant-negative FGFR1 variant causes Hartsfield syndrome by deregulating RAS/ERK1/2 pathway",
   "authors": [
    "Palumbo P",
    "Petracca A",
    "Maggi R",
    "et al."
   ],
   "journal": "European journal of human genetics : EJHG",
   "year": "2019",
   "volume": "27",
   "pages": "1113-1120",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31221518",
   "doi": "10.1016/j.jhsa.2019.04.013",
   "title": "Analysis of Causes for Congenital Ulnar Deviated Thumbs at the Distal Phalanx Level in 157 Thumbs",
   "authors": [
    "Tian X",
    "Chan P",
    "Li A",
    "et al."
   ],
   "journal": "The Journal of hand surgery",
   "year": "2019",
   "volume": "44",
   "pages": "860-867",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30137461",
   "doi": "10.1093/pubmed/fdy137",
   "title": "Association between early prenatal exposure to ambient air pollution and birth defects: evidence from newborns in Xi'an, China",
   "authors": [
    "Wang L",
    "Xiang X",
    "Mi B",
    "et al."
   ],
   "journal": "Journal of public health (Oxford, England)",
   "year": "2019",
   "volume": "41",
   "pages": "494-501",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31649809",
   "doi": "10.1186/s13229-019-0286-0",
   "title": "Disruption of PHF21A causes syndromic intellectual disability with craniofacial anomalies, epilepsy, hypotonia, and neurobehavioral problems including autism",
   "authors": [
    "Kim HG",
    "Rosenfeld JA",
    "Scott DA",
    "et al."
   ],
   "journal": "Molecular autism",
   "year": "2019",
   "volume": "10",
   "pages": "35",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31314783",
   "doi": "10.1371/journal.pone.0219930",
   "title": "Epidemiology of limb reduction defects as registered in the Medical Birth Registry of Norway, 1970-2016: Population based study",
   "authors": [
    "Klungsøyr K",
    "Nordtveit TI",
    "Kaastad TS",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2019",
   "volume": "14",
   "pages": "e0219930",
   "pubtypes": [
    "Historical Article",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "Norway, limb reduction defects 1970-2016"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "31753026",
   "doi": "10.1186/s13023-019-1253-8",
   "title": "Experiences of patients with Poland syndrome of diagnosis and care in Italy: a pilot survey",
   "authors": [
    "Baldelli I",
    "Gallo F",
    "Crimi M",
    "et al."
   ],
   "journal": "Orphanet journal of rare diseases",
   "year": "2019",
   "volume": "14",
   "pages": "269",
   "pubtypes": [],
   "codes": [
    "2911"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "31181251",
   "doi": "10.1016/j.reprotox.2019.05.066",
   "title": "Fetal methotrexate syndrome: A systematic review of case reports",
   "authors": [
    "Verberne EA",
    "de Haan E",
    "van Tintelen JP",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "2019",
   "volume": "87",
   "pages": "125-139",
   "pubtypes": [
    "Case Reports",
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30887706",
   "doi": "10.1002/bdr2.1493",
   "title": "HSPA6: A new autosomal recessive candidate gene for the VATER/VACTERL malformation spectrum",
   "authors": [
    "Kause F",
    "Zhang R",
    "Ludwig M",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2019",
   "volume": "111",
   "pages": "591-597",
   "pubtypes": [
    "Case Reports",
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93321"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ]
  },
  {
   "pmid": "30943953",
   "doi": "10.1186/s12905-019-0745-y",
   "title": "Life situation of women impaired by Thalidomide embryopathy in North Rhine-Westphalia - a comparative analysis of a recent cross-sectional study with earlier data",
   "authors": [
    "Samel C",
    "Albus C",
    "Nippert I",
    "et al."
   ],
   "journal": "BMC women's health",
   "year": "2019",
   "volume": "19",
   "pages": "51",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30589520",
   "doi": "10.1002/bdr2.1442",
   "title": "Limb body wall complex: Its delineation and relationship with amniotic bands using clustering methods",
   "authors": [
    "Rittler M",
    "Campaña H",
    "Poletta FA",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2019",
   "volume": "111",
   "pages": "222-228",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "1027",
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30969202",
   "doi": "10.1097/AOG.0000000000003235",
   "title": "Managing a Pregnancy With Maternal Amelia",
   "authors": [
    "Siwatch S",
    "Gainder S",
    "Prasad GRV",
    "et al."
   ],
   "journal": "Obstetrics and gynecology",
   "year": "2019",
   "volume": "133",
   "pages": "971-974",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "1027",
    "2879"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31546130",
   "doi": "10.1016/j.envres.2019.108716",
   "title": "Maternal exposure to outdoor air pollution and congenital limb deficiencies in the National Birth Defects Prevention Study",
   "authors": [
    "Choi G",
    "Stingone JA",
    "Desrosiers TA",
    "et al."
   ],
   "journal": "Environmental research",
   "year": "2019",
   "volume": "179",
   "pages": "108716",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "31325247",
   "doi": "10.1002/mgg3.878",
   "title": "Novel GLI3 variant causes Greig cephalopolysyndactyly syndrome in three generations of a Lithuanian family",
   "authors": [
    "Siavrienė E",
    "Mikštienė V",
    "Radzevičius D",
    "et al."
   ],
   "journal": "Molecular genetics & genomic medicine",
   "year": "2019",
   "volume": "7",
   "pages": "e878",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30869735",
   "doi": "10.1127/anthranz/2019/0981",
   "title": "Reference tables with centiles of limb to body height ratios of healthy human adults for assessing potential thalidomide embryopathy",
   "authors": [
    "Reimann A",
    "Beyer R",
    "Mumm R",
    "et al."
   ],
   "journal": "Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur",
   "year": "2019",
   "volume": "76",
   "pages": "391-400",
   "pubtypes": [],
   "codes": [
    "1027",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30650111",
   "doi": "10.1371/journal.pone.0210222",
   "title": "The health and quality of life of Thalidomide survivors as they age - Evidence from a UK survey",
   "authors": [
    "Newbronner E",
    "Glendinning C",
    "Atkin K",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2019",
   "volume": "14",
   "pages": "e0210222",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "31388035",
   "doi": "10.1038/s41598-019-47739-8",
   "title": "The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis",
   "authors": [
    "Gomes JDA",
    "Kowalski TW",
    "Fraga LR",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2019",
   "volume": "9",
   "pages": "11413",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30335598",
   "doi": "10.1177/1753193418805249",
   "title": "The teratogenic effects of thalidomide on limbs",
   "authors": [
    "Vargesson N"
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2019",
   "volume": "44",
   "pages": "88-95",
   "pubtypes": [
    "Historical Article",
    "Review"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30887894",
   "doi": "10.1024/1012-5302/a000670",
   "title": "[Upcoming challenges in providing care for thalidomide impaired individuals]",
   "authors": [
    "Samel C",
    "Albus C",
    "Tebest R",
    "et al."
   ],
   "journal": "Pflege",
   "year": "2019",
   "volume": "32",
   "pages": "137-145",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "31591562",
   "doi": "10.1038/s41589-019-0366-7",
   "title": "p63 is a cereblon substrate involved in thalidomide teratogenicity",
   "authors": [
    "Asatsuma-Okumura T",
    "Ando H",
    "De Simone M",
    "et al."
   ],
   "journal": "Nature chemical biology",
   "year": "2019",
   "volume": "15",
   "pages": "1077-1084",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of V.I.TA – Vittime Talidomide Italia (Italy)"
   ],
   "via": [
    "PubMed search",
    "V.I.TA – Vittime Talidomide Italia (Italy)"
   ]
  },
  {
   "pmid": "30047505",
   "doi": "10.1253/circj.CJ-18-0775",
   "title": "A Lesson From the Thalidomide Tragedy　- The Past Is Never Dead. It's Not Even Past. William Faulkner, From \"Requiem for a Nun\"",
   "authors": [
    "Yashiro K",
    "Miyagawa S",
    "Sawa Y"
   ],
   "journal": "Circulation journal : official journal of the Japanese Circulation Society",
   "year": "2018",
   "volume": "82",
   "pages": "2250-2252",
   "pubtypes": [
    "Comment",
    "Editorial"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29265343",
   "doi": "10.1111/ijd.13862",
   "title": "A novel homozygous mutation in PVRL4 causes ectodermal dysplasia-syndactyly syndrome 1",
   "authors": [
    "Florian R",
    "Gruber R",
    "Volc-Platzer B"
   ],
   "journal": "International journal of dermatology",
   "year": "2018",
   "volume": "57",
   "pages": "223-226",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30419059",
   "doi": "10.1371/journal.pone.0207067",
   "title": "A systematic review on the impact of gestational Lyme disease in humans on the fetus and newborn",
   "authors": [
    "Waddell LA",
    "Greig J",
    "Lindsay LR",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2018",
   "volume": "13",
   "pages": "e0207067",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29998932",
   "doi": "10.1253/circj.CJ-18-0414",
   "title": "Assessment of Congenital Vascular and Organ Anomalies in Subjects With Thalidomide Embryopathy Using Non-Contrast Magnetic Resonance Angiography",
   "authors": [
    "Weinrich JM",
    "Beyer R",
    "Well L",
    "et al."
   ],
   "journal": "Circulation journal : official journal of the Japanese Circulation Society",
   "year": "2018",
   "volume": "82",
   "pages": "2364-2371",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29377643",
   "doi": "10.1002/bdr2.1105",
   "title": "Causes of Congenital Malformations",
   "authors": [
    "Toufaily MH",
    "Westgate MN",
    "Lin AE",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2018",
   "volume": "110",
   "pages": "87-91",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29292497",
   "doi": "10.1002/1873-3468.12963",
   "title": "Disruption of Wnt production in Shh lineage causes bone malformation in mice, mimicking human Malik-Percin-type syndactyly",
   "authors": [
    "Zhu XJ",
    "Fang Y",
    "Xiong Y",
    "et al."
   ],
   "journal": "FEBS letters",
   "year": "2018",
   "volume": "592",
   "pages": "356-368",
   "pubtypes": [
    "Letter",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29193903",
   "doi": "10.1002/bdr2.1163",
   "title": "Genetic susceptibility to thalidomide embryopathy in humans: Study of candidate development genes",
   "authors": [
    "Gomes JDA",
    "Kowalski TW",
    "Fraga LR",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2018",
   "volume": "110",
   "pages": "456-461",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29377641",
   "doi": "10.1002/bdr2.1160",
   "title": "Malformations attributed to the process of vascular disruption",
   "authors": [
    "Holmes LB",
    "Westgate MN",
    "Nasri H",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2018",
   "volume": "110",
   "pages": "98-107",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "295000",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29159873",
   "doi": "10.1002/ajmg.a.38545",
   "title": "Orthopaedic manifestations within the 22q11.2 Deletion syndrome: A systematic review",
   "authors": [
    "Homans JF",
    "Tromp IN",
    "Colo D",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2018",
   "volume": "176",
   "pages": "2104-2120",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Systematic Review"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30078491",
   "doi": "10.1053/j.sempedsurg.2018.05.007",
   "title": "Poland syndrome: A proposed classification system and perspectives on diagnosis and treatment",
   "authors": [
    "Romanini MV",
    "Calevo MG",
    "Puliti A",
    "et al."
   ],
   "journal": "Seminars in pediatric surgery",
   "year": "2018",
   "volume": "27",
   "pages": "189-199",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "29384817",
   "doi": "10.1097/PRS.0000000000004301",
   "title": "Postoperative Patient- and Parent-Reported Outcomes for Children with Congenital Hand Differences: A Systematic Review",
   "authors": [
    "Farr S"
   ],
   "journal": "Plastic and reconstructive surgery",
   "year": "2018",
   "volume": "141",
   "pages": "784e-785e",
   "pubtypes": [
    "Comment",
    "Letter"
   ],
   "codes": [],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30024522",
   "doi": "10.1097/MD.0000000000011471",
   "title": "Prenatal limb defects: Epidemiologic characteristics and an epidemiologic analysis of risk factors",
   "authors": [
    "Shi Y",
    "Zhang B",
    "Kong F",
    "et al."
   ],
   "journal": "Medicine",
   "year": "2018",
   "volume": "97",
   "pages": "e11471",
   "pubtypes": [
    "Observational Study"
   ],
   "codes": [
    "2440",
    "2879",
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29384815",
   "doi": "10.1097/PRS.0000000000004302",
   "title": "Reply: Postoperative Patient- and Parent-Reported Outcomes for Children with Congenital Hand Differences: A Systematic Review",
   "authors": [
    "Adkinson JM"
   ],
   "journal": "Plastic and reconstructive surgery",
   "year": "2018",
   "volume": "141",
   "pages": "785e",
   "pubtypes": [
    "Comment",
    "Letter"
   ],
   "codes": [],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30190590",
   "doi": "10.1038/s41589-018-0129-x",
   "title": "SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate",
   "authors": [
    "Matyskiela ME",
    "Couto S",
    "Zheng X",
    "et al."
   ],
   "journal": "Nature chemical biology",
   "year": "2018",
   "volume": "14",
   "pages": "981-987",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29980223",
   "doi": "10.1186/s13256-018-1647-6",
   "title": "Semilobar holoprosencephaly with cebocephaly associated with maternal early onset preeclampsia: a case report",
   "authors": [
    "Essa AA",
    "Feleke LA",
    "Ahmed DM"
   ],
   "journal": "Journal of medical case reports",
   "year": "2018",
   "volume": "12",
   "pages": "207",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30597765",
   "doi": "10.1002/ajmg.a.61008",
   "title": "Thalidomide Teratogenic Effects Linked to Degradation of SALL4: After 60 years, researchers have now shed light on the mechanism underlying thalidomide's devastating teratogenic effects",
   "authors": [],
   "journal": "American journal of medical genetics. Part A",
   "year": "2018",
   "volume": "176",
   "pages": "2538-2539",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "30542600",
   "doi": "10.1039/c8tx00187a",
   "title": "Thalidomide-type teratogenicity: structure-activity relationships for congeners",
   "authors": [
    "Smith RL",
    "Mitchell SC"
   ],
   "journal": "Toxicology research",
   "year": "2018",
   "volume": "7",
   "pages": "1036-1047",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29109034",
   "doi": "10.1016/j.dhjo.2017.09.004",
   "title": "The changing health of Thalidomide survivors as they age: A scoping review",
   "authors": [
    "Newbronner E",
    "Atkin K"
   ],
   "journal": "Disability and health journal",
   "year": "2018",
   "volume": "11",
   "pages": "184-191",
   "pubtypes": [
    "Scoping Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living",
    "meta",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29621304",
   "doi": "10.1371/journal.pone.0194986",
   "title": "Trends in congenital anomalies in Europe from 1980 to 2012",
   "authors": [
    "Morris JK",
    "Springett AL",
    "Greenlees R",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2018",
   "volume": "13",
   "pages": "e0194986",
   "pubtypes": [
    "Historical Article",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ]
  },
  {
   "pmid": "30462958",
   "doi": "10.3760/cma.j.issn.0254-6450.2018.11.012",
   "title": "[Active and passive maternal smoking during pregnancy and risk of having a child with polydactyly: a case-control study]",
   "authors": [
    "Shi J",
    "Tian Y",
    "Lei Y",
    "et al."
   ],
   "journal": "Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi",
   "year": "2018",
   "volume": "39",
   "pages": "1482-1485",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28052826",
   "doi": "10.1016/j.jhsa.2016.11.006",
   "title": "A Systematic Review and Comparison of Outcomes Following Simple Syndactyly Reconstruction With Skin Grafts or a Dorsal Metacarpal Advancement Flap",
   "authors": [
    "Sullivan MA",
    "Adkinson JM"
   ],
   "journal": "The Journal of hand surgery",
   "year": "2017",
   "volume": "42",
   "pages": "34-40.e6",
   "pubtypes": [
    "Comparative Study",
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28130151",
   "doi": "10.1016/j.reprotox.2017.01.010",
   "title": "A new mammalian model system for thalidomide teratogenesis: Monodelphis domestica",
   "authors": [
    "Sorensen D",
    "Sackett A",
    "Urban DJ",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "2017",
   "volume": "70",
   "pages": "126-132",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29263794",
   "doi": "10.1038/hgv.2017.54",
   "title": "A novel homozygous missense mutation in BHLHA9 causes mesoaxial synostotic syndactyly with phalangeal reduction in a Pakistani family",
   "authors": [
    "Khan A",
    "Wang R",
    "Han S",
    "et al."
   ],
   "journal": "Human genome variation",
   "year": "2017",
   "volume": "4",
   "pages": "17054",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28160419",
   "doi": "10.1002/ajmg.a.37889",
   "title": "Adams-Oliver syndrome review of the literature: Refining the diagnostic phenotype",
   "authors": [
    "Hassed S",
    "Li S",
    "Mulvihill J",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2017",
   "volume": "173",
   "pages": "790-800",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "974"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "cited by Orphanet for Adams-Oliver syndrome (cases/families, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "28161597",
   "doi": "10.1016/j.reprotox.2017.01.012",
   "title": "Angiogenesis-related genes and thalidomide teratogenesis in humans: an approach on genetic variation and review of past in vitro studies",
   "authors": [
    "Kowalski TW",
    "Fraga LR",
    "Tovo-Rodrigues L",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "2017",
   "volume": "70",
   "pages": "133-140",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28846100",
   "doi": "10.1038/ng.3939",
   "title": "Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)",
   "authors": [
    "Will AJ",
    "Cova G",
    "Osterwalder M",
    "et al."
   ],
   "journal": "Nature genetics",
   "year": "2017",
   "volume": "49",
   "pages": "1539-1545",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27924730",
   "doi": "10.2174/1871520616666161206150421",
   "title": "Congenital Malformations Attributed to Prenatal Exposure to Cyclophosphamide",
   "authors": [
    "Rengasamy P"
   ],
   "journal": "Anti-cancer agents in medicinal chemistry",
   "year": "2017",
   "volume": "17",
   "pages": "1211-1227",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "93322"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29053644",
   "doi": "10.4317/medoral.21628",
   "title": "Dental approach for Apert syndrome in children: a systematic review",
   "authors": [
    "López-Estudillo AS",
    "Rosales-Bérber MA",
    "Ruiz-Rodríguez S",
    "et al."
   ],
   "journal": "Medicina oral, patologia oral y cirugia bucal",
   "year": "2017",
   "volume": "22",
   "pages": "e660-e668",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28123099",
   "doi": "10.1093/toxsci/kfx019",
   "title": "From the Cover: Teratogenic Effects of in Utero Exposure to Di-(2-Ethylhexyl)-Phthalate (DEHP) in B6:129S4 Mice",
   "authors": [
    "Ungewitter E",
    "Rotgers E",
    "Bantukul T",
    "et al."
   ],
   "journal": "Toxicological sciences : an official journal of the Society of Toxicology",
   "year": "2017",
   "volume": "157",
   "pages": "8-19",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28504423",
   "doi": "10.1002/bdr2.1026",
   "title": "Genetic vulnerabilities to prenatal alcohol exposure: Limb defects in sonic hedgehog and GLI2 heterozygous mice",
   "authors": [
    "Fish EW",
    "Murdaugh LB",
    "Sulik KK",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2017",
   "volume": "109",
   "pages": "860-865",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29053750",
   "doi": "10.1371/journal.pone.0186388",
   "title": "Middle-aged individuals with thalidomide embryopathy have undergone few surgical limb procedures and demonstrate a high degree of physical independence",
   "authors": [
    "Ghassemi Jahani SA",
    "Danielsson A",
    "Karlsson J",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2017",
   "volume": "12",
   "pages": "e0186388",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28559208",
   "doi": "10.1016/j.ejmg.2017.05.004",
   "title": "Novel splice mutation in LRP4 causes severe type of Cenani-Lenz syndactyly syndrome with oro-facial and skeletal symptoms",
   "authors": [
    "Afzal M",
    "Zaman Q",
    "Kornak U",
    "et al."
   ],
   "journal": "European journal of medical genetics",
   "year": "2017",
   "volume": "60",
   "pages": "421-425",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "3258",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28538570",
   "doi": "10.1097/PRS.0000000000003358",
   "title": "Postoperative Patient- and Parent-Reported Outcomes for Children with Congenital Hand Differences: A Systematic Review",
   "authors": [
    "Bickham RS",
    "Waljee JF",
    "Chung KC",
    "et al."
   ],
   "journal": "Plastic and reconstructive surgery",
   "year": "2017",
   "volume": "139",
   "pages": "1422-1429",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [
    "93321"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27801979",
   "doi": "10.1002/bdra.23571",
   "title": "Preaxial polydactyly following early gestational exposure to the smoothened agonist, SAG, in C57BL/6J mice",
   "authors": [
    "Fish EW",
    "Parnell SE",
    "Sulik KK",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2017",
   "volume": "109",
   "pages": "49-54",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28736902",
   "doi": "10.1002/jum.14295",
   "title": "Pseudoamniotic Band Syndrome After Fetoscopic Laser Ablation of Placental Anastomoses for Twin-Twin Transfusion Syndrome: Two Case Reports and Systematic Review",
   "authors": [
    "Lafitte AS",
    "Verspyck E",
    "Jeanne Pasquier C",
    "et al."
   ],
   "journal": "Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine",
   "year": "2017",
   "volume": "36",
   "pages": "2373-2377",
   "pubtypes": [
    "Case Reports",
    "Systematic Review"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28669420",
   "doi": "10.1016/j.jhsa.2017.04.012",
   "title": "Radial Longitudinal Deficiency: Recent Developments, Controversies, and an Evidence-Based Guide to Treatment",
   "authors": [
    "Colen DL",
    "Lin IC",
    "Levin LS",
    "et al."
   ],
   "journal": "The Journal of hand surgery",
   "year": "2017",
   "volume": "42",
   "pages": "546-563",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "93321"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "cited by Orphanet for Isolated radial hemimelia (point prevalence, Worldwide)",
    "cited by Orphanet for Isolated radial hemimelia (prevalence at birth, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "27659767",
   "doi": "10.1681/ASN.2015091029",
   "title": "Risk Factors for Severe Renal Disease in Bardet-Biedl Syndrome",
   "authors": [
    "Forsythe E",
    "Sparks K",
    "Best S",
    "et al."
   ],
   "journal": "Journal of the American Society of Nephrology : JASN",
   "year": "2017",
   "volume": "28",
   "pages": "963-970",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28486600",
   "doi": "10.1093/hmg/ddx183",
   "title": "Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling",
   "authors": [
    "Li J",
    "Lu D",
    "Liu H",
    "et al."
   ],
   "journal": "Human molecular genetics",
   "year": "2017",
   "volume": "26",
   "pages": "2949-2960",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28990356",
   "doi": "10.1002/bdr2.1124",
   "title": "Thalidomide Embryopathy as Possible Cause of Anterior Sacral Meningocele: A Case Report",
   "authors": [
    "Croci DM",
    "Dalolio M",
    "Schaeren S",
    "et al."
   ],
   "journal": "Birth defects research",
   "year": "2017",
   "volume": "109",
   "pages": "1390-1392",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28745489",
   "doi": "10.1021/acs.chemrestox.7b00127",
   "title": "The Dihydroxy Metabolite of the Teratogen Thalidomide Causes Oxidative DNA Damage",
   "authors": [
    "Wani TH",
    "Chakrabarty A",
    "Shibata N",
    "et al."
   ],
   "journal": "Chemical research in toxicology",
   "year": "2017",
   "volume": "30",
   "pages": "1622-1628",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28429672",
   "doi": "10.2174/1566524017666170331162315",
   "title": "The Molecular Mechanisms of Thalidomide Teratogenicity and Implications for Modern Medicine",
   "authors": [
    "Knobloch J",
    "Jungck D",
    "Koch A"
   ],
   "journal": "Current molecular medicine",
   "year": "2017",
   "volume": "17",
   "pages": "108-117",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27638330",
   "doi": "10.1016/j.ejmg.2016.09.015",
   "title": "The impact of thalidomide use in birth defects in Brazil",
   "authors": [
    "Sales Luiz Vianna F",
    "Kowalski TW",
    "Fraga LR",
    "et al."
   ],
   "journal": "European journal of medical genetics",
   "year": "2017",
   "volume": "60",
   "pages": "12-15",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "27739257",
   "doi": "10.1002/ajmg.a.38016",
   "title": "The prevalence of amnion rupture sequence, limb body wall defects and body wall defects in Alberta 1980-2012 with a review of risk factors and familial cases",
   "authors": [
    "Lowry RB",
    "Bedard T",
    "Sibbald B"
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2017",
   "volume": "173",
   "pages": "299-308",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "29019599",
   "doi": "10.1590/S0104-59702017000300004",
   "title": "The thalidomide tragedy: the struggle for victims' rights and improved pharmaceutical regulation",
   "authors": [
    "Moro A",
    "Invernizzi N"
   ],
   "journal": "Historia, ciencias, saude--Manguinhos",
   "year": "2017",
   "volume": "24",
   "pages": "603-622",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "26581570",
   "doi": "10.1002/ajmg.a.37464",
   "title": "A homozygous HOXD13 missense mutation causes a severe form of synpolydactyly with metacarpal to carpal transformation",
   "authors": [
    "Ibrahim DM",
    "Tayebi N",
    "Knaus A",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2016",
   "volume": "170",
   "pages": "615-21",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "26900326",
   "doi": "",
   "title": "A novel H395R mutation in MKKS/BBS6 causes retinitis pigmentosa and polydactyly without other findings of Bardet-Biedl or McKusick-Kaufman syndrome",
   "authors": [
    "Hulleman JD",
    "Nguyen A",
    "Ramprasad VL",
    "et al."
   ],
   "journal": "Molecular vision",
   "year": "2016",
   "volume": "22",
   "pages": "73-81",
   "pubtypes": [
    "Case Reports",
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27069622",
   "doi": "10.1186/s13630-016-0029-1",
   "title": "A novel ICK mutation causes ciliary disruption and lethal endocrine-cerebro-osteodysplasia syndrome",
   "authors": [
    "Oud MM",
    "Bonnard C",
    "Mans DA",
    "et al."
   ],
   "journal": "Cilia",
   "year": "2016",
   "volume": "5",
   "pages": "8",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27466187",
   "doi": "10.1093/hmg/ddw240",
   "title": "An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome",
   "authors": [
    "Paige Taylor S",
    "Kunova Bosakova M",
    "Varecha M",
    "et al."
   ],
   "journal": "Human molecular genetics",
   "year": "2016",
   "volume": "25",
   "pages": "3998-4011",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27884122",
   "doi": "10.1186/s12881-016-0351-x",
   "title": "Assessment of copy number variations in 120 patients with Poland syndrome",
   "authors": [
    "Vaccari CM",
    "Tassano E",
    "Torre M",
    "et al."
   ],
   "journal": "BMC medical genetics",
   "year": "2016",
   "volume": "17",
   "pages": "89",
   "pubtypes": [],
   "codes": [
    "2911"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "27443814",
   "doi": "10.1016/j.ajog.2016.07.022",
   "title": "Associations between maternal periconceptional exposure to secondhand tobacco smoke and major birth defects",
   "authors": [
    "Hoyt AT",
    "Canfield MA",
    "Romitti PA",
    "et al."
   ],
   "journal": "American journal of obstetrics and gynecology",
   "year": "2016",
   "volume": "215",
   "pages": "613.e1-613.e11",
   "pubtypes": [
    "Multicenter Study"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27018681",
   "doi": "10.1097/PRS.0000000000002018",
   "title": "Body Image Disorders and Surgical Timing in Patients Affected by Poland Syndrome: Data Analysis of 58 Case Studies",
   "authors": [
    "Baldelli I",
    "Santi P",
    "Dova L",
    "et al."
   ],
   "journal": "Plastic and reconstructive surgery",
   "year": "2016",
   "volume": "137",
   "pages": "1273-1282",
   "pubtypes": [],
   "codes": [
    "2911"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "27530094",
   "doi": "10.1002/ajmg.a.37890",
   "title": "Congenital limb deficiencies with vascular etiology: Possible association with maternal thrombophilia",
   "authors": [
    "Ordal L",
    "Keunen J",
    "Martin N",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2016",
   "volume": "170",
   "pages": "3083-3089",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "26860062",
   "doi": "10.1038/ejhg.2016.7",
   "title": "De novo PIK3R2 variant causes polymicrogyria, corpus callosum hyperplasia and focal cortical dysplasia",
   "authors": [
    "Terrone G",
    "Voisin N",
    "Abdullah Alfaiz A",
    "et al."
   ],
   "journal": "European journal of human genetics : EJHG",
   "year": "2016",
   "volume": "24",
   "pages": "1359-62",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27175919",
   "doi": "10.1371/journal.pone.0155493",
   "title": "Degenerative Changes in the Cervical Spine Are More Common in Middle-Aged Individuals with Thalidomide Embryopathy than in Healthy Controls",
   "authors": [
    "Ghassemi Jahani SA",
    "Danielsson A",
    "Ab-Fawaz R",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2016",
   "volume": "11",
   "pages": "e0155493",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "27666822",
   "doi": "10.1038/srep34232",
   "title": "Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome",
   "authors": [
    "Duran I",
    "Taylor SP",
    "Zhang W",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2016",
   "volume": "6",
   "pages": "34232",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27028286",
   "doi": "10.1111/bcp.12947",
   "title": "EUROmediCAT signal detection: an evaluation of selected congenital anomaly-medication associations",
   "authors": [
    "Given JE",
    "Loane M",
    "Luteijn JM",
    "et al."
   ],
   "journal": "British journal of clinical pharmacology",
   "year": "2016",
   "volume": "82",
   "pages": "1094-109",
   "pubtypes": [
    "Evaluation Study"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "published on the website of Mainz registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Mainz registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ]
  },
  {
   "pmid": "27751757",
   "doi": "10.1016/j.reprotox.2016.10.003",
   "title": "Genomic and in silico analyses of CRBN gene and thalidomide embryopathy in humans",
   "authors": [
    "Vianna FS",
    "Kowalski TW",
    "Tovo-Rodrigues L",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "2016",
   "volume": "66",
   "pages": "99-106",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27854003",
   "doi": "10.1007/s11832-016-0797-6",
   "title": "Health-related quality of life and function in middle-aged individuals with thalidomide embryopathy",
   "authors": [
    "Ghassemi Jahani SA",
    "Karlsson J",
    "Brisby H",
    "et al."
   ],
   "journal": "Journal of children's orthopaedics",
   "year": "2016",
   "volume": "10",
   "pages": "691-703",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27567725",
   "doi": "10.1016/j.crad.2016.07.015",
   "title": "Internal anomalies in thalidomide embryopathy: results of imaging screening by CT and MRI",
   "authors": [
    "Tajima T",
    "Wada T",
    "Yoshizawa A",
    "et al."
   ],
   "journal": "Clinical radiology",
   "year": "2016",
   "volume": "71",
   "pages": "1199.e1-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "26687907",
   "doi": "10.1016/j.rbmo.2015.11.016",
   "title": "Investigation of possible teratogenic effects in the offspring of mice exposed to methylphenidate during pregnancy",
   "authors": [
    "Costa Gde A",
    "Galvão TC",
    "Bacchi AD",
    "et al."
   ],
   "journal": "Reproductive biomedicine online",
   "year": "2016",
   "volume": "32",
   "pages": "170-7",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27865944",
   "doi": "10.1016/j.ejogrb.2016.11.007",
   "title": "Misoprostol exposure during the first trimester of pregnancy: Is the malformation risk varying depending on the indication?",
   "authors": [
    "Auffret M",
    "Bernard-Phalippon N",
    "Dekemp J",
    "et al."
   ],
   "journal": "European journal of obstetrics, gynecology, and reproductive biology",
   "year": "2016",
   "volume": "207",
   "pages": "188-192",
   "pubtypes": [
    "Comparative Study",
    "Multicenter Study",
    "Observational Study"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "26956253",
   "doi": "10.1038/ejhg.2016.14",
   "title": "Mosaic CREBBP mutation causes overlapping clinical features of Rubinstein-Taybi and Filippi syndromes",
   "authors": [
    "de Vries TI",
    "Monroe GR",
    "van Belzen MJ",
    "et al."
   ],
   "journal": "European journal of human genetics : EJHG",
   "year": "2016",
   "volume": "24",
   "pages": "1363-6",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27004986",
   "doi": "10.1038/srep23404",
   "title": "New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors",
   "authors": [
    "Kowalski TW",
    "Fraga LR",
    "Tovo-Rodrigues L",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2016",
   "volume": "6",
   "pages": "23404",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "27100829",
   "doi": "10.1371/journal.pone.0152902",
   "title": "Peripheral Nerve Dysfunction in Middle-Aged Subjects Born with Thalidomide Embryopathy",
   "authors": [
    "Nicotra A",
    "Newman C",
    "Johnson M",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2016",
   "volume": "11",
   "pages": "e0152902",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "27768243",
   "doi": "10.1002/bdrc.21140",
   "title": "Prenatal exposure to environmental factors and congenital limb defects",
   "authors": [
    "Alexander PG",
    "Clark KL",
    "Tuan RS"
   ],
   "journal": "Birth defects research. Part C, Embryo today : reviews",
   "year": "2016",
   "volume": "108",
   "pages": "243-273",
   "pubtypes": [
    "Review"
   ],
   "codes": [],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27348639",
   "doi": "10.1097/PRS.0000000000002256",
   "title": "Proposal of the TBN Classification of Thoracic Anomalies and Treatment Algorithm for Poland Syndrome",
   "authors": [
    "Romanini MV",
    "Torre M",
    "Santi P",
    "et al."
   ],
   "journal": "Plastic and reconstructive surgery",
   "year": "2016",
   "volume": "138",
   "pages": "50-58",
   "pubtypes": [],
   "codes": [
    "2911"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "27687383",
   "doi": "10.1016/j.jclinane.2016.04.035",
   "title": "Real-time measurement of blood pressure with Nexfin in a patient with thalidomide-related phocomelia",
   "authors": [
    "Earle R",
    "Vaghadia H",
    "Shanahan E",
    "et al."
   ],
   "journal": "Journal of clinical anesthesia",
   "year": "2016",
   "volume": "34",
   "pages": "244-6",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2879",
    "3301",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "27909861",
   "doi": "10.1007/s11832-016-0790-0",
   "title": "Surgical reconstruction for fibular hemimelia",
   "authors": [
    "Paley D"
   ],
   "journal": "Journal of children's orthopaedics",
   "year": "2016",
   "volume": "10",
   "pages": "557-583",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "93323"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "cited by Orphanet for Isolated fibular hemimelia (point prevalence, Worldwide)",
    "cited by Orphanet for Isolated fibular hemimelia (prevalence at birth, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "26254946",
   "doi": "10.1016/j.jhsa.2015.06.114",
   "title": "Symbrachydactyly - Diagnosis, Function, and Treatment",
   "authors": [
    "Woodside JC",
    "Light TR"
   ],
   "journal": "The Journal of hand surgery",
   "year": "2016",
   "volume": "41",
   "pages": "135-43; quiz 143",
   "pubtypes": [
    "Review"
   ],
   "codes": [],
   "topics": [
    "review"
   ],
   "notes": [
    "Symbrachydactyly: diagnosis, function, treatment"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "26903378",
   "doi": "10.1038/srep21419",
   "title": "Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model",
   "authors": [
    "Kazuki Y",
    "Akita M",
    "Kobayashi K",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2016",
   "volume": "6",
   "pages": "21419",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "26191240",
   "doi": "",
   "title": "A missense mutation in TMEM67 causes Meckel-Gruber syndrome type 3 (MKS3): a family from China",
   "authors": [
    "Zhang M",
    "Cheng J",
    "Liu A",
    "et al."
   ],
   "journal": "International journal of clinical and experimental pathology",
   "year": "2015",
   "volume": "8",
   "pages": "5379-86",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "26347425",
   "doi": "10.1002/ajmg.a.37355",
   "title": "Congenital anomalies associated with trisomy 18 or trisomy 13: A registry-based study in 16 European countries, 2000-2011",
   "authors": [
    "Springett A",
    "Wellesley D",
    "Greenlees R",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2015",
   "volume": "167A",
   "pages": "3062-9",
   "pubtypes": [
    "Multicenter Study"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ]
  },
  {
   "pmid": "26008671",
   "doi": "",
   "title": "Congenital constriction ring of limbs in subjects with history of maternal substance use",
   "authors": [
    "Malik S",
    "Lal K",
    "Fatima NG",
    "et al."
   ],
   "journal": "Journal of the College of Physicians and Surgeons--Pakistan : JCPSP",
   "year": "2015",
   "volume": "25",
   "pages": "383-5",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "27600068",
   "doi": "10.3390/microarrays5010002",
   "title": "Identification of Critical Region Responsible for Split Hand/Foot Malformation Type 3 (SHFM3) Phenotype through Systematic Review of Literature and Mapping of Breakpoints Using Microarray Data",
   "authors": [
    "Li CF",
    "Angione K",
    "Milunsky JM"
   ],
   "journal": "Microarrays (Basel, Switzerland)",
   "year": "2015",
   "volume": "5",
   "pages": "",
   "pubtypes": [],
   "codes": [
    "2440",
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25693202",
   "doi": "10.1371/journal.pone.0112716",
   "title": "Inhibited Wnt signaling causes age-dependent abnormalities in the bone matrix mineralization in the Apert syndrome FGFR2(S252W/+) mice",
   "authors": [
    "Zhang L",
    "Chen P",
    "Chen L",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2015",
   "volume": "10",
   "pages": "e112716",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25182137",
   "doi": "10.1038/ejhg.2014.174",
   "title": "Meckel-Gruber Syndrome: a population-based study on prevalence, prenatal diagnosis, clinical features, and survival in Europe",
   "authors": [
    "Barisic I",
    "Boban L",
    "Loane M",
    "et al."
   ],
   "journal": "European journal of human genetics : EJHG",
   "year": "2015",
   "volume": "23",
   "pages": "746-52",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ]
  },
  {
   "pmid": "26033770",
   "doi": "10.1002/bdra.23363",
   "title": "Multicenter investigation of lifestyle-related diseases and visceral disorders in thalidomide embryopathy at around 50 years of age",
   "authors": [
    "Shiga T",
    "Shimbo T",
    "Yoshizawa A"
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2015",
   "volume": "103",
   "pages": "787-93",
   "pubtypes": [
    "Multicenter Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "25572679",
   "doi": "10.1245/s10434-014-4328-8",
   "title": "Omentum for Mammary Disorders: A 30-Year Systematic Review",
   "authors": [
    "Claro F Jr",
    "Sarian LO",
    "Pinto-Neto AM"
   ],
   "journal": "Annals of surgical oncology",
   "year": "2015",
   "volume": "22",
   "pages": "2540-50",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Systematic Review"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25828060",
   "doi": "10.1016/j.reprotox.2015.03.007",
   "title": "Pharmacoepidemiology and thalidomide embryopathy surveillance in Brazil",
   "authors": [
    "Sales Luiz Vianna F",
    "de Oliveira MZ",
    "Sanseverino MT",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "2015",
   "volume": "53",
   "pages": "63-7",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "26159096",
   "doi": "10.1159/000433603",
   "title": "Placento-Cranial Adhesions in Amniotic Band Syndrome and the Role of Surgery in Their Management: An Unusual Case Presentation and Systematic Literature Review",
   "authors": [
    "Menekse G",
    "Mert MK",
    "Olmaz B",
    "et al."
   ],
   "journal": "Pediatric neurosurgery",
   "year": "2015",
   "volume": "50",
   "pages": "204-9",
   "pubtypes": [
    "Case Reports",
    "Systematic Review"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24735486",
   "doi": "10.3109/14767058.2014.915935",
   "title": "Prenatal diagnosis of amniotic band syndrome - risk factors and ultrasonic signs",
   "authors": [
    "Barzilay E",
    "Harel Y",
    "Haas J",
    "et al."
   ],
   "journal": "The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians",
   "year": "2015",
   "volume": "28",
   "pages": "281-3",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "26043318",
   "doi": "10.1002/bdra.23376",
   "title": "Thalidomide embryopathy: Follow-up of cases born between 1959 and 2010",
   "authors": [
    "Kowalski TW",
    "Sanseverino MT",
    "Schuler-Faccini L",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2015",
   "volume": "103",
   "pages": "794-803",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "26006729",
   "doi": "10.1016/j.taap.2015.05.009",
   "title": "Thalidomide induced early gene expression perturbations indicative of human embryopathy in mouse embryonic stem cells",
   "authors": [
    "Gao X",
    "Sprando RL",
    "Yourick JJ"
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "2015",
   "volume": "287",
   "pages": "43-51",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "26043938",
   "doi": "10.1002/bdrc.21096",
   "title": "Thalidomide-induced teratogenesis: history and mechanisms",
   "authors": [
    "Vargesson N"
   ],
   "journal": "Birth defects research. Part C, Embryo today : reviews",
   "year": "2015",
   "volume": "105",
   "pages": "140-56",
   "pubtypes": [
    "Historical Article",
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "25721953",
   "doi": "10.1002/bdra.23360",
   "title": "The association between maternal parity and birth defects",
   "authors": [
    "McNeese ML",
    "Selwyn BJ",
    "Duong H",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2015",
   "volume": "103",
   "pages": "144-56",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25626320",
   "doi": "",
   "title": "[Thalidomide teratogenicity and its direct target identification]",
   "authors": [
    "Ito T",
    "Ando H",
    "Handa H"
   ],
   "journal": "Nihon rinsho. Japanese journal of clinical medicine",
   "year": "2015",
   "volume": "73",
   "pages": "143-8",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "1027",
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24855925",
   "doi": "10.1016/j.jpeds.2013.11.022",
   "title": "50 years ago in the Journal of pediatrics: Drug testing in animals for teratogenic effects. Thalidomide in the pregnant rat",
   "authors": [
    "Cuello-Garcia CA"
   ],
   "journal": "The Journal of pediatrics",
   "year": "2014",
   "volume": "164",
   "pages": "1295",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24360810",
   "doi": "10.1016/j.ajhg.2013.11.020",
   "title": "A noncoding expansion in EIF4A3 causes Richieri-Costa-Pereira syndrome, a craniofacial disorder associated with limb defects",
   "authors": [
    "Favaro FP",
    "Alvizi L",
    "Zechi-Ceide RM",
    "et al."
   ],
   "journal": "American journal of human genetics",
   "year": "2014",
   "volume": "94",
   "pages": "120-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24478176",
   "doi": "10.1002/ajmg.a.36367",
   "title": "A novel mutation (g.106737G>T) in zone of polarizing activity regulatory sequence (ZRS) causes variable limb phenotypes in Werner mesomelia",
   "authors": [
    "Girisha KM",
    "Bidchol AM",
    "Kamath PS",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2014",
   "volume": "164A",
   "pages": "898-906",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25332435",
   "doi": "10.1136/jmedgenet-2014-102576",
   "title": "Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I",
   "authors": [
    "Rattanasopha S",
    "Tongkobpetch S",
    "Srichomthong C",
    "et al."
   ],
   "journal": "Journal of medical genetics",
   "year": "2014",
   "volume": "51",
   "pages": "817-23",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24885342",
   "doi": "10.1186/1471-2350-15-63",
   "title": "De novo deletion of chromosome 11q12.3 in monozygotic twins affected by Poland Syndrome",
   "authors": [
    "Vaccari CM",
    "Romanini MV",
    "Musante I",
    "et al."
   ],
   "journal": "BMC medical genetics",
   "year": "2014",
   "volume": "15",
   "pages": "63",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "24344727",
   "doi": "10.1111/cga.12046",
   "title": "Effects of thalidomide on Fgf8, Bmp4 and Hoxa11 expression in the limb bud in Kbl:JW rabbit embryos",
   "authors": [
    "Kawamura Y",
    "Yamashita T",
    "Yamauchi T",
    "et al."
   ],
   "journal": "Congenital anomalies",
   "year": "2014",
   "volume": "54",
   "pages": "54-62",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24670387",
   "doi": "10.1016/j.tox.2014.03.005",
   "title": "Exposure to an environmentally relevant mixture of brominated flame retardants affects fetal development in Sprague-Dawley rats",
   "authors": [
    "Berger RG",
    "Lefèvre PL",
    "Ernest SR",
    "et al."
   ],
   "journal": "Toxicology",
   "year": "2014",
   "volume": "320",
   "pages": "56-66",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25551112",
   "doi": "",
   "title": "Genetic, chromosomal, and syndromic causes of neural tube defects",
   "authors": [
    "Seidahmed MZ",
    "Abdelbasit OB",
    "Shaheed MM",
    "et al."
   ],
   "journal": "Saudi medical journal",
   "year": "2014",
   "volume": "35 Suppl 1",
   "pages": "S49-56",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25131394",
   "doi": "10.1002/bdra.23278",
   "title": "Heterozygous FGF8 mutations in patients presenting cryptorchidism and multiple VATER/VACTERL features without limb anomalies",
   "authors": [
    "Zeidler C",
    "Woelfle J",
    "Draaken M",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2014",
   "volume": "100",
   "pages": "750-9",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ]
  },
  {
   "pmid": "25410508",
   "doi": "10.2106/JBJS.N.00155",
   "title": "High risk for major nonlimb anomalies associated with lower-limb deficiency: a population-based study",
   "authors": [
    "Syvänen J",
    "Nietosvaara Y",
    "Ritvanen A",
    "et al."
   ],
   "journal": "The Journal of bone and joint surgery. American volume",
   "year": "2014",
   "volume": "96",
   "pages": "1898-904",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "Finland, lower limb deficiencies"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "25344219",
   "doi": "10.1186/s13023-014-0156-y",
   "title": "Holt Oram syndrome: a registry-based study in Europe",
   "authors": [
    "Barisic I",
    "Boban L",
    "Greenlees R",
    "et al."
   ],
   "journal": "Orphanet journal of rare diseases",
   "year": "2014",
   "volume": "9",
   "pages": "156",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2879",
    "392",
    "93320"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Holt-Oram syndrome (prevalence at birth, Europe)",
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)",
    "Orphanet"
   ]
  },
  {
   "pmid": "25301261",
   "doi": "10.1007/s11832-014-0609-9",
   "title": "Long-term follow-up of thalidomide embryopathy: malformations and development of osteoarthritis in the lower extremities and evaluation of upper extremity function",
   "authors": [
    "Ghassemi Jahani SA",
    "Danielson B",
    "Karlsson J",
    "et al."
   ],
   "journal": "Journal of children's orthopaedics",
   "year": "2014",
   "volume": "8",
   "pages": "423-33",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "24743779",
   "doi": "10.4161/org.28819",
   "title": "Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant",
   "authors": [
    "Davey MG",
    "McTeir L",
    "Barrie AM",
    "et al."
   ],
   "journal": "Organogenesis",
   "year": "2014",
   "volume": "10",
   "pages": "177-85",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25132072",
   "doi": "10.1002/bdra.23292",
   "title": "Maternal periconceptional alcohol consumption and congenital limb deficiencies",
   "authors": [
    "Caspers Conway KM",
    "Romitti PA",
    "Holmes L",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2014",
   "volume": "100",
   "pages": "863-76",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24907542",
   "doi": "10.1016/j.ijscr.2014.05.002",
   "title": "Measurement of blood pressure in a thalidomide-impaired patient who required ovarian cystectomy: A case report",
   "authors": [
    "Shiga Y",
    "Nojiri F",
    "Yoshizawa A",
    "et al."
   ],
   "journal": "International journal of surgery case reports",
   "year": "2014",
   "volume": "5",
   "pages": "428-30",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "23593966",
   "doi": "10.1111/bcp.12138",
   "title": "Methylphenidate use in pregnancy and lactation: a systematic review of evidence",
   "authors": [
    "Bolea-Alamanac BM",
    "Green A",
    "Verma G",
    "et al."
   ],
   "journal": "British journal of clinical pharmacology",
   "year": "2014",
   "volume": "77",
   "pages": "96-101",
   "pubtypes": [
    "Case Reports",
    "Systematic Review"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24084572",
   "doi": "10.1038/ejhg.2013.210",
   "title": "Mutation of fibulin-1 causes a novel syndrome involving the central nervous system and connective tissues",
   "authors": [
    "Bohlega S",
    "Al-Ajlan H",
    "Al-Saif A"
   ],
   "journal": "European journal of human genetics : EJHG",
   "year": "2014",
   "volume": "22",
   "pages": "640-3",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24548169",
   "doi": "10.1111/pcn.12152",
   "title": "Psychological and mental health problems in patients with thalidomide embryopathy in Japan",
   "authors": [
    "Imai K",
    "Iida T",
    "Yamamoto M",
    "et al."
   ],
   "journal": "Psychiatry and clinical neurosciences",
   "year": "2014",
   "volume": "68",
   "pages": "479-86",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "24087950",
   "doi": "10.3109/14767058.2013.850485",
   "title": "Teratogenic effect of hydroxyethylrutoside, a flavonoid derivate drug--a population-based case-control study",
   "authors": [
    "Pósfai E",
    "Bánhidy F",
    "Czeizel AE"
   ],
   "journal": "The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians",
   "year": "2014",
   "volume": "27",
   "pages": "1093-8",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25053433",
   "doi": "10.1242/dev.105924",
   "title": "The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2",
   "authors": [
    "Chang CF",
    "Schock EN",
    "O'Hare EA",
    "et al."
   ],
   "journal": "Development (Cambridge, England)",
   "year": "2014",
   "volume": "141",
   "pages": "3003-12",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "25181518",
   "doi": "10.1002/bdra.23294",
   "title": "Vascular limb defects and maternal age",
   "authors": [
    "Nasri HZ",
    "Westgate MN",
    "Macklin EA",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2014",
   "volume": "100",
   "pages": "760-3",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23403234",
   "doi": "10.1016/j.gene.2013.01.047",
   "title": "A novel homozygous 10 nucleotide deletion in BBS10 causes Bardet-Biedl syndrome in a Pakistani family",
   "authors": [
    "Agha Z",
    "Iqbal Z",
    "Azam M",
    "et al."
   ],
   "journal": "Gene",
   "year": "2013",
   "volume": "519",
   "pages": "177-81",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23948678",
   "doi": "10.1016/j.bone.2013.07.039",
   "title": "A novel mutation outside homeodomain of HOXD13 causes synpolydactyly in a Chinese family",
   "authors": [
    "Zhou X",
    "Zheng C",
    "He B",
    "et al."
   ],
   "journal": "Bone",
   "year": "2013",
   "volume": "57",
   "pages": "237-41",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24348270",
   "doi": "10.1371/journal.pgen.1003998",
   "title": "A trans-acting protein effect causes severe eye malformation in the Mp mouse",
   "authors": [
    "Rainger J",
    "Keighren M",
    "Keene DR",
    "et al."
   ],
   "journal": "PLoS genetics",
   "year": "2013",
   "volume": "9",
   "pages": "e1003998",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24032294",
   "doi": "",
   "title": "Associated malformations among infants with radial ray deficiency",
   "authors": [
    "Stoll C",
    "Dott B",
    "Alembik Y",
    "et al."
   ],
   "journal": "Genetic counseling (Geneva, Switzerland)",
   "year": "2013",
   "volume": "24",
   "pages": "223-34",
   "pubtypes": [
    "Meta-Analysis"
   ],
   "codes": [
    "392",
    "93321"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24237863",
   "doi": "10.1186/1471-2474-14-323",
   "title": "Birth prevalence for congenital limb defects in the northern Netherlands: a 30-year population-based study",
   "authors": [
    "Vasluian E",
    "van der Sluis CK",
    "van Essen AJ",
    "et al."
   ],
   "journal": "BMC musculoskeletal disorders",
   "year": "2013",
   "volume": "14",
   "pages": "323",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "Northern Netherlands, 30-year birth prevalence of limb defects"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "23322606",
   "doi": "10.1002/ajmg.a.35707",
   "title": "Characteristics and associated anomalies in radial ray deficiencies in Finland--a population-based study",
   "authors": [
    "Pakkasjärvi N",
    "Koskimies E",
    "Ritvanen A",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2013",
   "volume": "161A",
   "pages": "261-7",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "Finland, radial ray deficiencies"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "24080097",
   "doi": "10.1016/j.ecoenv.2013.09.010",
   "title": "Effect of exposure to contaminated pond sediments on survival, development, and enzyme and blood biomarkers in veined treefrog (Trachycephalus typhonius) tadpoles",
   "authors": [
    "Peltzer PM",
    "Lajmanovich RC",
    "Attademo AM",
    "et al."
   ],
   "journal": "Ecotoxicology and environmental safety",
   "year": "2013",
   "volume": "98",
   "pages": "142-51",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23532946",
   "doi": "10.1002/ajmg.a.35839",
   "title": "Fraser syndrome: epidemiological study in a European population",
   "authors": [
    "Barisic I",
    "Odak L",
    "Loane M",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2013",
   "volume": "161A",
   "pages": "1012-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ]
  },
  {
   "pmid": "23419139",
   "doi": "10.1021/tx400008g",
   "title": "In vivo drug interactions of the teratogen thalidomide with midazolam: heterotropic cooperativity of human cytochrome P450 in humanized TK-NOG mice",
   "authors": [
    "Yamazaki H",
    "Suemizu H",
    "Murayama N",
    "et al."
   ],
   "journal": "Chemical research in toxicology",
   "year": "2013",
   "volume": "26",
   "pages": "486-9",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23972535",
   "doi": "10.1016/j.bjps.2013.08.003",
   "title": "Laparoscopically harvested omental flap for breast reconstruction in Poland syndrome",
   "authors": [
    "Romanini MV",
    "Vidal C",
    "Godoy J",
    "et al."
   ],
   "journal": "Journal of plastic, reconstructive & aesthetic surgery : JPRAS",
   "year": "2013",
   "volume": "66",
   "pages": "e303-9",
   "pubtypes": [],
   "codes": [
    "2911"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "23078293",
   "doi": "10.1111/ene.12005",
   "title": "Late-onset neurological symptoms in thalidomide-exposed subjects: a study of an Australasian cohort",
   "authors": [
    "Jankelowitz SK",
    "Spies JM",
    "Burke D"
   ],
   "journal": "European journal of neurology",
   "year": "2013",
   "volume": "20",
   "pages": "509-514",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "24282587",
   "doi": "10.1371/journal.pone.0081369",
   "title": "Maternal age, parity and isolated birth defects: a population-based case-control study in Shenzhen, China",
   "authors": [
    "Luo YL",
    "Cheng YL",
    "Gao XH",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2013",
   "volume": "8",
   "pages": "e81369",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23690510",
   "doi": "10.1542/peds.2012-2941",
   "title": "Maternal mosaicism confounds the neonatal diagnosis of type 1 Timothy syndrome",
   "authors": [
    "Dufendach KA",
    "Giudicessi JR",
    "Boczek NJ",
    "et al."
   ],
   "journal": "Pediatrics",
   "year": "2013",
   "volume": "131",
   "pages": "e1991-5",
   "pubtypes": [
    "Case Reports",
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24134526",
   "doi": "10.1111/ppe.12075",
   "title": "Maternal periconceptional exposure to cigarette smoking and congenital limb deficiencies",
   "authors": [
    "Caspers KM",
    "Romitti PA",
    "Lin S",
    "et al."
   ],
   "journal": "Paediatric and perinatal epidemiology",
   "year": "2013",
   "volume": "27",
   "pages": "509-20",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23826203",
   "doi": "10.1371/journal.pone.0067101",
   "title": "Opinions of youngsters with congenital below-elbow deficiency, and those of their parents and professionals concerning prosthetic use and rehabilitation treatment",
   "authors": [
    "Vasluian E",
    "de Jong IG",
    "Janssen WG",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2013",
   "volume": "8",
   "pages": "e67101",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "living"
   ],
   "notes": [
    "published on the website of Aussiehands (Australia)"
   ],
   "via": [
    "Aussiehands (Australia)"
   ]
  },
  {
   "pmid": "23823863",
   "doi": "10.1024/0301-1526/a000292",
   "title": "Peripheral arterial reconstruction in a patient with thalidomide embryopathy and chronic occlusion of the femoral artery",
   "authors": [
    "Mamopoulos A",
    "Nowak T",
    "Luther B"
   ],
   "journal": "VASA. Zeitschrift fur Gefasskrankheiten",
   "year": "2013",
   "volume": "42",
   "pages": "304-7",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24055736",
   "doi": "10.1016/j.niox.2013.09.002",
   "title": "Polymorphisms in the endothelial nitric oxide synthase gene in thalidomide embryopathy",
   "authors": [
    "Vianna FS",
    "Fraga LR",
    "Tovo-Rodrigues L",
    "et al."
   ],
   "journal": "Nitric oxide : biology and chemistry",
   "year": "2013",
   "volume": "35",
   "pages": "89-92",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "24075380",
   "doi": "10.1016/j.tjog.2013.06.004",
   "title": "Prenatal diagnosis of mosaic trisomy 2 associated with abnormal maternal serum screening, oligohydramnios, intrauterine growth restriction, ventricular septal defect, preaxial polydactyly, and facial dysmorphism",
   "authors": [
    "Chen CP",
    "Chen YY",
    "Chern SR",
    "et al."
   ],
   "journal": "Taiwanese journal of obstetrics & gynecology",
   "year": "2013",
   "volume": "52",
   "pages": "395-400",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23448904",
   "doi": "10.1097/MCD.0b013e32835ffc58",
   "title": "Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy: new cases and review of the main dysmorphological findings",
   "authors": [
    "Vianna FSL",
    "Schüler-Faccini L",
    "Leite JCL",
    "et al."
   ],
   "journal": "Clinical dysmorphology",
   "year": "2013",
   "volume": "22",
   "pages": "59-63",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "",
   "doi": "10.1155/2013/241016",
   "title": "Thalidomide Embryopathy: An Enigmatic Challenge",
   "authors": [
    "Vargesson N"
   ],
   "journal": "ISRN Developmental Biology",
   "year": "2013",
   "volume": "2013",
   "pages": "1-18",
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "23138926",
   "doi": "10.1007/978-1-62703-131-8_36",
   "title": "The thalidomide disaster, lessons from the past",
   "authors": [
    "Ridings JE"
   ],
   "journal": "Methods in molecular biology (Clifton, N.J.)",
   "year": "2013",
   "volume": "947",
   "pages": "575-86",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23710497",
   "doi": "10.1001/jamaophthalmol.2013.1111",
   "title": "Thromboembolism and congenital malformations: from Duane syndrome to thalidomide embryopathy",
   "authors": [
    "Parsa CF",
    "Robert MP"
   ],
   "journal": "JAMA ophthalmology",
   "year": "2013",
   "volume": "131",
   "pages": "439-47",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23917409",
   "doi": "10.1007/s00392-013-0605-y",
   "title": "Treatment of coronary artery disease via MIDCAB in a patient with severe thalidomide phocomelia",
   "authors": [
    "Scherner M",
    "Mihaijlova M",
    "Madershahian N",
    "et al."
   ],
   "journal": "Clinical research in cardiology : official journal of the German Cardiac Society",
   "year": "2013",
   "volume": "102",
   "pages": "857-8",
   "pubtypes": [
    "Case Reports",
    "Letter"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22495965",
   "doi": "10.1002/humu.22097",
   "title": "A novel 13 base pair insertion in the sonic hedgehog ZRS limb enhancer (ZRS/LMBR1) causes preaxial polydactyly with triphalangeal thumb",
   "authors": [
    "Laurell T",
    "Vandermeer JE",
    "Wenger AM",
    "et al."
   ],
   "journal": "Human mutation",
   "year": "2012",
   "volume": "33",
   "pages": "1063-6",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, Non-P.H.S."
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22821755",
   "doi": "10.1002/bdra.23049",
   "title": "Association between maternal age and birth defects of unknown etiology: United States, 1997-2007",
   "authors": [
    "Gill SK",
    "Broussard C",
    "Devine O",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2012",
   "volume": "94",
   "pages": "1010-8",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21960178",
   "doi": "10.1007/s00774-011-0311-7",
   "title": "Bone loss in adult offspring induced by low-dose exposure to teratogens",
   "authors": [
    "Torchinsky A",
    "Mizrahi L",
    "Savion S",
    "et al."
   ],
   "journal": "Journal of bone and mineral metabolism",
   "year": "2012",
   "volume": "30",
   "pages": "270-80",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22252055",
   "doi": "10.1016/j.taap.2012.01.001",
   "title": "Cadmium-induced teratogenicity: association with ROS-mediated endoplasmic reticulum stress in placenta",
   "authors": [
    "Wang Z",
    "Wang H",
    "Xu ZM",
    "et al."
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "2012",
   "volume": "259",
   "pages": "236-47",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22663328",
   "doi": "10.3109/01443615.2012.673037",
   "title": "Carbamazepine use in pregnancy and coincidental thalidomide-like phocomelia in a newborn",
   "authors": [
    "Dursun A",
    "Karadağ N",
    "Karagöl B",
    "et al."
   ],
   "journal": "Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology",
   "year": "2012",
   "volume": "32",
   "pages": "488-9",
   "pubtypes": [
    "Case Reports",
    "Comparative Study"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22348778",
   "doi": "10.1111/j.1741-4520.2011.00351.x",
   "title": "Deciphering the mystery of thalidomide teratogenicity",
   "authors": [
    "Ito T",
    "Handa H"
   ],
   "journal": "Congenital anomalies",
   "year": "2012",
   "volume": "52",
   "pages": "1-7",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [
    "1027",
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22145781",
   "doi": "10.2165/11591270-000000000-00000",
   "title": "Drug exposure and pregnancy outcome in Mozambique",
   "authors": [
    "Sevene E",
    "Bardají A",
    "Mariano A",
    "et al."
   ],
   "journal": "Paediatric drugs",
   "year": "2012",
   "volume": "14",
   "pages": "43-9",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23272276",
   "doi": "",
   "title": "Epidemiology and risk factors of amniotic band syndrome, or ADAM sequence",
   "authors": [
    "Cignini P",
    "Giorlandino C",
    "Padula F",
    "et al."
   ],
   "journal": "Journal of prenatal medicine",
   "year": "2012",
   "volume": "6",
   "pages": "59-63",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22965740",
   "doi": "10.1002/ajmg.a.35565",
   "title": "Evaluation of genes involved in limb development, angiogenesis, and coagulation as risk factors for congenital limb deficiencies",
   "authors": [
    "Browne ML",
    "Carter TC",
    "Kay DM",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2012",
   "volume": "158A",
   "pages": "2463-72",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22892220",
   "doi": "10.1017/S0022215112001429",
   "title": "Facial palsy in individuals with thalidomide embryopathy: frequency and characteristics",
   "authors": [
    "Sjögreen L",
    "Kiliaridis S"
   ],
   "journal": "The Journal of laryngology and otology",
   "year": "2012",
   "volume": "126",
   "pages": "902-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "22955538",
   "doi": "10.1097/BPO.0b013e318269c898",
   "title": "Hand and upper limb anomalies in Poland syndrome: a new proposal of classification",
   "authors": [
    "Catena N",
    "Divizia MT",
    "Calevo MG",
    "et al."
   ],
   "journal": "Journal of pediatric orthopedics",
   "year": "2012",
   "volume": "32",
   "pages": "727-31",
   "pubtypes": [],
   "codes": [
    "2911"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "22371332",
   "doi": "10.1002/bdra.22889",
   "title": "Is maternal parity an independent risk factor for birth defects?",
   "authors": [
    "Duong HT",
    "Hoyt AT",
    "Carmichael SL",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2012",
   "volume": "94",
   "pages": "230-6",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22563320",
   "doi": "10.3389/fphys.2012.00121",
   "title": "Loss-of-Function of Gli3 in Mice Causes Abnormal Frontal Bone Morphology and Premature Synostosis of the Interfrontal Suture",
   "authors": [
    "Veistinen L",
    "Takatalo M",
    "Tanimoto Y",
    "et al."
   ],
   "journal": "Frontiers in physiology",
   "year": "2012",
   "volume": "3",
   "pages": "121",
   "pubtypes": [],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22903936",
   "doi": "10.1002/bdra.23050",
   "title": "Maternal caffeine consumption and risk of congenital limb deficiencies",
   "authors": [
    "Chen L",
    "Bell EM",
    "Browne ML",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2012",
   "volume": "94",
   "pages": "1033-43",
   "pubtypes": [
    "Multicenter Study"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22997553",
   "doi": "10.1038/srep00679",
   "title": "Nitric oxide rescues thalidomide mediated teratogenicity",
   "authors": [
    "Siamwala JH",
    "Veeriah V",
    "Priya MK",
    "et al."
   ],
   "journal": "Scientific reports",
   "year": "2012",
   "volume": "2",
   "pages": "679",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23181494",
   "doi": "10.1111/j.1741-4520.2012.00380.x",
   "title": "Stability of the reproductive variables and fetal malformations from control animals and animals treated with thalidomide in Kbl:JW rabbits over two decades",
   "authors": [
    "Kawamura Y",
    "Matsumoto K",
    "Sato K"
   ],
   "journal": "Congenital anomalies",
   "year": "2012",
   "volume": "52",
   "pages": "191-202",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22434686",
   "doi": "10.1002/bdra.23003",
   "title": "Teratogen update: methotrexate",
   "authors": [
    "Hyoun SC",
    "Običan SG",
    "Scialli AR"
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2012",
   "volume": "94",
   "pages": "187-207",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2440",
    "2879",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "23493485",
   "doi": "",
   "title": "Teratogenic effects of sulfur mustard on mice fetuses",
   "authors": [
    "Sanjarmoosavi N",
    "Sanjarmoosavi N",
    "Shahsavan M",
    "et al."
   ],
   "journal": "Iranian journal of basic medical sciences",
   "year": "2012",
   "volume": "15",
   "pages": "853-9",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22650376",
   "doi": "10.2174/156802612801784407",
   "title": "Thalidomide: chemistry, therapeutic potential and oxidative stress induced teratogenicity",
   "authors": [
    "Kumar N",
    "Sharma U",
    "Singh C",
    "et al."
   ],
   "journal": "Current topics in medicinal chemistry",
   "year": "2012",
   "volume": "12",
   "pages": "1436-55",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19890655",
   "doi": "10.1007/s00404-009-1275-x",
   "title": "\"At fingers' ends\": risk factors and perinatal outcome of pregnancies complicated by digital malformations",
   "authors": [
    "Tzur T",
    "Sheiner E",
    "Weintraub AY",
    "et al."
   ],
   "journal": "Archives of gynecology and obstetrics",
   "year": "2011",
   "volume": "283",
   "pages": "47-52",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21320477",
   "doi": "10.1016/j.cca.2011.02.007",
   "title": "A novel frame-shift mutation of GLI3 causes non-syndromic and complex digital anomalies in a Chinese family",
   "authors": [
    "Cheng F",
    "Ke X",
    "Lv M",
    "et al."
   ],
   "journal": "Clinica chimica acta; international journal of clinical chemistry",
   "year": "2011",
   "volume": "412",
   "pages": "1012-7",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21344627",
   "doi": "10.1002/ajmg.a.33717",
   "title": "A novel homozygous missense mutation (c.610G>A, p.Gly204Ser) in the WNT7A gene causes tetra-amelia in two Saudi families",
   "authors": [
    "Eyaid W",
    "Al-Qattan MM",
    "Al Abdulkareem I",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2011",
   "volume": "155A",
   "pages": "599-604",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "1027",
    "2879",
    "3301"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22002956",
   "doi": "10.1002/ajmg.c.30319",
   "title": "Amelia: a multi-center descriptive epidemiologic study in a large dataset from the International Clearinghouse for Birth Defects Surveillance and Research, and overview of the literature",
   "authors": [
    "Bermejo-Sánchez E",
    "Cuevas L",
    "Amar E",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part C, Seminars in medical genetics",
   "year": "2011",
   "volume": "157C",
   "pages": "288-304",
   "pubtypes": [
    "Multicenter Study",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S.",
    "Review"
   ],
   "codes": [
    "1027",
    "295000"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "Amelia: ICBDSR multi-centre study",
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)",
    "DysNet"
   ]
  },
  {
   "pmid": "20958261",
   "doi": "10.2174/1874467211104010026",
   "title": "Apoptosis induction by thalidomide: critical for limb teratogenicity but therapeutic potential in idiopathic pulmonary fibrosis?",
   "authors": [
    "Knobloch J",
    "Jungck D",
    "Koch A"
   ],
   "journal": "Current molecular pharmacology",
   "year": "2011",
   "volume": "4",
   "pages": "26-61",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21712302",
   "doi": "10.1177/1753193411412869",
   "title": "Children with surgically corrected hand deformities and upper limb deficiencies: self-concept and psychological well-being",
   "authors": [
    "Andersson GB",
    "Gillberg C",
    "Fernell E",
    "et al."
   ],
   "journal": "The Journal of hand surgery, European volume",
   "year": "2011",
   "volume": "36",
   "pages": "795-801",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "living"
   ],
   "notes": [
    "published on the website of Aussiehands (Australia)"
   ],
   "via": [
    "Aussiehands (Australia)"
   ]
  },
  {
   "pmid": "21601997",
   "doi": "10.1016/j.jhsa.2011.03.015",
   "title": "Congenital upper limb deficiencies and associated malformations in Finland: a population-based study",
   "authors": [
    "Koskimies E",
    "Lindfors N",
    "Gissler M",
    "et al."
   ],
   "journal": "The Journal of hand surgery",
   "year": "2011",
   "volume": "36",
   "pages": "1058-65",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "Finland, upper limb deficiencies"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "21045211",
   "doi": "10.1242/dmm.006262",
   "title": "Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome",
   "authors": [
    "Cui C",
    "Chatterjee B",
    "Francis D",
    "et al."
   ],
   "journal": "Disease models & mechanisms",
   "year": "2011",
   "volume": "4",
   "pages": "43-56",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21763481",
   "doi": "10.1016/j.ajhg.2011.06.003",
   "title": "Disruption of a ciliary B9 protein complex causes Meckel syndrome",
   "authors": [
    "Dowdle WE",
    "Robinson JF",
    "Kneist A",
    "et al."
   ],
   "journal": "American journal of human genetics",
   "year": "2011",
   "volume": "89",
   "pages": "94-110",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21502285",
   "doi": "10.1096/fj.10-178814",
   "title": "Embryopathic effects of thalidomide and its hydrolysis products in rabbit embryo culture: evidence for a prostaglandin H synthase (PHS)-dependent, reactive oxygen species (ROS)-mediated mechanism",
   "authors": [
    "Lee CJ",
    "Gonçalves LL",
    "Wells PG"
   ],
   "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
   "year": "2011",
   "volume": "25",
   "pages": "2468-83",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21754997",
   "doi": "10.1371/journal.pone.0021735",
   "title": "Epidemiological surveillance of birth defects compatible with thalidomide embryopathy in Brazil",
   "authors": [
    "Vianna FS",
    "Lopez-Camelo JS",
    "Leite JC",
    "et al."
   ],
   "journal": "PloS one",
   "year": "2011",
   "volume": "6",
   "pages": "e21735",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21814340",
   "doi": "10.4103/0971-6866.82189",
   "title": "Familial clustering of a rare syndrome",
   "authors": [
    "Nadkarni J",
    "Ganesh H",
    "Dwivedi R"
   ],
   "journal": "Indian journal of human genetics",
   "year": "2011",
   "volume": "17",
   "pages": "26-8",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22180729",
   "doi": "10.1371/journal.pbio.1001219",
   "title": "Hyperactive neuroendocrine secretion causes size, feeding, and metabolic defects of C. elegans Bardet-Biedl syndrome mutants",
   "authors": [
    "Lee BH",
    "Liu J",
    "Wong D",
    "et al."
   ],
   "journal": "PLoS biology",
   "year": "2011",
   "volume": "9",
   "pages": "e1001219",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21056704",
   "doi": "10.1016/j.ejmg.2010.10.012",
   "title": "Interstitial deletion of 7q31.32 → q33 secondary to a paracentric inversion of a maternal chromosome 7",
   "authors": [
    "Paskulin GA",
    "Riegel M",
    "Machado Rosa RF",
    "et al."
   ],
   "journal": "European journal of medical genetics",
   "year": "2011",
   "volume": "54",
   "pages": "181-5",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21121869",
   "doi": "10.1517/14740338.2011.527331",
   "title": "Managing the teratogenic risk of thalidomide and lenalidomide: an industry perspective",
   "authors": [
    "Bwire R",
    "Freeman J",
    "Houn F"
   ],
   "journal": "Expert opinion on drug safety",
   "year": "2011",
   "volume": "10",
   "pages": "3-8",
   "pubtypes": [
    "Editorial",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21649676",
   "doi": "10.1111/j.1365-3016.2011.01198.x",
   "title": "Maternal dietary glycaemic intake during pregnancy and the risk of birth defects",
   "authors": [
    "Yazdy MM",
    "Mitchell AA",
    "Liu S",
    "et al."
   ],
   "journal": "Paediatric and perinatal epidemiology",
   "year": "2011",
   "volume": "25",
   "pages": "340-6",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21671374",
   "doi": "10.1002/ajmg.a.34037",
   "title": "Methotrexate and misoprostol teratogenicity: further expansion of the clinical manifestations",
   "authors": [
    "Kozma C",
    "Ramasethu J"
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2011",
   "volume": "155A",
   "pages": "1723-8",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20229166",
   "doi": "10.1007/s10661-010-1395-6",
   "title": "Morphological abnormalities in frogs from a rice-growing region in NSW, Australia, with investigations into pesticide exposure",
   "authors": [
    "Spolyarich N",
    "Hyne RV",
    "Wilson SP",
    "et al."
   ],
   "journal": "Environmental monitoring and assessment",
   "year": "2011",
   "volume": "173",
   "pages": "397-407",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "22002800",
   "doi": "10.1002/ajmg.c.30320",
   "title": "Phocomelia: a worldwide descriptive epidemiologic study in a large series of cases from the International Clearinghouse for Birth Defects Surveillance and Research, and overview of the literature",
   "authors": [
    "Bermejo-Sánchez E",
    "Cuevas L",
    "Amar E",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part C, Seminars in medical genetics",
   "year": "2011",
   "volume": "157C",
   "pages": "305-20",
   "pubtypes": [
    "Multicenter Study",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S.",
    "Review"
   ],
   "codes": [
    "1027",
    "2879"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "published on the website of Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ],
   "via": [
    "Centre Saxony-Anhalt registry of congenital anomalies - contributes to the EUROCAT network (Germany)"
   ]
  },
  {
   "pmid": "21505090",
   "doi": "10.1093/toxsci/kfr084",
   "title": "Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture",
   "authors": [
    "Lee CJ",
    "Gonçalves LL",
    "Wells PG"
   ],
   "journal": "Toxicological sciences : an official journal of the Society of Toxicology",
   "year": "2011",
   "volume": "122",
   "pages": "146-56",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21104612",
   "doi": "10.1055/s-0030-1268855",
   "title": "Risk factors and therapeutic strategy after failure of free flap coverage for lower-limb defects",
   "authors": [
    "Perrot P",
    "Bouffaut AL",
    "Perret C",
    "et al."
   ],
   "journal": "Journal of reconstructive microsurgery",
   "year": "2011",
   "volume": "27",
   "pages": "157-62",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21207098",
   "doi": "10.1007/s00018-010-0619-9",
   "title": "Teratogenic effects of thalidomide: molecular mechanisms",
   "authors": [
    "Ito T",
    "Ando H",
    "Handa H"
   ],
   "journal": "Cellular and molecular life sciences : CMLS",
   "year": "2011",
   "volume": "68",
   "pages": "1569-79",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21507989",
   "doi": "10.1093/toxsci/kfr088",
   "title": "Thalidomide: the tragedy of birth defects and the effective treatment of disease",
   "authors": [
    "Kim JH",
    "Scialli AR"
   ],
   "journal": "Toxicological sciences : an official journal of the Society of Toxicology",
   "year": "2011",
   "volume": "122",
   "pages": "1-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21465618",
   "doi": "10.1002/dvdy.22623",
   "title": "The chicken polydactyly (Po) locus causes allelic imbalance and ectopic expression of Shh during limb development",
   "authors": [
    "Dunn IC",
    "Paton IR",
    "Clelland AK",
    "et al."
   ],
   "journal": "Developmental dynamics : an official publication of the American Association of Anatomists",
   "year": "2011",
   "volume": "240",
   "pages": "1163-72",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "21404644",
   "doi": "",
   "title": "[Molecular mechanism of thalidomide teratogenicity]",
   "authors": [
    "Ito T",
    "Handa H"
   ],
   "journal": "Seikagaku. The Journal of Japanese Biochemical Society",
   "year": "2011",
   "volume": "83",
   "pages": "118-22",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19847792",
   "doi": "10.1002/humu.21142",
   "title": "A specific mutation in the distant sonic hedgehog (SHH) cis-regulator (ZRS) causes Werner mesomelic syndrome (WMS) while complete ZRS duplications underlie Haas type polysyndactyly and preaxial polydactyly (PPD) with or without triphalangeal thumb",
   "authors": [
    "Wieczorek D",
    "Pawlik B",
    "Li Y",
    "et al."
   ],
   "journal": "Human mutation",
   "year": "2010",
   "volume": "31",
   "pages": "81-9",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "93322"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19909992",
   "doi": "10.1016/j.jtcvs.2009.08.024",
   "title": "Dextrocardia in patients with Poland syndrome: phenotypic characterization provides insight into the pathogenesis",
   "authors": [
    "Torre M",
    "Baban A",
    "Buluggiu A",
    "et al."
   ],
   "journal": "The Journal of thoracic and cardiovascular surgery",
   "year": "2010",
   "volume": "139",
   "pages": "1177-82",
   "pubtypes": [
    "Multicenter Study"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "20104599",
   "doi": "10.1002/ajmg.c.30233",
   "title": "Epidemiology of holoprosencephaly: Prevalence and risk factors",
   "authors": [
    "Orioli IM",
    "Castilla EE"
   ],
   "journal": "American journal of medical genetics. Part C, Seminars in medical genetics",
   "year": "2010",
   "volume": "154C",
   "pages": "13-21",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19751816",
   "doi": "10.1016/j.reprotox.2009.09.003",
   "title": "Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide",
   "authors": [
    "Ema M",
    "Ise R",
    "Kato H",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "2010",
   "volume": "29",
   "pages": "49-56",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "1027",
    "2913",
    "93458",
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20223979",
   "doi": "10.1126/science.1177319",
   "title": "Identification of a primary target of thalidomide teratogenicity",
   "authors": [
    "Ito T",
    "Ando H",
    "Suzuki T",
    "et al."
   ],
   "journal": "Science (New York, N.Y.)",
   "year": "2010",
   "volume": "327",
   "pages": "1345-50",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20498623",
   "doi": "10.1097/BPB.0b013e32832d5d7d",
   "title": "Limb length discrepancy and congenital limb anomalies in fibular hemimelia",
   "authors": [
    "Rodriguez-Ramirez A",
    "Thacker MM",
    "Becerra LC",
    "et al."
   ],
   "journal": "Journal of pediatric orthopedics. Part B",
   "year": "2010",
   "volume": "19",
   "pages": "436-40",
   "pubtypes": [],
   "codes": [
    "93323"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Isolated fibular hemimelia (point prevalence, Worldwide)",
    "cited by Orphanet for Isolated fibular hemimelia (prevalence at birth, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "20431566",
   "doi": "10.1038/nrd3164",
   "title": "Target identification: unravelling thalidomide teratogenicity",
   "authors": [
    "Flemming A"
   ],
   "journal": "Nature reviews. Drug discovery",
   "year": "2010",
   "volume": "9",
   "pages": "361",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20943929",
   "doi": "10.1523/JNEUROSCI.3650-10.2010",
   "title": "The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence",
   "authors": [
    "Magnani D",
    "Hasenpusch-Theil K",
    "Jacobs EC",
    "et al."
   ],
   "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience",
   "year": "2010",
   "volume": "30",
   "pages": "13883-94",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20558369",
   "doi": "10.1056/NEJMoa0907328",
   "title": "Valproic acid monotherapy in pregnancy and major congenital malformations",
   "authors": [
    "Jentink J",
    "Loane MA",
    "Dolk H",
    "et al."
   ],
   "journal": "The New England journal of medicine",
   "year": "2010",
   "volume": "362",
   "pages": "2185-93",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "published on the website of EUROCAT (EU RD Platform, JRC) (Italy)"
   ],
   "via": [
    "EUROCAT (EU RD Platform, JRC) (Italy)"
   ]
  },
  {
   "pmid": "20506663",
   "doi": "",
   "title": "[Prevalence of congenital split hand/split foot malformation in Chinese population]",
   "authors": [
    "Dai L",
    "Li YH",
    "Deng Y",
    "et al."
   ],
   "journal": "Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition",
   "year": "2010",
   "volume": "41",
   "pages": "320-3",
   "pubtypes": [
    "English Abstract",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Isolated split hand-split foot malformation (prevalence at birth, Canada)",
    "cited by Orphanet for Isolated split hand-split foot malformation (prevalence at birth, China)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "19291772",
   "doi": "10.1002/ajmg.a.32740",
   "title": "A ZRS duplication causes syndactyly type IV with tibial hypoplasia",
   "authors": [
    "Wu L",
    "Liang D",
    "Niikawa N",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2009",
   "volume": "149A",
   "pages": "816-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93322",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19461659",
   "doi": "10.1038/jhg.2009.48",
   "title": "A novel single-base deletion in ROR2 causes atypical brachydactyly type B1 with cutaneous syndactyly in a large Chinese family",
   "authors": [
    "Lv D",
    "Luo Y",
    "Yang W",
    "et al."
   ],
   "journal": "Journal of human genetics",
   "year": "2009",
   "volume": "54",
   "pages": "422-5",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20072863",
   "doi": "10.1007/s12098-009-0273-0",
   "title": "A rare association of congenital absence of femur and fibular hemimelia with maternal hyperpyrexia",
   "authors": [
    "Kumar D",
    "Krishnamurthy S"
   ],
   "journal": "Indian journal of pediatrics",
   "year": "2009",
   "volume": "76",
   "pages": "1178-9",
   "pubtypes": [
    "Case Reports",
    "Letter"
   ],
   "codes": [
    "93323"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18572003",
   "doi": "10.1016/j.bjps.2008.01.031",
   "title": "Further support for the vascular aetiology of Poland syndrome--a case report",
   "authors": [
    "Dustagheer S",
    "Basheer MH",
    "Collins A",
    "et al."
   ],
   "journal": "Journal of plastic, reconstructive & aesthetic surgery : JPRAS",
   "year": "2009",
   "volume": "62",
   "pages": "e360-1",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19672683",
   "doi": "10.1007/s10577-009-9059-5",
   "title": "Implication of long-distance regulation of the HOXA cluster in a patient with postaxial polydactyly",
   "authors": [
    "Lodder EM",
    "Eussen BH",
    "van Hassel DA",
    "et al."
   ],
   "journal": "Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology",
   "year": "2009",
   "volume": "17",
   "pages": "737-44",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19591116",
   "doi": "10.1002/bdra.20600",
   "title": "Maternal caffeine intake during pregnancy and orofacial clefts",
   "authors": [
    "Collier SA",
    "Browne ML",
    "Rasmussen SA",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2009",
   "volume": "85",
   "pages": "842-9",
   "pubtypes": [
    "Research Support, U.S. Gov't, Non-P.H.S.",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19350655",
   "doi": "10.1002/bdra.20587",
   "title": "Maternal nutrient intake and risks for transverse and longitudinal limb deficiencies: data from the National Birth Defects Prevention Study, 1997-2003",
   "authors": [
    "Robitaille J",
    "Carmichael SL",
    "Shaw GM",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2009",
   "volume": "85",
   "pages": "773-9",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19067400",
   "doi": "10.1002/bdra.20524",
   "title": "Maternal vasoactive exposures, amniotic bands, and terminal transverse limb defects",
   "authors": [
    "Werler MM",
    "Bosco JL",
    "Shapira SK",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2009",
   "volume": "85",
   "pages": "52-7",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19274763",
   "doi": "10.1002/bdra.20577",
   "title": "Microarray analysis of murine limb bud ectoderm and mesoderm after exposure to cadmium or acetazolamide",
   "authors": [
    "Schreiner CM",
    "Bell SM",
    "Scott WJ Jr"
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2009",
   "volume": "85",
   "pages": "588-98",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19533787",
   "doi": "10.1002/ajmg.a.32922",
   "title": "Poland syndrome with bilateral features: case description with review of the literature",
   "authors": [
    "Baban A",
    "Torre M",
    "Bianca S",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2009",
   "volume": "149A",
   "pages": "1597-602",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "1570",
    "2911"
   ],
   "topics": [
    "review"
   ],
   "notes": [
    "published on the website of AISP – Sindrome di Poland (Italy)"
   ],
   "via": [
    "AISP – Sindrome di Poland (Italy)"
   ]
  },
  {
   "pmid": "19433787",
   "doi": "10.1073/pnas.0901505106",
   "title": "Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation",
   "authors": [
    "Therapontos C",
    "Erskine L",
    "Gardner ER",
    "et al."
   ],
   "journal": "Proceedings of the National Academy of Sciences of the United States of America",
   "year": "2009",
   "volume": "106",
   "pages": "8573-8",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, N.I.H., Intramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19921660",
   "doi": "10.1002/bies.200900103",
   "title": "Thalidomide-induced limb defects: resolving a 50-year-old puzzle",
   "authors": [
    "Vargesson N"
   ],
   "journal": "BioEssays : news and reviews in molecular, cellular and developmental biology",
   "year": "2009",
   "volume": "31",
   "pages": "1327-36",
   "pubtypes": [
    "Historical Article",
    "Review"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19183988",
   "doi": "10.1007/s00256-008-0638-x",
   "title": "The carpal bones in Poland syndrome",
   "authors": [
    "Friedman T",
    "Reed M",
    "Elliott AM"
   ],
   "journal": "Skeletal radiology",
   "year": "2009",
   "volume": "38",
   "pages": "585-91",
   "pubtypes": [
    "Meta-Analysis"
   ],
   "codes": [
    "2911",
    "93458"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20193224",
   "doi": "",
   "title": "[A case-control study on genetic and environmental factors regarding polydactyly and syndactyly]",
   "authors": [
    "Luo JY",
    "Fu CH",
    "Yao KB",
    "et al."
   ],
   "journal": "Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi",
   "year": "2009",
   "volume": "30",
   "pages": "903-6",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19497840",
   "doi": "10.1556/OH.2009.28641",
   "title": "[Thalidomide (Contergan) induced limb deficiency in Hungary?]",
   "authors": [
    "Gidai J",
    "Bács E",
    "Czeizel E"
   ],
   "journal": "Orvosi hetilap",
   "year": "2009",
   "volume": "150",
   "pages": "1179-81",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "1027",
    "2879",
    "93320",
    "93323",
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18242159",
   "doi": "10.1016/j.bone.2007.11.019",
   "title": "A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis",
   "authors": [
    "Yin L",
    "Du X",
    "Li C",
    "et al."
   ],
   "journal": "Bone",
   "year": "2008",
   "volume": "42",
   "pages": "631-43",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19072561",
   "doi": "10.1089/gte.2008.0036",
   "title": "A known SOST gene mutation causes sclerosteosis in a familial and an isolated case from Brazilian origin",
   "authors": [
    "Kim CA",
    "Honjo R",
    "Bertola D",
    "et al."
   ],
   "journal": "Genetic testing",
   "year": "2008",
   "volume": "12",
   "pages": "475-9",
   "pubtypes": [
    "Case Reports",
    "Letter"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18554391",
   "doi": "10.1186/1750-1172-3-15",
   "title": "Brachydactyly",
   "authors": [
    "Temtamy SA",
    "Aglan MS"
   ],
   "journal": "Orphanet journal of rare diseases",
   "year": "2008",
   "volume": "3",
   "pages": "15",
   "pubtypes": [
    "Review"
   ],
   "codes": [],
   "topics": [
    "review"
   ],
   "notes": [
    "Brachydactyly review (Orphanet J Rare Dis)"
   ],
   "via": [
    "DysNet"
   ]
  },
  {
   "pmid": "18845601",
   "doi": "10.1136/bmj.a2024",
   "title": "Campaigners demand equal treatment for all thalidomide victims",
   "authors": [
    "Jara M"
   ],
   "journal": "BMJ (Clinical research ed.)",
   "year": "2008",
   "volume": "337",
   "pages": "a2024",
   "pubtypes": [
    "News"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18720052",
   "doi": "10.1080/00016350802307638",
   "title": "Dental status and oral function in an adult group of subjects with thalidomide embryopathy - a clinical and questionnaire study",
   "authors": [
    "Ekfeldt A",
    "Carlsson GE"
   ],
   "journal": "Acta odontologica Scandinavica",
   "year": "2008",
   "volume": "66",
   "pages": "300-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "18383510",
   "doi": "10.1002/bdra.20449",
   "title": "Descriptive epidemiologic features shared by birth defects thought to be related to vascular disruption in Texas, 1996-2002",
   "authors": [
    "Husain T",
    "Langlois PH",
    "Sever LE",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2008",
   "volume": "82",
   "pages": "435-40",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18386809",
   "doi": "10.1002/ajmg.a.32178",
   "title": "Disruption of chromodomain helicase DNA binding protein 2 (CHD2) causes scoliosis",
   "authors": [
    "Kulkarni S",
    "Nagarajan P",
    "Wall J",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2008",
   "volume": "146A",
   "pages": "1117-27",
   "pubtypes": [
    "Case Reports",
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18178536",
   "doi": "10.1016/j.ejmg.2007.08.004",
   "title": "Holoprosencephaly-Polydactyly syndrome: in search of an etiology",
   "authors": [
    "Cordero DR",
    "Bendavid C",
    "Shanske AL",
    "et al."
   ],
   "journal": "European journal of medical genetics",
   "year": "2008",
   "volume": "51",
   "pages": "106-12",
   "pubtypes": [
    "Case Reports",
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18302266",
   "doi": "10.1002/bdra.20444",
   "title": "Proteomic analysis to characterize differential mouse strain sensitivity to cadmium-induced forelimb teratogenesis",
   "authors": [
    "Chen H",
    "Boontheung P",
    "Loo RR",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2008",
   "volume": "82",
   "pages": "187-99",
   "pubtypes": [
    "Comparative Study",
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18418038",
   "doi": "10.4161/cc.7.9.5793",
   "title": "Shedding light on an old mystery: thalidomide suppresses survival pathways to induce limb defects",
   "authors": [
    "Knobloch J",
    "Rüther U"
   ],
   "journal": "Cell cycle (Georgetown, Tex.)",
   "year": "2008",
   "volume": "7",
   "pages": "1121-7",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18400576",
   "doi": "10.1016/S1028-4559(08)60048-0",
   "title": "Syndromes, disorders and maternal risk factors associated with neural tube defects (I)",
   "authors": [
    "Chen CP"
   ],
   "journal": "Taiwanese journal of obstetrics & gynecology",
   "year": "2008",
   "volume": "47",
   "pages": "1-9",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18603496",
   "doi": "10.1016/S1028-4559(08)60070-4",
   "title": "Syndromes, disorders and maternal risk factors associated with neural tube defects (III)",
   "authors": [
    "Chen CP"
   ],
   "journal": "Taiwanese journal of obstetrics & gynecology",
   "year": "2008",
   "volume": "47",
   "pages": "131-40",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18935989",
   "doi": "10.1016/S1028-4559(08)60124-2",
   "title": "Syndromes, disorders and maternal risk factors associated with neural tube defects (VII)",
   "authors": [
    "Chen CP"
   ],
   "journal": "Taiwanese journal of obstetrics & gynecology",
   "year": "2008",
   "volume": "47",
   "pages": "276-82",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18178729",
   "doi": "10.1128/MCB.00553-07",
   "title": "Thalidomide induces limb anomalies by PTEN stabilization, Akt suppression, and stimulation of caspase-dependent cell death",
   "authors": [
    "Knobloch J",
    "Schmitz I",
    "Götz K",
    "et al."
   ],
   "journal": "Molecular and cellular biology",
   "year": "2008",
   "volume": "28",
   "pages": "529-38",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "17003559",
   "doi": "10.1159/000095844",
   "title": "Amniotic band syndrome with limb amputation after exposure to mifepristone in early pregnancy",
   "authors": [
    "Sentilhes L",
    "Patrier S",
    "Chouchene S",
    "et al."
   ],
   "journal": "Fetal diagnosis and therapy",
   "year": "2007",
   "volume": "22",
   "pages": "51-4",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "17159513",
   "doi": "10.1097/MCD.0b013e328010b81c",
   "title": "Aplasia cutis congenita, terminal limb defects and falciform retinal folds: confirmation of a distinct syndrome of vascular disruption",
   "authors": [
    "Prothero J",
    "Nicholl R",
    "Wilson J",
    "et al."
   ],
   "journal": "Clinical dysmorphology",
   "year": "2007",
   "volume": "16",
   "pages": "39-41",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "974"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "17555519",
   "doi": "10.1111/j.1440-169X.2007.00939.x",
   "title": "Clinical features and teratogenic mechanisms of congenital absence of digits",
   "authors": [
    "Ogino T"
   ],
   "journal": "Development, growth & differentiation",
   "year": "2007",
   "volume": "49",
   "pages": "523-31",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "1570",
    "2440",
    "2913",
    "295000",
    "93321",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18000913",
   "doi": "10.1002/ajmg.a.32071",
   "title": "Infrequently studied congenital anomalies as clues to the diagnosis of maternal diabetes mellitus",
   "authors": [
    "Frías JL",
    "Frías JP",
    "Frías PA",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2007",
   "volume": "143A",
   "pages": "2904-9",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "17365642",
   "doi": "10.1080/14639230601097523",
   "title": "Integrating health information: a case study of a health information service for thalidomide survivors",
   "authors": [
    "Johnson M"
   ],
   "journal": "Medical informatics and the Internet in medicine",
   "year": "2007",
   "volume": "32",
   "pages": "27-33",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "17676592",
   "doi": "10.1002/bdra.20384",
   "title": "New cases of thalidomide embryopathy in Brazil",
   "authors": [
    "Schuler-Faccini L",
    "Soares RC",
    "de Sousa AC",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2007",
   "volume": "79",
   "pages": "671-2",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy",
    "published on the website of Stichting NESOS (Netherlands)"
   ],
   "via": [
    "PubMed search",
    "Stichting NESOS (Netherlands)"
   ]
  },
  {
   "pmid": "17676605",
   "doi": "10.1002/bdra.20385",
   "title": "Perturbation of retinoic acid (RA)-mediated limb development suggests a role for diminished RA signaling in the teratogenesis of ethanol",
   "authors": [
    "Johnson CS",
    "Zucker RM",
    "Hunter ES 3rd",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2007",
   "volume": "79",
   "pages": "631-41",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "17956633",
   "doi": "10.1186/1748-7161-2-15",
   "title": "Rare causes of scoliosis and spine deformity: experience and particular features",
   "authors": [
    "Soultanis KC",
    "Payatakes AH",
    "Chouliaras VT",
    "et al."
   ],
   "journal": "Scoliosis",
   "year": "2007",
   "volume": "2",
   "pages": "15",
   "pubtypes": [
    "Case Reports",
    "Retracted Publication"
   ],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "living"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "17283219",
   "doi": "10.1096/fj.06-7603com",
   "title": "Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway",
   "authors": [
    "Knobloch J",
    "Shaughnessy JD Jr",
    "Rüther U"
   ],
   "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
   "year": "2007",
   "volume": "21",
   "pages": "1410-21",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16404586",
   "doi": "10.1007/s00439-005-0129-2",
   "title": "A novel heterozygous deletion in the EVC2 gene causes Weyers acrofacial dysostosis",
   "authors": [
    "Ye X",
    "Song G",
    "Fan M",
    "et al."
   ],
   "journal": "Human genetics",
   "year": "2006",
   "volume": "119",
   "pages": "199-205",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15980115",
   "doi": "10.1136/jmg.2005.033555",
   "title": "Breakpoints around the HOXD cluster result in various limb malformations",
   "authors": [
    "Dlugaszewska B",
    "Silahtaroglu A",
    "Menzel C",
    "et al."
   ],
   "journal": "Journal of medical genetics",
   "year": "2006",
   "volume": "43",
   "pages": "111-8",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16530898",
   "doi": "10.1016/j.jhsb.2006.01.001",
   "title": "Carpal tunnel syndrome accompanying radial dysplasia due to thalidomide embryopathy",
   "authors": [
    "Oshima Y",
    "Okutsu I",
    "Hamanaka I",
    "et al."
   ],
   "journal": "Journal of hand surgery (Edinburgh, Scotland)",
   "year": "2006",
   "volume": "31",
   "pages": "342-4",
   "pubtypes": [],
   "codes": [
    "93321",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19554231",
   "doi": "10.1177/229255030601400104",
   "title": "Constriction band syndrome occurring in the setting of in vitro fertilization and advanced maternal age",
   "authors": [
    "Rinker B",
    "Vasconez HC"
   ],
   "journal": "The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique",
   "year": "2006",
   "volume": "14",
   "pages": "41-4",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16463421",
   "doi": "10.1002/bdra.20232",
   "title": "Differential teratogenesis of all-trans-retinoic acid administered on gestational day 9.5 to SWV and C57BL/6N mice: emphasis on limb dysmorphology",
   "authors": [
    "Collins MD",
    "Eckhoff C",
    "Weiss R",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2006",
   "volume": "76",
   "pages": "96-106",
   "pubtypes": [
    "Comparative Study",
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16955493",
   "doi": "10.1002/bdra.20284",
   "title": "Exposure to 5-bromo-2'-deoxyuridine induces oxidative stress and activator protein-1 DNA binding activity in the embryo",
   "authors": [
    "Sahambi SK",
    "Hales BF"
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2006",
   "volume": "76",
   "pages": "580-91",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16308330",
   "doi": "10.1242/dev.02172",
   "title": "Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function",
   "authors": [
    "Lu P",
    "Minowada G",
    "Martin GR"
   ],
   "journal": "Development (Cambridge, England)",
   "year": "2006",
   "volume": "133",
   "pages": "33-42",
   "pubtypes": [
    "Comparative Study",
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16404282",
   "doi": "10.1097/01.prs.0000194904.81981.71",
   "title": "Maternal cigarette smoking during pregnancy increases the risk of having a child with a congenital digital anomaly",
   "authors": [
    "Man LX",
    "Chang B"
   ],
   "journal": "Plastic and reconstructive surgery",
   "year": "2006",
   "volume": "117",
   "pages": "301-8",
   "pubtypes": [],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16955495",
   "doi": "10.1002/bdra.20288",
   "title": "Maternal severe migraine and risk of congenital limb deficiencies",
   "authors": [
    "Bánhidy F",
    "Acs N",
    "Horváth-Puhó E",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2006",
   "volume": "76",
   "pages": "592-601",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16433834",
   "doi": "10.1111/j.1600-0897.2005.00345.x",
   "title": "Prebreeding maternal immunostimulation with Freund's complete adjuvant reduces placental damage and distal limb defects caused by methylnitrosourea",
   "authors": [
    "Renee Prater M",
    "Zimmerman KL",
    "Laudermilch CL",
    "et al."
   ],
   "journal": "American journal of reproductive immunology (New York, N.Y. : 1989)",
   "year": "2006",
   "volume": "55",
   "pages": "145-55",
   "pubtypes": [
    "Comparative Study",
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16859833",
   "doi": "10.1016/j.neuroscience.2006.06.017",
   "title": "Prenatal exposure to thalidomide, altered vasculogenesis, and CNS malformations",
   "authors": [
    "Hallene KL",
    "Oby E",
    "Lee BJ",
    "et al."
   ],
   "journal": "Neuroscience",
   "year": "2006",
   "volume": "142",
   "pages": "267-83",
   "pubtypes": [
    "Comparative Study",
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16990227",
   "doi": "10.1080/03093640600731710",
   "title": "Prescription of the first prosthesis and later use in children with congenital unilateral upper limb deficiency: A systematic review",
   "authors": [
    "Meurs M",
    "Maathuis CG",
    "Lucas C",
    "et al."
   ],
   "journal": "Prosthetics and orthotics international",
   "year": "2006",
   "volume": "30",
   "pages": "165-73",
   "pubtypes": [
    "Meta-Analysis",
    "Systematic Review"
   ],
   "codes": [],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16377066",
   "doi": "10.1016/j.ejogrb.2005.09.017",
   "title": "Risk factors of preterm delivery at less than 35 weeks in patients with renal transplant",
   "authors": [
    "Kurata A",
    "Matsuda Y",
    "Tanabe K",
    "et al."
   ],
   "journal": "European journal of obstetrics, gynecology, and reproductive biology",
   "year": "2006",
   "volume": "128",
   "pages": "64-8",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16906563",
   "doi": "10.1002/ajmg.a.31402",
   "title": "Risk of limb deficiency defects associated with NAT1, NAT2, GSTT1, GSTM1, and NOS3 genetic variants, maternal smoking, and vitamin supplement intake",
   "authors": [
    "Carmichael SL",
    "Shaw GM",
    "Yang W",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2006",
   "volume": "140",
   "pages": "1915-22",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, Non-P.H.S.",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15990165",
   "doi": "10.1016/j.placenta.2005.04.003",
   "title": "Role of maternal dietary antioxidant supplementation in murine placental and fetal limb development",
   "authors": [
    "Prater MR",
    "Zimmerman KL",
    "Pinn LC",
    "et al."
   ],
   "journal": "Placenta",
   "year": "2006",
   "volume": "27",
   "pages": "502-9",
   "pubtypes": [
    "Research Support, N.I.H., Extramural"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16427249",
   "doi": "10.1016/j.reprotox.2005.11.007",
   "title": "Thalidomide embryopathy cases in Brazil after 1965",
   "authors": [
    "Paumgartten FJ",
    "Chahoud I"
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "2006",
   "volume": "22",
   "pages": "1-2",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16445798",
   "doi": "10.1111/j.1365-2133.2005.07083.x",
   "title": "Thalidomide, semen distribution, teratogenicity... and cost",
   "authors": [
    "Laffitte E"
   ],
   "journal": "The British journal of dermatology",
   "year": "2006",
   "volume": "154",
   "pages": "563; author reply 563-4",
   "pubtypes": [
    "Comment",
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "17151538",
   "doi": "10.1016/s0368-2315(06)76484-5",
   "title": "[Association of neonatal polydactyly and maternal glucose tolerance impairment in the Congolese environment]",
   "authors": [
    "Sengeyi MA",
    "Tandu-Umba B"
   ],
   "journal": "Journal de gynecologie, obstetrique et biologie de la reproduction",
   "year": "2006",
   "volume": "35",
   "pages": "813-9",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15637728",
   "doi": "10.1002/ajmg.a.30554",
   "title": "A novel GJA1 mutation causes oculodentodigital dysplasia without syndactyly",
   "authors": [
    "Vitiello C",
    "D'Adamo P",
    "Gentile F",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2005",
   "volume": "133A",
   "pages": "58-60",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16104005",
   "doi": "10.1002/bdra.20180",
   "title": "Combined chemotherapy and teratogenicity",
   "authors": [
    "Paskulin GA",
    "Gazzola Zen PR",
    "de Camargo Pinto LL",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2005",
   "volume": "73",
   "pages": "634-7",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2440",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15677727",
   "doi": "10.1242/dev.01613",
   "title": "Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb",
   "authors": [
    "Sagai T",
    "Hosoya M",
    "Mizushina Y",
    "et al."
   ],
   "journal": "Development (Cambridge, England)",
   "year": "2005",
   "volume": "132",
   "pages": "797-803",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16080182",
   "doi": "10.1002/bdra.20176",
   "title": "Placental improvement and reduced distal limb defects by maternal interferon-gamma injection in methylnitrosourea-exposed mice",
   "authors": [
    "Laudermilch CL",
    "Holladay SD",
    "Sponenberg DP",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2005",
   "volume": "73",
   "pages": "597-604",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15858818",
   "doi": "10.1002/dvdy.20409",
   "title": "Shh signaling in limb bud ectoderm: potential role in teratogen-induced postaxial ectrodactyly",
   "authors": [
    "Bell SM",
    "Schreiner CM",
    "Goetz JA",
    "et al."
   ],
   "journal": "Developmental dynamics : an official publication of the American Association of Anatomists",
   "year": "2005",
   "volume": "233",
   "pages": "313-25",
   "pubtypes": [
    "Research Support, N.I.H., Extramural",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16059857",
   "doi": "10.1197/j.jht.2005.04.005",
   "title": "Upper extremity function in children with congenital hand anomalies",
   "authors": [
    "Ho ES",
    "Clarke HM"
   ],
   "journal": "Journal of hand therapy : official journal of the American Society of Hand Therapists",
   "year": "2005",
   "volume": "18",
   "pages": "352-64",
   "pubtypes": [
    "Systematic Review"
   ],
   "codes": [],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "16224672",
   "doi": "10.1055/s-2005-872467",
   "title": "[Nation-wide registration of limb deficiencies in Germany]",
   "authors": [
    "Weber M",
    "Schröder S",
    "Berdel P",
    "et al."
   ],
   "journal": "Zeitschrift fur Orthopadie und ihre Grenzgebiete",
   "year": "2005",
   "volume": "143",
   "pages": "534-8",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "93322"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Isolated tibial hemimelia (prevalence at birth, Europe)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "14713331",
   "doi": "10.1089/152308604771978291",
   "title": "A novel hypothesis for thalidomide-induced limb teratogenesis: redox misregulation of the NF-kappaB pathway",
   "authors": [
    "Hansen JM",
    "Harris C"
   ],
   "journal": "Antioxidants & redox signaling",
   "year": "2004",
   "volume": "6",
   "pages": "1-14",
   "pubtypes": [
    "Editorial",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15617020",
   "doi": "10.1002/bdrb.20021",
   "title": "Effect in rats of simultaneous prenatal exposure to ochratoxin A and aflatoxin B1. I. Maternal toxicity and fetal malformations",
   "authors": [
    "Wangikar PB",
    "Dwivedi P",
    "Sinha N"
   ],
   "journal": "Birth defects research. Part B, Developmental and reproductive toxicology",
   "year": "2004",
   "volume": "71",
   "pages": "343-51",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14770404",
   "doi": "10.1002/uog.977",
   "title": "Fetal hydrops, associated with maternal propylthiouracil exposure, reversed by intrauterine therapy",
   "authors": [
    "Yanai N",
    "Shveiky D"
   ],
   "journal": "Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology",
   "year": "2004",
   "volume": "23",
   "pages": "198-201",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15108242",
   "doi": "10.1002/bdra.20019",
   "title": "Gestational ethanol exposure disrupts the expression of FGF8 and Sonic hedgehog during limb patterning",
   "authors": [
    "Chrisman K",
    "Kenney R",
    "Comin J",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2004",
   "volume": "70",
   "pages": "163-71",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14726182",
   "doi": "10.1016/S0140-6736(03)15279-8",
   "title": "Health of thalidomide victims and their progeny",
   "authors": [
    "McBride W"
   ],
   "journal": "Lancet (London, England)",
   "year": "2004",
   "volume": "363",
   "pages": "169",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14872406",
   "doi": "10.1086/382196",
   "title": "Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family",
   "authors": [
    "Niemann S",
    "Zhao C",
    "Pascu F",
    "et al."
   ],
   "journal": "American journal of human genetics",
   "year": "2004",
   "volume": "74",
   "pages": "558-63",
   "pubtypes": [],
   "codes": [
    "1027",
    "3301"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14994238",
   "doi": "10.1002/ajmg.a.20517",
   "title": "Limb deficiency defects, MSX1, and exposure to tobacco smoke",
   "authors": [
    "Carmichael SL",
    "Shaw GM",
    "Yang W",
    "et al."
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2004",
   "volume": "125A",
   "pages": "285-9",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, Non-P.H.S.",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15368555",
   "doi": "10.1002/bdra.20065",
   "title": "Maternal age and non-chromosomal birth defects, Atlanta--1968-2000: teenager or thirty-something, who is at risk?",
   "authors": [
    "Reefhuis J",
    "Honein MA"
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2004",
   "volume": "70",
   "pages": "572-9",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15314642",
   "doi": "10.1038/ng1414",
   "title": "Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome",
   "authors": [
    "Fan Y",
    "Esmail MA",
    "Ansley SJ",
    "et al."
   ],
   "journal": "Nature genetics",
   "year": "2004",
   "volume": "36",
   "pages": "989-93",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15549153",
   "doi": "",
   "title": "Partial duplication of 3q and distal deletion of 10q inherited from a maternal balanced translocation",
   "authors": [
    "Su PH",
    "Chen JY",
    "Chen SJ",
    "et al."
   ],
   "journal": "Journal of the Formosan Medical Association = Taiwan yi zhi",
   "year": "2004",
   "volume": "103",
   "pages": "853-7",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15526292",
   "doi": "10.1002/bdra.20082",
   "title": "Reduced birth defects caused by maternal immune stimulation in methylnitrosourea-exposed mice: association with placental improvement",
   "authors": [
    "Prater MR",
    "Zimmerman KL",
    "Ward DL",
    "et al."
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2004",
   "volume": "70",
   "pages": "862-9",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "15162308",
   "doi": "10.1055/s-2004-817872",
   "title": "Teratogenic mechanisms of longitudinal deficiency and cleft hand",
   "authors": [
    "Ogino T"
   ],
   "journal": "Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...",
   "year": "2004",
   "volume": "36",
   "pages": "108-16",
   "pubtypes": [],
   "codes": [
    "2440",
    "2913",
    "93320",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12620993",
   "doi": "10.1242/dev.00396",
   "title": "An I47L substitution in the HOXD13 homeodomain causes a novel human limb malformation by producing a selective loss of function",
   "authors": [
    "Caronia G",
    "Goodman FR",
    "McKeown CM",
    "et al."
   ],
   "journal": "Development (Cambridge, England)",
   "year": "2003",
   "volume": "130",
   "pages": "1701-12",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14632304",
   "doi": "10.1002/bdra.10078",
   "title": "Chorionic villus sampling: a distinctive teratogenic effect on fingers?",
   "authors": [
    "Golden CM",
    "Ryan LM",
    "Holmes LB"
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2003",
   "volume": "67",
   "pages": "557-62",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12773776",
   "doi": "10.1093/toxsci/kfg098",
   "title": "Comparing the effects of stage and duration of retinoic Acid exposure on amphibian limb development: chronic exposure results in mortality, not limb malformations",
   "authors": [
    "Degitz SJ",
    "Holcombe GW",
    "Kosian PA",
    "et al."
   ],
   "journal": "Toxicological sciences : an official journal of the Society of Toxicology",
   "year": "2003",
   "volume": "74",
   "pages": "139-46",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12749386",
   "doi": "10.1002/bdra.10001",
   "title": "Epidemiologic analysis of maternal factors and amniotic band defects",
   "authors": [
    "Werler MM",
    "Louik C",
    "Mitchell AA"
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2003",
   "volume": "67",
   "pages": "68-72",
   "pubtypes": [
    "Comparative Study",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12476458",
   "doi": "10.1002/ajmg.a.10731",
   "title": "Humeroradial synostosis, ulnar aplasia and oligodactyly, with contralateral amelia, in a child with prenatal cocaine exposure",
   "authors": [
    "Marles SL",
    "Reed M",
    "Evans JA"
   ],
   "journal": "American journal of medical genetics. Part A",
   "year": "2003",
   "volume": "116A",
   "pages": "85-9",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [
    "1027",
    "93320"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14745921",
   "doi": "10.1002/bdra.10100",
   "title": "Multiple congenital anomalies associated with in utero exposure of phenytoin: possible hypoxic ischemic mechanism?",
   "authors": [
    "Lyon HM",
    "Holmes LB",
    "Huang T"
   ],
   "journal": "Birth defects research. Part A, Clinical and molecular teratology",
   "year": "2003",
   "volume": "67",
   "pages": "993-6",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14577672",
   "doi": "",
   "title": "Multiple malformations in a male and maternal osteopathia strata with cranial sclerosis (OSCS)",
   "authors": [
    "Rott HD",
    "Krieg P",
    "Rütschle H",
    "et al."
   ],
   "journal": "Genetic counseling (Geneva, Switzerland)",
   "year": "2003",
   "volume": "14",
   "pages": "281-8",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "93323",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12843316",
   "doi": "10.1136/jmg.40.7.473",
   "title": "Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy",
   "authors": [
    "Kohlhase J",
    "Schubert L",
    "Liebers M",
    "et al."
   ],
   "journal": "Journal of medical genetics",
   "year": "2003",
   "volume": "40",
   "pages": "473-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "392",
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12745335",
   "doi": "10.1080/0960312031000098053",
   "title": "Role of environmental pollutants on immune functions, parasitic infections and limb malformations in marine toads and whistling frogs from Bermuda",
   "authors": [
    "Linzey D",
    "Burroughs J",
    "Hudson L",
    "et al."
   ],
   "journal": "International journal of environmental health research",
   "year": "2003",
   "volume": "13",
   "pages": "125-48",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, Non-P.H.S.",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12673646",
   "doi": "10.1002/pd.574",
   "title": "Second-trimester sonographic detection of short rib-polydactyly syndrome type II (Majewski) following an abnormal maternal serum biochemical screening result",
   "authors": [
    "Chen CP",
    "Chang TY",
    "Tzen CY",
    "et al."
   ],
   "journal": "Prenatal diagnosis",
   "year": "2003",
   "volume": "23",
   "pages": "353-5",
   "pubtypes": [
    "Case Reports",
    "Letter"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12930142",
   "doi": "10.1021/jm020079d",
   "title": "Thalidomide metabolites and analogues. 3. Synthesis and antiangiogenic activity of the teratogenic and TNFalpha-modulatory thalidomide analogue 2-(2,6-dioxopiperidine-3-yl)phthalimidine",
   "authors": [
    "Luzzio FA",
    "Mayorov AV",
    "Ng SS",
    "et al."
   ],
   "journal": "Journal of medicinal chemistry",
   "year": "2003",
   "volume": "46",
   "pages": "3793-9",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12644961",
   "doi": "10.4414/smw.2003.09947",
   "title": "Thalidomide: from tragedy to promise",
   "authors": [
    "von Moos R",
    "Stolz R",
    "Cerny T",
    "et al."
   ],
   "journal": "Swiss medical weekly",
   "year": "2003",
   "volume": "133",
   "pages": "77-87",
   "pubtypes": [
    "Historical Article",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12700363",
   "doi": "10.1203/01.PDR.0000069840.78984.76",
   "title": "The nitric oxide synthesis inhibitor Nomega-nitro-L-arginine methyl ester (L-NAME) causes limb defects in mouse fetuses: protective effect of acute hyperoxia",
   "authors": [
    "Tiboni GM",
    "Giampietro F",
    "Di Giulio C"
   ],
   "journal": "Pediatric research",
   "year": "2003",
   "volume": "54",
   "pages": "69-76",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12437147",
   "doi": "",
   "title": "Bio-alcamid: a novelty for reconstructive and cosmetic surgery",
   "authors": [
    "Pacini S",
    "Ruggiero M",
    "Morucci G",
    "et al."
   ],
   "journal": "Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia",
   "year": "2002",
   "volume": "107",
   "pages": "209-14",
   "pubtypes": [
    "Meta-Analysis"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "meta"
   ],
   "notes": [
    "PubMed search for systematic reviews and meta-analyses on the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12032320",
   "doi": "10.1073/pnas.112212199",
   "title": "Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly",
   "authors": [
    "Lettice LA",
    "Horikoshi T",
    "Heaney SJ",
    "et al."
   ],
   "journal": "Proceedings of the National Academy of Sciences of the United States of America",
   "year": "2002",
   "volume": "99",
   "pages": "7548-53",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12072798",
   "doi": "10.1097/00019605-200207000-00007",
   "title": "Microgastria-limb reduction anomaly with total amelia",
   "authors": [
    "Stewart C",
    "Stewart M",
    "Stewart F"
   ],
   "journal": "Clinical dysmorphology",
   "year": "2002",
   "volume": "11",
   "pages": "187-90",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2538"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Microgastria-limb reduction defect syndrome (cases/families, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "12242718",
   "doi": "10.1002/dvdy.10150",
   "title": "Misregulation of gene expression in the redox-sensitive NF-kappab-dependent limb outgrowth pathway by thalidomide",
   "authors": [
    "Hansen JM",
    "Gong SG",
    "Philbert M",
    "et al."
   ],
   "journal": "Developmental dynamics : an official publication of the American Association of Anatomists",
   "year": "2002",
   "volume": "225",
   "pages": "186-94",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12210472",
   "doi": "10.1002/tera.10083",
   "title": "Offspring of male and female parents with thalidomide embryopathy: birth defects and functional anomalies",
   "authors": [
    "Strömland K",
    "Philipson E",
    "Andersson Grönlund M"
   ],
   "journal": "Teratology",
   "year": "2002",
   "volume": "66",
   "pages": "115-21",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "living"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12357474",
   "doi": "10.1002/ajmg.10781",
   "title": "Teratogen-induced limb defects",
   "authors": [
    "Holmes LB"
   ],
   "journal": "American journal of medical genetics",
   "year": "2002",
   "volume": "112",
   "pages": "297-303",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11879981",
   "doi": "10.1016/s0378-4274(01)00522-7",
   "title": "Teratogenic assessment of carbadox in rats",
   "authors": [
    "Yoshimura H"
   ],
   "journal": "Toxicology letters",
   "year": "2002",
   "volume": "129",
   "pages": "115-8",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11861780",
   "doi": "10.1124/jpet.300.3.768",
   "title": "Thalidomide modulates nuclear redox status and preferentially depletes glutathione in rabbit limb versus rat limb",
   "authors": [
    "Hansen JM",
    "Harris KK",
    "Philbert MA",
    "et al."
   ],
   "journal": "The Journal of pharmacology and experimental therapeutics",
   "year": "2002",
   "volume": "300",
   "pages": "768-76",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12413903",
   "doi": "10.1006/dbio.2002.0817",
   "title": "The Fused toes (Ft) mouse mutation causes anteroposterior and dorsoventral polydactyly",
   "authors": [
    "Grotewold L",
    "Rüther U"
   ],
   "journal": "Developmental biology",
   "year": "2002",
   "volume": "251",
   "pages": "129-41",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12223419",
   "doi": "10.1242/dev.129.19.4635",
   "title": "The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome",
   "authors": [
    "Garrity DM",
    "Childs S",
    "Fishman MC"
   ],
   "journal": "Development (Cambridge, England)",
   "year": "2002",
   "volume": "129",
   "pages": "4635-45",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "392"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11956760",
   "doi": "10.1007/s00335-001-2142-7",
   "title": "The mouse Fused toes (Ft) mutation is the result of a 1.6-Mb deletion including the entire Iroquois B gene cluster",
   "authors": [
    "Peters T",
    "Ausmeier K",
    "Dildrop R",
    "et al."
   ],
   "journal": "Mammalian genome : official journal of the International Mammalian Genome Society",
   "year": "2002",
   "volume": "13",
   "pages": "186-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12455637",
   "doi": "",
   "title": "The mouse polydactylous mutation, luxate (lx), causes anterior shift of the anteroposterior border in the developing hindlimb bud",
   "authors": [
    "Yada Y",
    "Makino S",
    "Chigusa-Ishiwa S",
    "et al."
   ],
   "journal": "The International journal of developmental biology",
   "year": "2002",
   "volume": "46",
   "pages": "975-82",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11173961",
   "doi": "10.1159/000053894",
   "title": "Extreme elevation of maternal serum alpha-fetoprotein associated with mosaic trisomy 8 in a liveborn",
   "authors": [
    "Miller R",
    "Stephan MJ",
    "Hume RF",
    "et al."
   ],
   "journal": "Fetal diagnosis and therapy",
   "year": "2001",
   "volume": "16",
   "pages": "120-2",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11282181",
   "doi": "10.1016/s0188-4409(00)00260-5",
   "title": "Fetal amniotic adhesions. Their topographic concordance with regionally clustered malformations",
   "authors": [
    "Davies BR",
    "Giménez-Scherer JA",
    "Hernández-Sierra JF"
   ],
   "journal": "Archives of medical research",
   "year": "2001",
   "volume": "32",
   "pages": "48-61",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11381270",
   "doi": "10.1038/88925",
   "title": "Identification of the gene that, when mutated, causes the human obesity syndrome BBS4",
   "authors": [
    "Mykytyn K",
    "Braun T",
    "Carmi R",
    "et al."
   ],
   "journal": "Nature genetics",
   "year": "2001",
   "volume": "28",
   "pages": "188-91",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11581472",
   "doi": "10.1542/peds.108.4.e64",
   "title": "Limb deficiencies in newborn infants",
   "authors": [
    "McGuirk CK",
    "Westgate MN",
    "Holmes LB"
   ],
   "journal": "Pediatrics",
   "year": "2001",
   "volume": "108",
   "pages": "E64",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Isolated split hand-split foot malformation (prevalence at birth, United States)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "11337744",
   "doi": "10.1002/ajmg.1186",
   "title": "Maternal homozygosity for the common MTHFR mutation as a potential risk factor for offspring with limb defects",
   "authors": [
    "Shashi V",
    "Rickheim A",
    "Pettenati MJ"
   ],
   "journal": "American journal of medical genetics",
   "year": "2001",
   "volume": "100",
   "pages": "25-9",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12037261",
   "doi": "10.1093/phr/116.4.327",
   "title": "Maternal smoking and birth defects: validity of birth certificate data for effect estimation",
   "authors": [
    "Honein MA",
    "Paulozzi LJ",
    "Watkins ML"
   ],
   "journal": "Public health reports (Washington, D.C. : 1974)",
   "year": "2001",
   "volume": "116",
   "pages": "327-35",
   "pubtypes": [
    "Validation Study"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11418267",
   "doi": "10.1016/s0892-0362(01)00140-4",
   "title": "Neurobehavioral teratogenic effects of thalidomide in rats",
   "authors": [
    "Vorhees CV",
    "Weisenburger WP",
    "Minck DR"
   ],
   "journal": "Neurotoxicology and teratology",
   "year": "2001",
   "volume": "23",
   "pages": "255-64",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11754171",
   "doi": "10.1002/tera.1084",
   "title": "Stage-specific skeletal and visceral defects of the I(Kr)-blocker almokalant: further evidence for teratogenicity via a hypoxia-related mechanism",
   "authors": [
    "Sköld AC",
    "Wellfelt K",
    "Danielsson BR"
   ],
   "journal": "Teratology",
   "year": "2001",
   "volume": "64",
   "pages": "292-300",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11211946",
   "doi": "10.1111/j.8755-8920.2001.450107.x",
   "title": "TGFbeta2 in embryos with inborn anomalies: effect of maternal immunopotentiation",
   "authors": [
    "Ivnitsky I",
    "Torchinsky A",
    "Savion S",
    "et al."
   ],
   "journal": "American journal of reproductive immunology (New York, N.Y. : 1989)",
   "year": "2001",
   "volume": "45",
   "pages": "41-51",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "12068912",
   "doi": "",
   "title": "Thalidomide disaster: old wine in new bottles?",
   "authors": [
    "Bonta I"
   ],
   "journal": "Korot (Jerusalem : 1952)",
   "year": "2001",
   "volume": "15",
   "pages": "96-124",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14758882",
   "doi": "",
   "title": "Thalidomide: from teratogen to anti-angiogenic",
   "authors": [
    "Grover JK",
    "Vats K"
   ],
   "journal": "Indian journal of cancer",
   "year": "2001",
   "volume": "38",
   "pages": "22-32",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11466636",
   "doi": "10.1053/jhsu.2001.26121",
   "title": "The incidence and epidemiology of congenital upper limb anomalies: a total population study",
   "authors": [
    "Giele H",
    "Giele C",
    "Bower C",
    "et al."
   ],
   "journal": "The Journal of hand surgery",
   "year": "2001",
   "volume": "26",
   "pages": "628-34",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of Aussiehands (Australia)"
   ],
   "via": [
    "Aussiehands (Australia)"
   ]
  },
  {
   "pmid": "11607860",
   "doi": "10.1055/s-2001-17888",
   "title": "[On the history of the Contergan (thalidomide) catastrophe in the light of drug legislation]",
   "authors": [
    "Maio G"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "2001",
   "volume": "126",
   "pages": "1183-6",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11387997",
   "doi": "",
   "title": "[Teratology, 40 years after the thalidomide tragedy]",
   "authors": [
    "Burdan F"
   ],
   "journal": "Ginekologia polska",
   "year": "2001",
   "volume": "72",
   "pages": "93-100",
   "pubtypes": [
    "English Abstract",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11003055",
   "doi": "10.1016/s0024-3205(00)00636-6",
   "title": "A possible role of N-cadherin in thalidomide teratogenicity",
   "authors": [
    "Thiele A",
    "Thormann M",
    "Hofmann HJ",
    "et al."
   ],
   "journal": "Life sciences",
   "year": "2000",
   "volume": "67",
   "pages": "457-61",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10759272",
   "doi": "10.1111/j.1471-0528.2000.tb13272.x",
   "title": "Epidemiological assessment of misoprostol teratogenicity",
   "authors": [
    "Orioli IM",
    "Castilla EE"
   ],
   "journal": "BJOG : an international journal of obstetrics and gynaecology",
   "year": "2000",
   "volume": "107",
   "pages": "519-23",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10607376",
   "doi": "10.1002/(sici)1520-6866(2000)20:1<35::aid-tcm4>3.0.co;2-i",
   "title": "Evaluation of the developmental toxicity of thalidomide using frog embryo teratogenesis assay-xenopus (FETAX): biotransformation and detoxification",
   "authors": [
    "Fort DJ",
    "Stover EL",
    "Bantle JA",
    "et al."
   ],
   "journal": "Teratogenesis, carcinogenesis, and mutagenesis",
   "year": "2000",
   "volume": "20",
   "pages": "35-47",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10666009",
   "doi": "10.1016/s0024-3205(99)00571-8",
   "title": "Expression of adhesion receptors on rat limb bud cells and results of treatment with a thalidomide derivative",
   "authors": [
    "Thiel R",
    "Kastner U",
    "Neubert R"
   ],
   "journal": "Life sciences",
   "year": "2000",
   "volume": "66",
   "pages": "133-41",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10661908",
   "doi": "10.1002/(SICI)1096-9926(200003)61:3<189::AID-TERA6>3.0.CO;2-W",
   "title": "Hypothesis: thalidomide embryopathy-proposed mechanism of action",
   "authors": [
    "Stephens TD",
    "Fillmore BJ"
   ],
   "journal": "Teratology",
   "year": "2000",
   "volume": "61",
   "pages": "189-95",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11402670",
   "doi": "10.1556/AVet.48.2000.1.13",
   "title": "Interaction of Dithane M-45 (mancozeb) and lead acetate during a teratogenicity test in rats",
   "authors": [
    "Várnagy L",
    "Budai P",
    "Molnár E",
    "et al."
   ],
   "journal": "Acta veterinaria Hungarica",
   "year": "2000",
   "volume": "48",
   "pages": "113-24",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10855434",
   "doi": "10.1080/03093640008726517",
   "title": "Lower limb deficient children in The Netherlands: epidemiological aspects",
   "authors": [
    "Rijnders LJ",
    "Boonstra AM",
    "Groothoff JW",
    "et al."
   ],
   "journal": "Prosthetics and orthotics international",
   "year": "2000",
   "volume": "24",
   "pages": "13-8",
   "pubtypes": [],
   "codes": [
    "93323"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "published on the website of EUROCAT (EU RD Platform, JRC) (Italy)"
   ],
   "via": [
    "EUROCAT (EU RD Platform, JRC) (Italy)"
   ]
  },
  {
   "pmid": "10901110",
   "doi": "10.5271/sjweh.531",
   "title": "Maternal occupation in agriculture and risk of limb defects in Washington State, 1980-1993",
   "authors": [
    "Engel LS",
    "O'Meara ES",
    "Schwartz SM"
   ],
   "journal": "Scandinavian journal of work, environment & health",
   "year": "2000",
   "volume": "26",
   "pages": "193-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10799645",
   "doi": "10.1016/s0006-2952(99)00388-3",
   "title": "Mechanism of action in thalidomide teratogenesis",
   "authors": [
    "Stephens TD",
    "Bunde CJ",
    "Fillmore BJ"
   ],
   "journal": "Biochemical pharmacology",
   "year": "2000",
   "volume": "59",
   "pages": "1489-99",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10802661",
   "doi": "10.1038/75637",
   "title": "Mutation of a gene encoding a putative chaperonin causes McKusick-Kaufman syndrome",
   "authors": [
    "Stone DL",
    "Slavotinek A",
    "Bouffard GG",
    "et al."
   ],
   "journal": "Nature genetics",
   "year": "2000",
   "volume": "25",
   "pages": "79-82",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10826630",
   "doi": "10.1097/00019605-200009020-00015",
   "title": "Post-axial limb defects with maternal sodium valproate exposure",
   "authors": [
    "Pandya NA",
    "Jani BR"
   ],
   "journal": "Clinical dysmorphology",
   "year": "2000",
   "volume": "9",
   "pages": "143-4",
   "pubtypes": [
    "Case Reports",
    "Letter"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11131354",
   "doi": "10.1007/pl00008372",
   "title": "Preaxial polydactyly type 1 and severe language deficit in maternal uniparental disomy of chromosome 7",
   "authors": [
    "Potgieter S",
    "Matthijs G",
    "De Cock P",
    "et al."
   ],
   "journal": "European journal of pediatrics",
   "year": "2000",
   "volume": "159",
   "pages": "929-30",
   "pubtypes": [
    "Case Reports",
    "Comment",
    "Letter"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10706358",
   "doi": "",
   "title": "Prenatal exposure to valproic acid during pregnancy and limb deficiencies: a case-control study",
   "authors": [
    "Rodríguez-Pinilla E",
    "Arroyo I",
    "Fondevilla J",
    "et al."
   ],
   "journal": "American journal of medical genetics",
   "year": "2000",
   "volume": "90",
   "pages": "376-81",
   "pubtypes": [
    "Multicenter Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10753507",
   "doi": "10.1006/dbio.2000.9637",
   "title": "Targeted misexpression of constitutively active BMP receptor-IB causes bifurcation, duplication, and posterior transformation of digit in mouse limb",
   "authors": [
    "Zhang Z",
    "Yu X",
    "Zhang Y",
    "et al."
   ],
   "journal": "Developmental biology",
   "year": "2000",
   "volume": "220",
   "pages": "154-67",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, Non-P.H.S.",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11624679",
   "doi": "10.1177/030631200030001002",
   "title": "The redemption of thalidomide: standardizing the risk of birth defects",
   "authors": [
    "Timmermans S",
    "Leiter V"
   ],
   "journal": "Social studies of science",
   "year": "2000",
   "volume": "30",
   "pages": "41-71",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11050626",
   "doi": "10.1002/1096-8628(20001023)94:5<400::aid-ajmg11>3.0.co;2-q",
   "title": "Transverse limb defects associated with aorto-pulmonary vascular abnormalities: vascular disruption sequence or atypical presentation of Adams-Oliver syndrome?",
   "authors": [
    "Al-Sanna'a N",
    "Adatia I",
    "Teebi AS"
   ],
   "journal": "American journal of medical genetics",
   "year": "2000",
   "volume": "94",
   "pages": "400-4",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "974"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11061148",
   "doi": "",
   "title": "[The Contergan (Thalidomide) case. Catastrophic consequences]",
   "authors": [
    "Schulte-Wissermann H"
   ],
   "journal": "Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege",
   "year": "2000",
   "volume": "19",
   "pages": "360-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10229238",
   "doi": "10.1038/8466",
   "title": "Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity",
   "authors": [
    "Parman T",
    "Wiley MJ",
    "Wells PG"
   ],
   "journal": "Nature medicine",
   "year": "1999",
   "volume": "5",
   "pages": "582-5",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10488693",
   "doi": "10.1111/j.1600-0773.1999.tb00074.x",
   "title": "Interaction of thalidomide with DNA of rabbit embryos: a possible explanation for its immunosuppressant and teratogenic effects",
   "authors": [
    "Huang PH",
    "McBride WG",
    "Tuman WG"
   ],
   "journal": "Pharmacology & toxicology",
   "year": "1999",
   "volume": "85",
   "pages": "103-4",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10067994",
   "doi": "10.1302/0301-620x.81b1.8448",
   "title": "Longitudinal limb deficiencies and the sclerotomes. An analysis of 378 dysmelic malformations induced by thalidomide",
   "authors": [
    "McCredie J",
    "Willert HG"
   ],
   "journal": "The Journal of bone and joint surgery. British volume",
   "year": "1999",
   "volume": "81",
   "pages": "9-23",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10426292",
   "doi": "10.1038/11273",
   "title": "Mechanisms of thalidomide teratogenicity",
   "authors": [
    "Guenzler V"
   ],
   "journal": "Nature medicine",
   "year": "1999",
   "volume": "5",
   "pages": "853",
   "pubtypes": [
    "Comment",
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10364522",
   "doi": "10.1086/302467",
   "title": "Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster",
   "authors": [
    "Del Campo M",
    "Jones MC",
    "Veraksa AN",
    "et al."
   ],
   "journal": "American journal of human genetics",
   "year": "1999",
   "volume": "65",
   "pages": "104-10",
   "pubtypes": [
    "Case Reports",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9973085",
   "doi": "",
   "title": "Radiation-induced apoptosis and limb teratogenesis in embryonic mice",
   "authors": [
    "Wang B",
    "Fujita K",
    "Ohhira C",
    "et al."
   ],
   "journal": "Radiation research",
   "year": "1999",
   "volume": "151",
   "pages": "63-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10392652",
   "doi": "10.1177/026921559901300309",
   "title": "Shoulder joint replacement for osteoarthrosis in association with thalidomide-induced phocomelia",
   "authors": [
    "Newman RJ"
   ],
   "journal": "Clinical rehabilitation",
   "year": "1999",
   "volume": "13",
   "pages": "250-2",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10525208",
   "doi": "10.1002/(SICI)1096-9926(199911)60:5<306::AID-TERA11>3.0.CO;2-Y",
   "title": "Teratogen update: thalidomide: a review, with a focus on ocular findings and new potential uses",
   "authors": [
    "Miller MT",
    "Strömland K"
   ],
   "journal": "Teratology",
   "year": "1999",
   "volume": "60",
   "pages": "306-21",
   "pubtypes": [
    "Historical Article",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S.",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10327252",
   "doi": "",
   "title": "Terminal transverse limb defects with tethering and omphalocele in a 17 week fetus following first trimester misoprostol exposure",
   "authors": [
    "Genest DR",
    "Di Salvo D",
    "Rosenblatt MJ",
    "et al."
   ],
   "journal": "Clinical dysmorphology",
   "year": "1999",
   "volume": "8",
   "pages": "53-8",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10546102",
   "doi": "",
   "title": "The concurrence of ring constrictions in Adams-Oliver syndrome: additional evidence for vascular disruption as common pathogenetic mechanism",
   "authors": [
    "Keymolen K",
    "De Smet L",
    "Bracke P",
    "et al."
   ],
   "journal": "Genetic counseling (Geneva, Switzerland)",
   "year": "1999",
   "volume": "10",
   "pages": "295-300",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "295000",
    "974"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10487395",
   "doi": "10.2165/00002018-199921030-00002",
   "title": "The return of thalidomide: can birth defects be prevented?",
   "authors": [
    "Lary JM",
    "Daniel KL",
    "Erickson JD",
    "et al."
   ],
   "journal": "Drug safety",
   "year": "1999",
   "volume": "21",
   "pages": "161-9",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9860497",
   "doi": "10.1021/tx9801817",
   "title": "Chiral inversion and hydrolysis of thalidomide: mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites",
   "authors": [
    "Reist M",
    "Carrupt PA",
    "Francotte E",
    "et al."
   ],
   "journal": "Chemical research in toxicology",
   "year": "1998",
   "volume": "11",
   "pages": "1521-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11012189",
   "doi": "10.1002/stem.5530160720",
   "title": "Defective c-Mpl signaling in the syndrome of thrombocytopenia with absent radii",
   "authors": [
    "Ballmaier M",
    "Schulze H",
    "Cremer M",
    "et al."
   ],
   "journal": "Stem cells (Dayton, Ohio)",
   "year": "1998",
   "volume": "16 Suppl 2",
   "pages": "177-84",
   "pubtypes": [],
   "codes": [
    "3320",
    "93321"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "published on the website of German registry for congenital thrombocytopenia (Germany)"
   ],
   "via": [
    "German registry for congenital thrombocytopenia (Germany)"
   ]
  },
  {
   "pmid": "9825947",
   "doi": "10.2165/00002018-199819050-00001",
   "title": "Does thalidomide cause second generation birth defects?",
   "authors": [
    "Smithells D"
   ],
   "journal": "Drug safety",
   "year": "1998",
   "volume": "19",
   "pages": "339-41",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9839356",
   "doi": "10.1002/(SICI)1096-9926(199811)58:5<183::AID-TERA4>3.0.CO;2-L",
   "title": "Limb reduction defects in the A/J mouse strain associated with maternal blood loss",
   "authors": [
    "Fawcett LB",
    "Buck SJ",
    "Brent RL"
   ],
   "journal": "Teratology",
   "year": "1998",
   "volume": "58",
   "pages": "183-9",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9555583",
   "doi": "",
   "title": "Symbrachydactyly involving hands and feet",
   "authors": [
    "De Smet L",
    "Fabry G",
    "Fryns JP"
   ],
   "journal": "Genetic counseling (Geneva, Switzerland)",
   "year": "1998",
   "volume": "9",
   "pages": "23-7",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "1570"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Symbrachydactyly of hands and feet (cases/families, Worldwide)",
    "cited by Orphanet for Symbrachydactyly of hands and feet (point prevalence, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "9643709",
   "doi": "10.1016/S0140-6736(97)09038-7",
   "title": "Thalidomide: was the tragedy preventable?",
   "authors": [
    "Dally A"
   ],
   "journal": "Lancet (London, England)",
   "year": "1998",
   "volume": "351",
   "pages": "1197-9",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10326577",
   "doi": "10.1016/S0140-6736(05)61165-8",
   "title": "Was the thalidomide tragedy preventable?",
   "authors": [
    "Smithells D"
   ],
   "journal": "Lancet (London, England)",
   "year": "1998",
   "volume": "351",
   "pages": "1591",
   "pubtypes": [
    "Comment",
    "Historical Article",
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "10326578",
   "doi": "10.1016/S0140-6736(05)61166-X",
   "title": "Was the thalidomide tragedy preventable?",
   "authors": [
    "Critchley EM"
   ],
   "journal": "Lancet (London, England)",
   "year": "1998",
   "volume": "351",
   "pages": "1591",
   "pubtypes": [
    "Biography",
    "Comment",
    "Historical Article",
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9690766",
   "doi": "10.1016/s0306-9877(98)90003-2",
   "title": "Was tumour necrosis factor-alpha responsible for the fetal malformations associated with thalidomide in the early 1960s?",
   "authors": [
    "Argilés JM",
    "Carbó N",
    "López-Soriano FJ"
   ],
   "journal": "Medical hypotheses",
   "year": "1998",
   "volume": "50",
   "pages": "313-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9542226",
   "doi": "",
   "title": "[Children with limb reductions in a population of 25,193 malformed newborns: the recognized causes. ECEMC. The Spanish Collaborative Study of Congenital Malformations]",
   "authors": [
    "Martínez-Frías ML",
    "Bermejo E",
    "Paisán L",
    "et al."
   ],
   "journal": "Anales espanoles de pediatria",
   "year": "1998",
   "volume": "48",
   "pages": "49-53",
   "pubtypes": [
    "English Abstract",
    "Multicenter Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9407593",
   "doi": "10.1016/s0890-6238(97)00066-x",
   "title": "Exacerbation of acetazolamide teratogenesis by amiloride and its analogs active against Na+/H+ exchangers and Na+ channels",
   "authors": [
    "Bell SM",
    "Schreiner CM",
    "Resnick E",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "1997",
   "volume": "11",
   "pages": "823-31",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9065222",
   "doi": "10.2105/ajph.87.1.29",
   "title": "Maternal smoking during pregnancy and limb reduction malformations in Sweden",
   "authors": [
    "Källén K"
   ],
   "journal": "American journal of public health",
   "year": "1997",
   "volume": "87",
   "pages": "29-32",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9249924",
   "doi": "10.1002/(SICI)1520-6866(1997)17:1<I::AID-TCM1>3.0.CO;2-L",
   "title": "Never-ending tales of the mode of the teratogenic action of thalidomide",
   "authors": [
    "Neubert D"
   ],
   "journal": "Teratogenesis, carcinogenesis, and mutagenesis",
   "year": "1997",
   "volume": "17",
   "pages": "i-ii",
   "pubtypes": [
    "Comment",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9415679",
   "doi": "10.1002/(sici)1096-8628(19971219)73:3<251::aid-ajmg4>3.0.co;2-v",
   "title": "The return of thalidomide: are birth defects surveillance systems ready?",
   "authors": [
    "Yang Q",
    "Khoury MJ",
    "James LM",
    "et al."
   ],
   "journal": "American journal of medical genetics",
   "year": "1997",
   "volume": "73",
   "pages": "251-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9409866",
   "doi": "10.1002/(sici)1096-8628(1997)73:2<162::aid-ajmg10>3.0.co;2-s",
   "title": "VATERL: an epidemiologic analysis of risk factors",
   "authors": [
    "Rittler M",
    "Paz JE",
    "Castilla EE"
   ],
   "journal": "American journal of medical genetics",
   "year": "1997",
   "volume": "73",
   "pages": "162-9",
   "pubtypes": [
    "Multicenter Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8766141",
   "doi": "",
   "title": "A study on limb reduction defects in six European regions",
   "authors": [
    "Stoll C",
    "Calzolari E",
    "Cornel M",
    "et al."
   ],
   "journal": "Annales de genetique",
   "year": "1996",
   "volume": "39",
   "pages": "99-104",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Isolated split hand-split foot malformation (prevalence at birth, Europe)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "8538367",
   "doi": "10.1016/0024-3205(95)02290-2",
   "title": "Down-regulation of adhesion receptors on cells of primate embryos as a probable mechanism of the teratogenic action of thalidomide",
   "authors": [
    "Neubert R",
    "Hinz N",
    "Thiel R",
    "et al."
   ],
   "journal": "Life sciences",
   "year": "1996",
   "volume": "58",
   "pages": "295-316",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8667234",
   "doi": "",
   "title": "Inhibition of thalidomide teratogenicity by acetylsalicylic acid: evidence for prostaglandin H synthase-catalyzed bioactivation of thalidomide to a teratogenic reactive intermediate",
   "authors": [
    "Arlen RR",
    "Wells PG"
   ],
   "journal": "The Journal of pharmacology and experimental therapeutics",
   "year": "1996",
   "volume": "277",
   "pages": "1649-58",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8879085",
   "doi": "10.1002/(SICI)1096-9926(199605)53:5<283::AID-TERA1>3.0.CO;2-2",
   "title": "Mechanism of teratogenic action of thalidomide",
   "authors": [
    "Vaisman B"
   ],
   "journal": "Teratology",
   "year": "1996",
   "volume": "53",
   "pages": "283-4",
   "pubtypes": [
    "Letter",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8987155",
   "doi": "10.1002/(SICI)1096-9926(199609)54:3<126::AID-TERA2>3.0.CO;2-1",
   "title": "Mesonephros has a role in limb development and is related to thalidomide embryopathy",
   "authors": [
    "Smith DM",
    "Torres RD",
    "Stephens TD"
   ],
   "journal": "Teratology",
   "year": "1996",
   "volume": "54",
   "pages": "126-34",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37282195",
   "doi": "10.1046/j.1440-169X.1996.00007.x",
   "title": "Possible involvement of an acylation mechanism in thalidomide-induced teratogenesis of the newt (Pleurodeles waltl.)",
   "authors": [
    "Audit CO",
    "Eger K",
    "Aimar C"
   ],
   "journal": "Development, growth & differentiation",
   "year": "1996",
   "volume": "38",
   "pages": "47-57",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8896721",
   "doi": "10.1007/s002040050336",
   "title": "Stereoselective distribution of the teratogenic thalidomide analogue EM12 in the early embryo of marmoset monkey, Wistar rat and NMRI mouse",
   "authors": [
    "Schmahl HJ",
    "Dencker L",
    "Plum C",
    "et al."
   ],
   "journal": "Archives of toxicology",
   "year": "1996",
   "volume": "70",
   "pages": "749-56",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8793311",
   "doi": "10.1016/0376-8716(96)01231-8",
   "title": "Teratogenic effects of ethanol in the Quackenbush special mouse",
   "authors": [
    "Amini SA",
    "Dunkley PR",
    "Murdoch RN"
   ],
   "journal": "Drug and alcohol dependence",
   "year": "1996",
   "volume": "41",
   "pages": "61-9",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8792847",
   "doi": "10.1016/0300-483x(96)88183-2",
   "title": "Teratogenic effects of the demethylating agent 5-aza-2'-deoxycytidine in the Swiss Webster mouse",
   "authors": [
    "Branch S",
    "Francis BM",
    "Brownie CF",
    "et al."
   ],
   "journal": "Toxicology",
   "year": "1996",
   "volume": "112",
   "pages": "37-43",
   "pubtypes": [],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8538370",
   "doi": "10.1016/0024-3205(95)02293-7",
   "title": "Thalidomide derivatives and the immune system. 6. Effects of two derivatives with no obvious teratogenic potency on the pattern of integrins and other surface receptors on blood cells of marmosets",
   "authors": [
    "Nogueira AC",
    "Neubert R",
    "Felies A",
    "et al."
   ],
   "journal": "Life sciences",
   "year": "1996",
   "volume": "58",
   "pages": "337-48",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "9098920",
   "doi": "10.1002/(SICI)1096-9926(199612)54:6<273::AID-TERA1>3.0.CO;2-#",
   "title": "Thalidomide, a current teratogen in South America",
   "authors": [
    "Castilla EE",
    "Ashton-Prolla P",
    "Barreda-Mejia E",
    "et al."
   ],
   "journal": "Teratology",
   "year": "1996",
   "volume": "54",
   "pages": "273-7",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8997637",
   "doi": "",
   "title": "The teratogenic action of retinoic acid in rat congenic and recombinant inbred strains",
   "authors": [
    "Bílá V",
    "Kren V"
   ],
   "journal": "Folia biologica",
   "year": "1996",
   "volume": "42",
   "pages": "167-73",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "93322"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7479280",
   "doi": "10.1111/j.1365-3016.1995.tb00148.x",
   "title": "Maternal Lyme disease and congenital malformations: a cord blood serosurvey in endemic and control areas",
   "authors": [
    "Williams CL",
    "Strobino B",
    "Weinstein A",
    "et al."
   ],
   "journal": "Paediatric and perinatal epidemiology",
   "year": "1995",
   "volume": "9",
   "pages": "320-30",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8585581",
   "doi": "10.1002/ajmg.1320590428",
   "title": "Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring",
   "authors": [
    "Shaw GM",
    "O'Malley CD",
    "Wasserman CR",
    "et al."
   ],
   "journal": "American journal of medical genetics",
   "year": "1995",
   "volume": "59",
   "pages": "536-45",
   "pubtypes": [
    "Clinical Trial",
    "Randomized Controlled Trial",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7735509",
   "doi": "",
   "title": "Porencephaly and transverse limb defects following severe maternal trauma in early pregnancy",
   "authors": [
    "Viljoen DL"
   ],
   "journal": "Clinical dysmorphology",
   "year": "1995",
   "volume": "4",
   "pages": "75-8",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8574428",
   "doi": "10.1097/00019605-199510000-00013",
   "title": "Transverse limb deficiency, facial clefting and hypoxic renal damage: an association with treatment of maternal hypertension?",
   "authors": [
    "Hurst JA",
    "Houlston RS",
    "Roberts A",
    "et al."
   ],
   "journal": "Clinical dysmorphology",
   "year": "1995",
   "volume": "4",
   "pages": "359-63",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8157157",
   "doi": "10.1111/j.1469-8749.1994.tb11856.x",
   "title": "Autism in thalidomide embryopathy: a population study",
   "authors": [
    "Strömland K",
    "Nordin V",
    "Miller M",
    "et al."
   ],
   "journal": "Developmental medicine and child neurology",
   "year": "1994",
   "volume": "36",
   "pages": "351-6",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8186622",
   "doi": "10.1016/0890-6238(94)90065-5",
   "title": "Carpal and tarsal bone anomalies in mice induced by maternal treatment of Ara-C",
   "authors": [
    "Rahman ME",
    "Ishikawa H",
    "Watanabe Y",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "1994",
   "volume": "8",
   "pages": "41-7",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7856645",
   "doi": "10.1002/ajmg.1320530212",
   "title": "Chorionic villus sampling and transverse limb deficiencies: maternal age is not a confounder",
   "authors": [
    "Mastroiacovo P",
    "Botto LD"
   ],
   "journal": "American journal of medical genetics",
   "year": "1994",
   "volume": "53",
   "pages": "182-6",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8024468",
   "doi": "10.1007/s002040050055",
   "title": "Embryotoxic effects of thalidomide derivatives in the non-human primate Callithrix jacchus. 5. Lack of teratogenic effects of phthalimidophthalmide",
   "authors": [
    "Klug S",
    "Felies A",
    "Stürje H",
    "et al."
   ],
   "journal": "Archives of toxicology",
   "year": "1994",
   "volume": "68",
   "pages": "203-5",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7940403",
   "doi": "10.1002/tcm.1770140303",
   "title": "Embryotoxic effects of thalidomide derivatives in the non-human primate callithrix jacchus. IV. Teratogenicity of micrograms/kg doses of the EM12 enantiomers",
   "authors": [
    "Heger W",
    "Schmahl HJ",
    "Klug S",
    "et al."
   ],
   "journal": "Teratogenesis, carcinogenesis, and mutagenesis",
   "year": "1994",
   "volume": "14",
   "pages": "115-22",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "1027",
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8026630",
   "doi": "10.1006/dbio.1994.1198",
   "title": "Enhanced expression of limb malformations and axial skeleton alterations in legless mutants by transplacental exposure to retinoic acid",
   "authors": [
    "Scott WJ",
    "Collins MD",
    "Ernst AN",
    "et al."
   ],
   "journal": "Developmental biology",
   "year": "1994",
   "volume": "164",
   "pages": "277-89",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7851614",
   "doi": "",
   "title": "Evidence for teratogenicity of thalidomide using congenic and recombinant inbred rat strains",
   "authors": [
    "Bílá V",
    "Kren V"
   ],
   "journal": "Folia biologica",
   "year": "1994",
   "volume": "40",
   "pages": "161-71",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8042663",
   "doi": "10.1002/ajmg.1320500302",
   "title": "Familial crossed polysyndactyly",
   "authors": [
    "Goldstein DJ",
    "Kambouris M",
    "Ward RE"
   ],
   "journal": "American journal of medical genetics",
   "year": "1994",
   "volume": "50",
   "pages": "215-23",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2935"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Crossed polysyndactyly (cases/families, Worldwide)",
    "cited by Orphanet for Crossed polysyndactyly (point prevalence, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "7973488",
   "doi": "10.5271/sjweh.1412",
   "title": "Potential parental exposure to pesticides and limb reduction defects",
   "authors": [
    "Lin S",
    "Marshall EG",
    "Davidson GK"
   ],
   "journal": "Scandinavian journal of work, environment & health",
   "year": "1994",
   "volume": "20",
   "pages": "166-79",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7862054",
   "doi": "10.1016/0892-0362(94)90032-9",
   "title": "Potential teratogenic and neurodevelopmental consequences of coffee and caffeine exposure: a review on human and animal data",
   "authors": [
    "Nehlig A",
    "Debry G"
   ],
   "journal": "Neurotoxicology and teratology",
   "year": "1994",
   "volume": "16",
   "pages": "531-43",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8059428",
   "doi": "10.1002/tera.1420490317",
   "title": "The teratogenic effects of valproic acid in human chondrogenesis in vitro",
   "authors": [
    "Aulthouse AL",
    "Hitt DC"
   ],
   "journal": "Teratology",
   "year": "1994",
   "volume": "49",
   "pages": "208-17",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [
    "2440",
    "2879",
    "93321"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8186630",
   "doi": "10.1016/0890-6238(94)90072-8",
   "title": "Tibial hemimelia and tetralogy of Fallot associated with first trimester exposure to amantadine",
   "authors": [
    "Pandit PB",
    "Chitayat D",
    "Jefferies AL",
    "et al."
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "1994",
   "volume": "8",
   "pages": "89-92",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "93322"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8157136",
   "doi": "",
   "title": "Antimitotic and teratogenic effects of acyclic nucleotide analogues 1-(S)-(3-hydroxy-2-phosphonomethoxyethyl)cytosine (HPMPC) and 9-(2-phosphonomethoxyethyl) adenine (PMEA)",
   "authors": [
    "Bílá V",
    "Otová B",
    "Jelínek R",
    "et al."
   ],
   "journal": "Folia biologica",
   "year": "1993",
   "volume": "39",
   "pages": "150-61",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20301332",
   "doi": "",
   "title": "ESCO2 Spectrum Disorder",
   "authors": [
    "Adam MP",
    "Bick S",
    "Mirzaa GM",
    "et al."
   ],
   "journal": "",
   "year": "1993",
   "volume": "",
   "pages": "",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "3103"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "cited by Orphanet for Roberts syndrome (cases/families, Worldwide)",
    "cited by Orphanet for Roberts syndrome (point prevalence, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "8424019",
   "doi": "",
   "title": "Extent of duplication in lower-limb malformations suggests the time of the teratogenic insult",
   "authors": [
    "Packard DS Jr",
    "Levinsohn EM",
    "Hootnick DR"
   ],
   "journal": "Pediatrics",
   "year": "1993",
   "volume": "91",
   "pages": "411-3",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Review"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7692723",
   "doi": "10.1001/archpedi.1993.02160340048012",
   "title": "Intravenous pentazocine and methylphenidate abuse during pregnancy. Maternal lifestyle and infant outcome",
   "authors": [
    "Debooy VD",
    "Seshia MM",
    "Tenenbein M",
    "et al."
   ],
   "journal": "American journal of diseases of children (1960)",
   "year": "1993",
   "volume": "147",
   "pages": "1062-5",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8291530",
   "doi": "10.1002/ajmg.1320470733",
   "title": "Limb deficiencies, chorion villus sampling, and advanced maternal age",
   "authors": [
    "Halliday J",
    "Lumley J",
    "Sheffield LJ",
    "et al."
   ],
   "journal": "American journal of medical genetics",
   "year": "1993",
   "volume": "47",
   "pages": "1096-8",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8143629",
   "doi": "10.1289/ehp.93101s3269",
   "title": "Maternal factors, medications, and drug exposure in congenital limb reduction defects",
   "authors": [
    "Froster UG",
    "Baird PA"
   ],
   "journal": "Environmental health perspectives",
   "year": "1993",
   "volume": "101 Suppl 3",
   "pages": "269-74",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8322224",
   "doi": "10.1002/tera.1420470407",
   "title": "Mouse placenta: hemodynamics in the main maternal vessel and histopathologic changes induced by 2-methoxyethanol and 2-methoxyacetic acid following maternal dosing",
   "authors": [
    "Khera KS"
   ],
   "journal": "Teratology",
   "year": "1993",
   "volume": "47",
   "pages": "299-310",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8367833",
   "doi": "10.1002/tera.1420470612",
   "title": "Penetrance and expressivity of acetazolamide-ectrodactyly provide a method to define a right-left teratogenic gradient that differs between the C57BL/6J and WB/ReJ mouse strains",
   "authors": [
    "Biddle FG",
    "Mulholland LR",
    "Eales BA"
   ],
   "journal": "Teratology",
   "year": "1993",
   "volume": "47",
   "pages": "603-12",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8350947",
   "doi": "",
   "title": "Teratogenicity of cyclophosphamide in New Zealand white rabbits",
   "authors": [
    "Ujházy E",
    "Balonová T",
    "Durisová M",
    "et al."
   ],
   "journal": "Neoplasma",
   "year": "1993",
   "volume": "40",
   "pages": "45-9",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20301453",
   "doi": "",
   "title": "Tetra-Amelia Syndrome – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY",
   "authors": [
    "Adam MP",
    "Bick S",
    "Mirzaa GM",
    "et al."
   ],
   "journal": "",
   "year": "1993",
   "volume": "",
   "pages": "",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "3301"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "cited by Orphanet for Tetraamelia-multiple malformations syndrome (cases/families, Worldwide)",
    "cited by Orphanet for Tetraamelia-multiple malformations syndrome (point prevalence, Worldwide)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "8333272",
   "doi": "10.1111/j.1755-3768.1993.tb04997.x",
   "title": "Thalidomide embryopathy: revisited 27 years later",
   "authors": [
    "Strömland K",
    "Miller MT"
   ],
   "journal": "Acta ophthalmologica",
   "year": "1993",
   "volume": "71",
   "pages": "238-45",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8355115",
   "doi": "10.1016/s0022-3476(05)81739-1",
   "title": "Urethral obstruction sequence and lower limb deficiency: evidence for the vascular disruption hypothesis",
   "authors": [
    "Perez-Aytes A",
    "Graham JM",
    "Hersh JH",
    "et al."
   ],
   "journal": "The Journal of pediatrics",
   "year": "1993",
   "volume": "123",
   "pages": "398-405",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "8274232",
   "doi": "",
   "title": "[Polydactyly in 26,670 consecutive births. The clinical characteristics, prevalence and risk factors]",
   "authors": [
    "Pérez-Molina JJ",
    "Alfaro-Alfaro N",
    "López-Zermeño MC",
    "et al."
   ],
   "journal": "Boletin medico del Hospital Infantil de Mexico",
   "year": "1993",
   "volume": "50",
   "pages": "803-8",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1585375",
   "doi": "10.1016/0041-008x(92)90099-e",
   "title": "2-Methoxyacetic acid dosimetry-teratogenicity relationships in CD-1 mice exposed to 2-methoxyethanol",
   "authors": [
    "Clarke DO",
    "Duignan JM",
    "Welsch F"
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "1992",
   "volume": "114",
   "pages": "77-87",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1462245",
   "doi": "10.1002/tera.1420460505",
   "title": "A personal perspective on the thalidomide tragedy",
   "authors": [
    "Lenz W"
   ],
   "journal": "Teratology",
   "year": "1992",
   "volume": "46",
   "pages": "417-8",
   "pubtypes": [
    "Autobiography",
    "Biography",
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1481816",
   "doi": "10.1002/ajmg.1320440513",
   "title": "Constriction bands and limb reduction defects in two newborns with fetal ultrasound evidence for vascular disruption",
   "authors": [
    "Van Allen MI",
    "Siegel-Bartelt J",
    "Dixon J",
    "et al."
   ],
   "journal": "American journal of medical genetics",
   "year": "1992",
   "volume": "44",
   "pages": "598-604",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1562800",
   "doi": "10.1016/0890-6238(92)90022-l",
   "title": "Dependence of acetazolamide teratogenesis on fetal and not maternal genotypes",
   "authors": [
    "Beck SL",
    "Manabat N"
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "1992",
   "volume": "6",
   "pages": "63-7",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1554314",
   "doi": "10.1016/0003-9993(92)90015-o",
   "title": "Physiatric management of two neonates with limb deficiencies and prenatal cocaine exposure",
   "authors": [
    "Sheinbaum KA",
    "Badell A"
   ],
   "journal": "Archives of physical medicine and rehabilitation",
   "year": "1992",
   "volume": "73",
   "pages": "385-8",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1372357",
   "doi": "",
   "title": "Rare causes of elevated maternal serum alpha-fetoprotein. A report of three cases",
   "authors": [
    "Johnson VP"
   ],
   "journal": "The Journal of reproductive medicine",
   "year": "1992",
   "volume": "37",
   "pages": "93-6",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1577294",
   "doi": "10.1007/BF00164652",
   "title": "Refractive evaluation in thalidomide embryopathy",
   "authors": [
    "Strömland K",
    "Miller MT"
   ],
   "journal": "Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie",
   "year": "1992",
   "volume": "230",
   "pages": "140-9",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1635883",
   "doi": "10.1111/j.1365-3016.1992.tb00773.x",
   "title": "Risk factors in limb reduction defects",
   "authors": [
    "Stoll C",
    "Alembik Y",
    "Dott B",
    "et al."
   ],
   "journal": "Paediatric and perinatal epidemiology",
   "year": "1992",
   "volume": "6",
   "pages": "323-38",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1326133",
   "doi": "10.1002/tera.1420460314",
   "title": "Studies of the role of ischemia/reperfusion and superoxide anion radical production in the teratogenicity of cocaine",
   "authors": [
    "Fantel AG",
    "Barber CV",
    "Carda MB",
    "et al."
   ],
   "journal": "Teratology",
   "year": "1992",
   "volume": "46",
   "pages": "293-300",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1597253",
   "doi": "",
   "title": "Teratogenicity testing based on the interaction with a mutant allele",
   "authors": [
    "Bílá V",
    "Kren V"
   ],
   "journal": "Folia biologica",
   "year": "1992",
   "volume": "38",
   "pages": "40-7",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1952791",
   "doi": "",
   "title": "69,XXX karyotype in a malformed liveborn female. Maternal origin of triploidy",
   "authors": [
    "Galán F",
    "Orts F",
    "Aguilar MS",
    "et al."
   ],
   "journal": "Annales de genetique",
   "year": "1991",
   "volume": "34",
   "pages": "37-9",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1805430",
   "doi": "10.1002/tera.1420440602",
   "title": "Limb reduction defects in humans associated with prenatal isotretinoin exposure",
   "authors": [
    "Rizzo R",
    "Lammer EJ",
    "Parano E",
    "et al."
   ],
   "journal": "Teratology",
   "year": "1991",
   "volume": "44",
   "pages": "599-604",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2019959",
   "doi": "",
   "title": "Ocular motility in thalidomide embryopathy",
   "authors": [
    "Miller MT",
    "Strömland K"
   ],
   "journal": "Journal of pediatric ophthalmology and strabismus",
   "year": "1991",
   "volume": "28",
   "pages": "47-54",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1948762",
   "doi": "10.1002/tera.1420440304",
   "title": "Potentiating effect of caffeine on the teratogenicity of acetazolamide in C57BL/6J mice",
   "authors": [
    "Beck SL",
    "Urbano CM"
   ],
   "journal": "Teratology",
   "year": "1991",
   "volume": "44",
   "pages": "241-50",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1682706",
   "doi": "10.1016/0140-6736(91)92628-f",
   "title": "Prenatal diagnosis of limb-reduction defects due to maternal cocaine use",
   "authors": [
    "van den Anker JN",
    "Cohen-Overbeek TE",
    "Wladimiroff JW",
    "et al."
   ],
   "journal": "Lancet (London, England)",
   "year": "1991",
   "volume": "338",
   "pages": "1332",
   "pubtypes": [
    "Case Reports",
    "Letter"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1808819",
   "doi": "",
   "title": "Thalidomide embryopathy: a model for the study of congenital incomitant horizontal strabismus",
   "authors": [
    "Miller MT"
   ],
   "journal": "Transactions of the American Ophthalmological Society",
   "year": "1991",
   "volume": "89",
   "pages": "623-74",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1996196",
   "doi": "",
   "title": "[Holt-Oram syndrome]",
   "authors": [
    "Elek C",
    "Vitéz M",
    "Czeizel E"
   ],
   "journal": "Orvosi hetilap",
   "year": "1991",
   "volume": "132",
   "pages": "73-4, 77-8",
   "pubtypes": [
    "English Abstract",
    "Review"
   ],
   "codes": [
    "392"
   ],
   "topics": [
    "epidemiology",
    "review"
   ],
   "notes": [
    "cited by Orphanet for Holt-Oram syndrome (prevalence at birth, Hungary)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "1726510",
   "doi": "10.1016/0890-6238(90)90041-s",
   "title": "Characteristics of the limb malformations induced by maternal exposure to cadmium in the mouse",
   "authors": [
    "Padmanabhan R",
    "Hameed MS"
   ],
   "journal": "Reproductive toxicology (Elmsford, N.Y.)",
   "year": "1990",
   "volume": "4",
   "pages": "291-304",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440",
    "2879",
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2321168",
   "doi": "10.1002/tera.1420410216",
   "title": "Comments on \"Proposed Mechanisms of Action in Thalidomide Embryopathy\"",
   "authors": [
    "McCredie J"
   ],
   "journal": "Teratology",
   "year": "1990",
   "volume": "41",
   "pages": "239-42",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2321169",
   "doi": "10.1002/tera.1420410218",
   "title": "Comments on \"Proposed Mechanisms of Action in Thalidomide Embryopathy\"",
   "authors": [
    "Koch HP"
   ],
   "journal": "Teratology",
   "year": "1990",
   "volume": "41",
   "pages": "243-6",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2087687",
   "doi": "10.1002/tera.1420420611",
   "title": "Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide",
   "authors": [
    "Biddle FG"
   ],
   "journal": "Teratology",
   "year": "1990",
   "volume": "42",
   "pages": "659-70",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2308172",
   "doi": "",
   "title": "Research focuses on immunosuppressive effect, unknown teratogenic mechanism of thalidomide",
   "authors": [
    "Randall T"
   ],
   "journal": "JAMA",
   "year": "1990",
   "volume": "263",
   "pages": "1473",
   "pubtypes": [
    "News"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2309248",
   "doi": "10.1016/0378-4274(90)90024-g",
   "title": "Susceptibility to cyclophosphamide and thalidomide of fetal rat limb buds grafted in athymic (nude) mice",
   "authors": [
    "Shiota K",
    "Uwabe C",
    "Yamamoto M",
    "et al."
   ],
   "journal": "Toxicology letters",
   "year": "1990",
   "volume": "50",
   "pages": "309-18",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2164076",
   "doi": "10.1016/0266-7681_90_90125-n",
   "title": "Teratogenic relationship between polydactyly, syndactyly and cleft hand",
   "authors": [
    "Ogino T"
   ],
   "journal": "Journal of hand surgery (Edinburgh, Scotland)",
   "year": "1990",
   "volume": "15",
   "pages": "201-9",
   "pubtypes": [],
   "codes": [
    "2440",
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2361437",
   "doi": "10.1055/s-2008-1065108",
   "title": "[Presacral meningocele in thalidomide-induced embryopathy]",
   "authors": [
    "Bröcheler J",
    "Halfmann R"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1990",
   "volume": "115",
   "pages": "977-9",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2817779",
   "doi": "",
   "title": "\"Pure\" partial trisomy 3p due to the malsegregation of a balanced maternal translocation t (X;3) (p22.3;p21)",
   "authors": [
    "de Almeida JC",
    "Reis DF",
    "Llerena JC Jr",
    "et al."
   ],
   "journal": "Annales de genetique",
   "year": "1989",
   "volume": "32",
   "pages": "181-3",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2572064",
   "doi": "10.1002/tcm.1770090403",
   "title": "Cell cycle alterations and cell death in cyclophosphamide teratogenesis",
   "authors": [
    "Chernoff N",
    "Rogers JM",
    "Alles AJ",
    "et al."
   ],
   "journal": "Teratogenesis, carcinogenesis, and mutagenesis",
   "year": "1989",
   "volume": "9",
   "pages": "199-209",
   "pubtypes": [],
   "codes": [
    "1027"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2530150",
   "doi": "10.1016/0046-8177(89)90225-6",
   "title": "Limb body wall malformation complex: an embryologic etiology?",
   "authors": [
    "Hartwig NG",
    "Vermeij-Keers C",
    "De Vries HE",
    "et al."
   ],
   "journal": "Human pathology",
   "year": "1989",
   "volume": "20",
   "pages": "1071-7",
   "pubtypes": [
    "Case Reports",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2607306",
   "doi": "10.1136/jech.43.3.261",
   "title": "Maternal fertility, reproductive loss, and defective human embryos",
   "authors": [
    "Shiota K"
   ],
   "journal": "Journal of epidemiology and community health",
   "year": "1989",
   "volume": "43",
   "pages": "261-7",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2929123",
   "doi": "",
   "title": "Pregnancy outcome following first trimester exposure to cocaine in social users in Toronto, Canada",
   "authors": [
    "Graham K",
    "Dimitrakoudis D",
    "Pellegrini E",
    "et al."
   ],
   "journal": "Veterinary and human toxicology",
   "year": "1989",
   "volume": "31",
   "pages": "143-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2815516",
   "doi": "10.1136/vr.125.14.375",
   "title": "Teratogenic polydactyly in a halfbred foal",
   "authors": [
    "Dore MA"
   ],
   "journal": "The Veterinary record",
   "year": "1989",
   "volume": "125",
   "pages": "375-6",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2718140",
   "doi": "10.1002/tera.1420390107",
   "title": "Teratogenicity of 3,3-dimethyl-1-phenyltriazene in the rat: gross malformations including micrognathism",
   "authors": [
    "Frank AA",
    "Thompson DJ",
    "Kazacos EA"
   ],
   "journal": "Teratology",
   "year": "1989",
   "volume": "39",
   "pages": "53-61",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2487049",
   "doi": "",
   "title": "Thalidomide may inhibit proliferation of mesenchyme in human limb buds",
   "authors": [
    "Yasuda Y",
    "Nishimura H"
   ],
   "journal": "Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology",
   "year": "1989",
   "volume": "1",
   "pages": "247-54",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2492686",
   "doi": "10.1016/0378-4274(89)90155-0",
   "title": "The enantiomers of the teratogenic thalidomide analogue EM 12. 2. Chemical stability, stereoselectivity of metabolism and renal excretion in the marmoset monkey",
   "authors": [
    "Schmahl HJ",
    "Heger W",
    "Nau H"
   ],
   "journal": "Toxicology letters",
   "year": "1989",
   "volume": "45",
   "pages": "23-33",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2491005",
   "doi": "",
   "title": "The significance of genetic factors for thalidomide teratogenicity in the Norway rat",
   "authors": [
    "Bílá V",
    "Kren V"
   ],
   "journal": "Acta Universitatis Carolinae. Medica",
   "year": "1989",
   "volume": "35",
   "pages": "3-10",
   "pubtypes": [],
   "codes": [
    "2913",
    "93322",
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3067415",
   "doi": "10.1002/tera.1420380303",
   "title": "A short history of thalidomide embryopathy",
   "authors": [
    "Lenz W"
   ],
   "journal": "Teratology",
   "year": "1988",
   "volume": "38",
   "pages": "203-15",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3394109",
   "doi": "10.1002/tera.1420370407",
   "title": "Acetazolamide: maternal toxicity, pattern of malformations, and litter effect",
   "authors": [
    "Holmes LB",
    "Kawanishi H",
    "Munoz A"
   ],
   "journal": "Teratology",
   "year": "1988",
   "volume": "37",
   "pages": "335-42",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3067417",
   "doi": "10.1002/tera.1420380308",
   "title": "Clinical and basic science lessons from the thalidomide tragedy: what have we learned about the causes of limb defects?",
   "authors": [
    "Brent RL",
    "Holmes LB"
   ],
   "journal": "Teratology",
   "year": "1988",
   "volume": "38",
   "pages": "241-51",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "28614611",
   "doi": "10.1111/cga.1988.28.3.157",
   "title": "Effects of Antimutagens on the Teratogenicity of N-Methyl-N'-Nitro-N-Nitrosoguanidine in Mice",
   "authors": [
    "Morita Y",
    "Mizutani M"
   ],
   "journal": "Congenital anomalies",
   "year": "1988",
   "volume": "28",
   "pages": "157-167",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3411632",
   "doi": "10.1080/15287398809531178",
   "title": "Embryotoxic and teratogenic effects of selenium in the diet of mallards",
   "authors": [
    "Hoffman DJ",
    "Heinz GH"
   ],
   "journal": "Journal of toxicology and environmental health",
   "year": "1988",
   "volume": "24",
   "pages": "477-90",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3196154",
   "doi": "10.1007/BF00570141",
   "title": "Embryotoxic effects of thalidomide derivatives on the non-human primate Callithrix jacchus; 3. Teratogenic potency of the EM 12 enantiomers",
   "authors": [
    "Heger W",
    "Klug S",
    "Schmahl HJ",
    "et al."
   ],
   "journal": "Archives of toxicology",
   "year": "1988",
   "volume": "62",
   "pages": "205-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3250372",
   "doi": "10.1007/BF00288343",
   "title": "Embryotoxicity induced by alkylating agents: 5. Dose-response relationships of teratogenic effects of methylnitrosourea in mice",
   "authors": [
    "Platzek T",
    "Bochert G",
    "Pauli B",
    "et al."
   ],
   "journal": "Archives of toxicology",
   "year": "1988",
   "volume": "62",
   "pages": "411-23",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3418278",
   "doi": "10.1136/jech.42.1.1",
   "title": "Maternal drug histories and congenital malformations: limb reduction defects and oral clefts",
   "authors": [
    "Hill L",
    "Murphy M",
    "McDowall M",
    "et al."
   ],
   "journal": "Journal of epidemiology and community health",
   "year": "1988",
   "volume": "42",
   "pages": "1-7",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3067416",
   "doi": "10.1002/tera.1420380307",
   "title": "Proposed mechanisms of action in thalidomide embryopathy",
   "authors": [
    "Stephens TD"
   ],
   "journal": "Teratology",
   "year": "1988",
   "volume": "38",
   "pages": "229-39",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3351810",
   "doi": "",
   "title": "Questionable role of amniocentesis in the etiology of amniotic band formation. A case report",
   "authors": [
    "Lage JM",
    "VanMarter LJ",
    "Bieber FR"
   ],
   "journal": "The Journal of reproductive medicine",
   "year": "1988",
   "volume": "33",
   "pages": "71-3",
   "pubtypes": [
    "Case Reports",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3128249",
   "doi": "10.1007/BF00316633",
   "title": "Teratogenic interactions between methylmercury and mitomycin-C in mice",
   "authors": [
    "Inouye M",
    "Kajiwara Y"
   ],
   "journal": "Archives of toxicology",
   "year": "1988",
   "volume": "61",
   "pages": "192-5",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3143339",
   "doi": "10.1007/BF00570140",
   "title": "The enantiomers of the teratogenic thalidomide analogue EM 12: 1. Chiral inversion and plasma pharmacokinetics in the marmoset monkey",
   "authors": [
    "Schmahl HJ",
    "Nau H",
    "Neubert D"
   ],
   "journal": "Archives of toxicology",
   "year": "1988",
   "volume": "62",
   "pages": "200-4",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3227490",
   "doi": "10.1002/tera.1420380304",
   "title": "Why I doubted that thalidomide was the cause of the epidemic of limb defects of 1959 to 1961",
   "authors": [
    "Warkany J"
   ],
   "journal": "Teratology",
   "year": "1988",
   "volume": "38",
   "pages": "217-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3259330",
   "doi": "",
   "title": "[Use of the polydactyly-luxation syndrome in rats for studying the interaction of the genome with teratogenic factors]",
   "authors": [
    "Bílá V",
    "Kren V"
   ],
   "journal": "Sbornik lekarsky",
   "year": "1988",
   "volume": "90",
   "pages": "90-6",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3437608",
   "doi": "10.1111/j.1440-1819.1987.tb00403.x",
   "title": "Electroencephalographic study of 137 patients with thalidomide embryopathy",
   "authors": [
    "Kanno O"
   ],
   "journal": "The Japanese journal of psychiatry and neurology",
   "year": "1987",
   "volume": "41",
   "pages": "197-205",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3672373",
   "doi": "10.1002/tera.1420360117",
   "title": "Reduction of uterine blood flow by phenylephrine, an alpha-adrenergic agonist, in the day 11 pregnant rat: relationship to potentiation of acetazolamide teratogenesis",
   "authors": [
    "Ugen KE",
    "Scott WJ Jr"
   ],
   "journal": "Teratology",
   "year": "1987",
   "volume": "36",
   "pages": "133-41",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3110992",
   "doi": "10.1002/tera.1420350205",
   "title": "Teratogenicity and developmental toxicity of valproic acid in rats",
   "authors": [
    "Vorhees CV"
   ],
   "journal": "Teratology",
   "year": "1987",
   "volume": "35",
   "pages": "195-202",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3810656",
   "doi": "10.1016/0300-483x(87)90003-5",
   "title": "Teratogenicity of flubendazole in rats",
   "authors": [
    "Yoshimura H"
   ],
   "journal": "Toxicology",
   "year": "1987",
   "volume": "43",
   "pages": "133-8",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3662810",
   "doi": "10.1007/BF00295758",
   "title": "Teratologic studies on the Himalayan rabbit: new aspects of thalidomide-induced teratogenesis",
   "authors": [
    "Sterz H",
    "Nothdurft H",
    "Lexa P",
    "et al."
   ],
   "journal": "Archives of toxicology",
   "year": "1987",
   "volume": "60",
   "pages": "376-81",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3669113",
   "doi": "10.3109/15563658708992631",
   "title": "The nature of congenital limb defects induced in lambs by maternal ingestion of Veratrum californicum",
   "authors": [
    "Keeler RF",
    "Stuart LD"
   ],
   "journal": "Journal of toxicology. Clinical toxicology",
   "year": "1987",
   "volume": "25",
   "pages": "273-86",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3612097",
   "doi": "",
   "title": "[An unrecognized etiology of sexual ambiguity: Smith-Lemli-Opitz syndrome or a new entity?]",
   "authors": [
    "Le Merrer M",
    "Briard ML",
    "Chauvet ML"
   ],
   "journal": "Journal de genetique humaine",
   "year": "1987",
   "volume": "35",
   "pages": "187-93",
   "pubtypes": [
    "Case Reports",
    "English Abstract"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3146300",
   "doi": "10.1002/ajmg.1320250609",
   "title": "A cluster of Pallister-Hall syndrome cases, (congenital hypothalamic hamartoblastoma syndrome)",
   "authors": [
    "Graham JM Jr",
    "Saunders R",
    "Fratkin J",
    "et al."
   ],
   "journal": "American journal of medical genetics. Supplement",
   "year": "1986",
   "volume": "2",
   "pages": "53-63",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3775671",
   "doi": "10.1002/tera.1420340208",
   "title": "Acetazolamide teratogenesis in Wistar rats: potentiation and antagonism by adrenergic agents",
   "authors": [
    "Ugen KE",
    "Scott WJ Jr"
   ],
   "journal": "Teratology",
   "year": "1986",
   "volume": "34",
   "pages": "195-200",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3533366",
   "doi": "",
   "title": "Causes of limb reduction defects: the contribution of fetal constraint and/or vascular disruption",
   "authors": [
    "Graham JM Jr"
   ],
   "journal": "Clinics in perinatology",
   "year": "1986",
   "volume": "13",
   "pages": "575-91",
   "pubtypes": [
    "Review"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3469993",
   "doi": "10.1111/j.1479-828x.1986.tb01586.x",
   "title": "Congenital limb deficiency: maternal factors in pregnancy",
   "authors": [
    "Kricker A",
    "Elliott J",
    "Forrest J",
    "et al."
   ],
   "journal": "The Australian & New Zealand journal of obstetrics & gynaecology",
   "year": "1986",
   "volume": "26",
   "pages": "272-5",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2953123",
   "doi": "",
   "title": "Evidence for the intercalation of thalidomide into DNA: clue to the molecular mechanism of thalidomide teratogenicity?",
   "authors": [
    "Koch HP",
    "Czejka MJ"
   ],
   "journal": "Zeitschrift fur Naturforschung. C, Journal of biosciences",
   "year": "1986",
   "volume": "41",
   "pages": "1057-61",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3526621",
   "doi": "10.1002/tera.1420330304",
   "title": "Major limb malformations following intrauterine exposure to ethanol: two additional cases and literature review",
   "authors": [
    "Pauli RM",
    "Feldman PF"
   ],
   "journal": "Teratology",
   "year": "1986",
   "volume": "33",
   "pages": "273-80",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "1027",
    "2913"
   ],
   "topics": [
    "causes",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3738825",
   "doi": "10.1002/tera.1420330310",
   "title": "Prevention of caffeine-induced limb malformations by maternal adrenalectomy",
   "authors": [
    "Moriguchi M",
    "Scott WJ Jr"
   ],
   "journal": "Teratology",
   "year": "1986",
   "volume": "33",
   "pages": "319-22",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3945939",
   "doi": "10.1016/0041-008x(86)90449-7",
   "title": "Teratogen metabolism: thalidomide activation is mediated by cytochrome P-450",
   "authors": [
    "Braun AG",
    "Harding FA",
    "Weinreb SL"
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "1986",
   "volume": "82",
   "pages": "175-9",
   "pubtypes": [
    "Research Support, U.S. Gov't, Non-P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3082037",
   "doi": "10.1016/0041-008x(86)90278-4",
   "title": "Teratogenic effect of calcium edetate (CaEDTA) in rats and the protective effect of zinc",
   "authors": [
    "Brownie CF",
    "Brownie C",
    "Noden D",
    "et al."
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "1986",
   "volume": "82",
   "pages": "426-43",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3087378",
   "doi": "10.1016/0741-8329(86)90019-4",
   "title": "Teratogenic effects of lithium and ethanol in the developing fetus",
   "authors": [
    "Sharma A",
    "Rawat AK"
   ],
   "journal": "Alcohol (Fayetteville, N.Y.)",
   "year": "1986",
   "volume": "3",
   "pages": "101-6",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3533365",
   "doi": "",
   "title": "The thalidomide syndrome: risks of exposure and spectrum of malformations",
   "authors": [
    "Newman CG"
   ],
   "journal": "Clinics in perinatology",
   "year": "1986",
   "volume": "13",
   "pages": "555-73",
   "pubtypes": [
    "Case Reports",
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3936210",
   "doi": "10.1002/tera.1420320311",
   "title": "Cadmium-induced forelimb ectrodactyly: a proposed mechanism of teratogenesis",
   "authors": [
    "Feuston MH",
    "Scott WJ Jr"
   ],
   "journal": "Teratology",
   "year": "1985",
   "volume": "32",
   "pages": "407-19",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3007544",
   "doi": "",
   "title": "Congenital hand anomaly: etiology and associated malformations",
   "authors": [
    "Goldberg MJ",
    "Bartoshesky LE"
   ],
   "journal": "Hand clinics",
   "year": "1985",
   "volume": "1",
   "pages": "405-15",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2913",
    "93321",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4024099",
   "doi": "10.1016/0041-008x(85)90105-x",
   "title": "Developmental phase-specific and dose-related teratogenic effects of ethylene glycol monomethyl ether in CD-1 mice",
   "authors": [
    "Horton VL",
    "Sleet RB",
    "John-Greene JA",
    "et al."
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "1985",
   "volume": "80",
   "pages": "108-18",
   "pubtypes": [],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4035591",
   "doi": "10.1002/tera.1420320107",
   "title": "Maternal factors in congenital limb-reduction defects",
   "authors": [
    "Polednak AP",
    "Janerich DT"
   ],
   "journal": "Teratology",
   "year": "1985",
   "volume": "32",
   "pages": "41-50",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4085935",
   "doi": "",
   "title": "Possible involvement of the rat major histocompatibility complex in expression of the gene of the polydactyly-luxate syndrome in interaction with a teratogen",
   "authors": [
    "Bílá V",
    "Kren V"
   ],
   "journal": "Folia morphologica",
   "year": "1985",
   "volume": "33",
   "pages": "316-21",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4025389",
   "doi": "10.1002/ajmg.1320210319",
   "title": "Similarity of effects--experimental hyperthermia as a teratogen and maternal febrile illness associated with oromandibular and limb defects",
   "authors": [
    "Superneau DW",
    "Wertelecki W"
   ],
   "journal": "American journal of medical genetics",
   "year": "1985",
   "volume": "21",
   "pages": "575-80",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4019728",
   "doi": "",
   "title": "Temporomandibular malformations in the bonnet monkey (Macaca radiata) fetus following maternal ingestion of thalidomide",
   "authors": [
    "Newman LM",
    "Hendrickx AG"
   ],
   "journal": "Journal of craniofacial genetics and developmental biology",
   "year": "1985",
   "volume": "5",
   "pages": "147-57",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2866599",
   "doi": "10.1002/tcm.1770050304",
   "title": "Teratogen metabolism: spontaneous decay products of thalidomide and thalidomide analogues are not bioactivated by liver microsomes",
   "authors": [
    "Braun AG",
    "Weinreb SL"
   ],
   "journal": "Teratogenesis, carcinogenesis, and mutagenesis",
   "year": "1985",
   "volume": "5",
   "pages": "149-58",
   "pubtypes": [
    "Research Support, U.S. Gov't, Non-P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4035587",
   "doi": "10.1002/tera.1420320118",
   "title": "Teratogen update: clinical aspects of thalidomide embryopathy--a continuing preoccupation",
   "authors": [
    "Newman CG"
   ],
   "journal": "Teratology",
   "year": "1985",
   "volume": "32",
   "pages": "133-44",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2866598",
   "doi": "10.1002/tcm.1770050303",
   "title": "Teratogenic effects of carcinogenic agents on limb regeneration in the Japanese newt Cynops pyrrhogaster",
   "authors": [
    "Pfeiffer CJ",
    "Nagai T",
    "Fujimura M",
    "et al."
   ],
   "journal": "Teratogenesis, carcinogenesis, and mutagenesis",
   "year": "1985",
   "volume": "5",
   "pages": "137-47",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4035589",
   "doi": "10.1002/tera.1420320105",
   "title": "Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat",
   "authors": [
    "Ritter EJ",
    "Scott WJ Jr",
    "Randall JL",
    "et al."
   ],
   "journal": "Teratology",
   "year": "1985",
   "volume": "32",
   "pages": "25-31",
   "pubtypes": [
    "Comparative Study",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "3991661",
   "doi": "",
   "title": "Thalidomide embryopathy in Germany, 1959-1961",
   "authors": [
    "Lenz W"
   ],
   "journal": "Progress in clinical and biological research",
   "year": "1985",
   "volume": "163C",
   "pages": "77-83",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2857866",
   "doi": "10.1016/s0140-6736(85)92103-8",
   "title": "Thalidomide, orogenital ulcers, and risk of teratogenicity",
   "authors": [
    "Jenkins S",
    "Powell RJ",
    "Allen BR",
    "et al."
   ],
   "journal": "Lancet (London, England)",
   "year": "1985",
   "volume": "1",
   "pages": "511",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "2857357",
   "doi": "10.1016/s0140-6736(85)91068-2",
   "title": "Thalidomide, orogenital ulcers, and the risk of teratogenesis",
   "authors": [
    "Lehner T",
    "Sullivan FM"
   ],
   "journal": "Lancet (London, England)",
   "year": "1985",
   "volume": "1",
   "pages": "288-9",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4092878",
   "doi": "10.1016/0272-0590(85)90153-8",
   "title": "The teratogenic interaction of hydroxyurea and 5-bromodeoxyuridine examined with the aid of limb culture and image analysis",
   "authors": [
    "Kwasigroch TE",
    "Skalko RG"
   ],
   "journal": "Fundamental and applied toxicology : official journal of the Society of Toxicology",
   "year": "1985",
   "volume": "5",
   "pages": "1161-73",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4065215",
   "doi": "10.1538/expanim1978.34.3_295",
   "title": "[Teratogenic potentially of single dose of thalidomide in JW-NIBS rabbits]",
   "authors": [
    "Matsubara Y",
    "Mikami T"
   ],
   "journal": "Jikken dobutsu. Experimental animals",
   "year": "1985",
   "volume": "34",
   "pages": "295-302",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6436997",
   "doi": "10.1002/tera.1420300206",
   "title": "Acetazolamide teratogenesis: association of maternal respiratory acidosis and ectrodactyly in C57BL/6J mice",
   "authors": [
    "Weaver TE",
    "Scott WJ Jr"
   ],
   "journal": "Teratology",
   "year": "1984",
   "volume": "30",
   "pages": "187-93",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6436998",
   "doi": "10.1002/tera.1420300207",
   "title": "Acetazolamide teratogenesis: interaction of maternal metabolic and respiratory acidosis in the induction of ectrodactyly in C57BL/6J mice",
   "authors": [
    "Weaver TE",
    "Scott WJ Jr"
   ],
   "journal": "Teratology",
   "year": "1984",
   "volume": "30",
   "pages": "195-202",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6368281",
   "doi": "10.1016/0028-2243(84)90166-7",
   "title": "Classic illustration. Figure showing the relationship between malformations of the thalidomide type and the sales of thalidomide",
   "authors": [
    "Eskes TK"
   ],
   "journal": "European journal of obstetrics, gynecology, and reproductive biology",
   "year": "1984",
   "volume": "16",
   "pages": "365",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6503311",
   "doi": "10.1016/s0022-5193(84)80187-3",
   "title": "Differential inhibition of protein synthesis: a possible biochemical mechanism of thalidomide teratogenesis",
   "authors": [
    "Shull GE"
   ],
   "journal": "Journal of theoretical biology",
   "year": "1984",
   "volume": "110",
   "pages": "461-86",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6544320",
   "doi": "",
   "title": "Effect of exposure of pregnant rats to cadmium on prenatal and postnatal development of the young",
   "authors": [
    "Barański B"
   ],
   "journal": "Journal of hygiene, epidemiology, microbiology, and immunology",
   "year": "1984",
   "volume": "29",
   "pages": "253-62",
   "pubtypes": [],
   "codes": [
    "1027"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6147029",
   "doi": "10.1002/tcm.1770040306",
   "title": "Mouse limb bud development in submerged culture: quantitative assessment of the effects of in vivo exposure to retinoic acid",
   "authors": [
    "Kwasigroch TE",
    "Skalko RG",
    "Church JK"
   ],
   "journal": "Teratogenesis, carcinogenesis, and mutagenesis",
   "year": "1984",
   "volume": "4",
   "pages": "311-26",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440",
    "93458"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6732864",
   "doi": "10.1016/0006-2952(84)90415-5",
   "title": "Teratogen metabolism: activation of thalidomide and thalidomide analogues to products that inhibit the attachment of cells to concanavalin A coated plastic surfaces",
   "authors": [
    "Braun AG",
    "Weinreb SL"
   ],
   "journal": "Biochemical pharmacology",
   "year": "1984",
   "volume": "33",
   "pages": "1471-7",
   "pubtypes": [
    "Research Support, U.S. Gov't, Non-P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6828503",
   "doi": "",
   "title": "Bioactivation of thalidomide by a monkey liver fraction in a rat limb culture system",
   "authors": [
    "Shepard TH",
    "Shiota K"
   ],
   "journal": "Progress in clinical and biological research",
   "year": "1983",
   "volume": "110 Pt A",
   "pages": "377-85",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6652287",
   "doi": "",
   "title": "Clinical studies on teenage Brazilian victims of thalidomide",
   "authors": [
    "Schmidt M",
    "Salzano FM"
   ],
   "journal": "Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas",
   "year": "1983",
   "volume": "16",
   "pages": "105-9",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6867939",
   "doi": "10.1002/tera.1420270205",
   "title": "Congenital tibial aplasia with preaxial polydactyly: soft tissue anatomy as a clue to teratogenesis",
   "authors": [
    "Hootnick DR",
    "Packard DS Jr",
    "Levinsohn EM"
   ],
   "journal": "Teratology",
   "year": "1983",
   "volume": "27",
   "pages": "169-79",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913",
    "93322"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6298820",
   "doi": "",
   "title": "Effect of thalidomide-derivatives on limb development in culture",
   "authors": [
    "Neubert D",
    "Krowke R"
   ],
   "journal": "Progress in clinical and biological research",
   "year": "1983",
   "volume": "110 Pt A",
   "pages": "387-97",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6410529",
   "doi": "10.1002/tera.1420270306",
   "title": "Embryotoxicity and teratogenicity of thalidomide in rats",
   "authors": [
    "Parkhie M",
    "Webb M"
   ],
   "journal": "Teratology",
   "year": "1983",
   "volume": "27",
   "pages": "327-32",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6665735",
   "doi": "10.1002/tera.1420280307",
   "title": "Interaction of dietary zinc, genetic strain, and acetazolamide in teratogenesis in mice",
   "authors": [
    "Hackman RM",
    "Hurley LS"
   ],
   "journal": "Teratology",
   "year": "1983",
   "volume": "28",
   "pages": "355-68",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6667650",
   "doi": "10.1016/0378-3782(83)90101-9",
   "title": "Maternal diseases, alcohol consumption and smoking during pregnancy associated with reduction limb defects",
   "authors": [
    "Aro T"
   ],
   "journal": "Early human development",
   "year": "1983",
   "volume": "9",
   "pages": "49-57",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37281348",
   "doi": "10.1111/j.1440-169X.1983.00361.x",
   "title": "Pathogenesis of Thalidomide Teratogenesis in the Marmoset (Callithrix jacchus): Evidence Suggesting a Possible Trophic Influence of Cholinergic Nerves in Limb Morphogenesis: (thalidomide/neurotransmitters/cholinergic/nerves/anticholinergics/limb development)",
   "authors": [
    "McBRIDE WG",
    "Vardy PH"
   ],
   "journal": "Development, growth & differentiation",
   "year": "1983",
   "volume": "25",
   "pages": "361-373",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6409702",
   "doi": "10.1016/s0272-0590(83)80067-0",
   "title": "Teratogenesis of calcium valproate in rats",
   "authors": [
    "Ong LL",
    "Schardein JL",
    "Petrere JA",
    "et al."
   ],
   "journal": "Fundamental and applied toxicology : official journal of the Society of Toxicology",
   "year": "1983",
   "volume": "3",
   "pages": "121-6",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "37281200",
   "doi": "10.1111/j.1440-169X.1982.00099.x",
   "title": "Evidence of a Neural Inductive Phase in Limb Development: (induction/limb development/neural tube/neural crest/thalidomide)",
   "authors": [
    "Vardy PH",
    "Stokes PA",
    "McBRIDE WG"
   ],
   "journal": "Development, growth & differentiation",
   "year": "1982",
   "volume": "24",
   "pages": "99-114",
   "pubtypes": [],
   "codes": [
    "1027",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7075631",
   "doi": "10.1007/BF00442335",
   "title": "Holt Oram syndrome mistaken for thalidomide embryopathy--embryological considerations",
   "authors": [
    "Van Regemorter N",
    "Haumont D",
    "Kirkpatrick C",
    "et al."
   ],
   "journal": "European journal of pediatrics",
   "year": "1982",
   "volume": "138",
   "pages": "77-80",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "392",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7088198",
   "doi": "10.1007/BF00364900",
   "title": "Teratogenic activity of a hydrolytic thalidomide metabolite in mice",
   "authors": [
    "Kocher-Becker U",
    "Kocher W",
    "Ockenfels H"
   ],
   "journal": "Die Naturwissenschaften",
   "year": "1982",
   "volume": "69",
   "pages": "191-2",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7288383",
   "doi": "10.1002/jez.1402160111",
   "title": "Aspirin-induced teratogenesis: a unique pattern of cell death and subsequent polydactyly in the rat",
   "authors": [
    "Klein KL",
    "Scott WJ",
    "Wilson JG"
   ],
   "journal": "The Journal of experimental zoology",
   "year": "1981",
   "volume": "216",
   "pages": "107-12",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7196003",
   "doi": "",
   "title": "Azathioprine teratogenicity: review of the literature and case report",
   "authors": [
    "Williamson RA",
    "Karp LE"
   ],
   "journal": "Obstetrics and gynecology",
   "year": "1981",
   "volume": "58",
   "pages": "247-50",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7256658",
   "doi": "10.1002/tera.1420230310",
   "title": "Fetal ear malformations induced by maternal ingestion of thalidomide in the bonnet monkey (Macaca radiata)",
   "authors": [
    "Newman LM",
    "Hendrickx AG"
   ],
   "journal": "Teratology",
   "year": "1981",
   "volume": "23",
   "pages": "351-64",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7031539",
   "doi": "",
   "title": "In vivo assessment of the teratogenic potential of drugs in humans",
   "authors": [
    "Stern L"
   ],
   "journal": "Obstetrics and gynecology",
   "year": "1981",
   "volume": "58",
   "pages": "3S-8S",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7302870",
   "doi": "10.1002/tera.1420240103",
   "title": "Polydactyly and polysyndactyly induced by prenatal exposure to ethanol",
   "authors": [
    "West JR",
    "Black AC Jr",
    "Reimann PC",
    "et al."
   ],
   "journal": "Teratology",
   "year": "1981",
   "volume": "24",
   "pages": "13-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7229801",
   "doi": "10.1016/s0022-3476(81)80597-5",
   "title": "Preaxial polydactyly of the foot associated with early amnion rupture: evidence for mechanical teratogenesis?",
   "authors": [
    "Graham JM Jr",
    "Higginbottom MC",
    "Smith DW"
   ],
   "journal": "The Journal of pediatrics",
   "year": "1981",
   "volume": "98",
   "pages": "943-5",
   "pubtypes": [
    "Case Reports",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6261771",
   "doi": "",
   "title": "Studies on the hypothetical relationship of thalidomide-induced embryopathy and collagen biosynthesis",
   "authors": [
    "Flohé L",
    "Draeger E",
    "Frankus E",
    "et al."
   ],
   "journal": "Arzneimittel-Forschung",
   "year": "1981",
   "volume": "31",
   "pages": "315-20",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7245088",
   "doi": "10.1002/tera.1420230106",
   "title": "Teratogenesis of retinoic acid in rats: susceptible stages and suppression of retinoic acid-induced limb malformations by cycloheximide",
   "authors": [
    "Kistler A"
   ],
   "journal": "Teratology",
   "year": "1981",
   "volume": "23",
   "pages": "25-31",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6941308",
   "doi": "10.1073/pnas.78.4.2545",
   "title": "Thalidomide teratogenesis: evidence for a toxic arene oxide metabolite",
   "authors": [
    "Gordon GB",
    "Spielberg SP",
    "Blake DA",
    "et al."
   ],
   "journal": "Proceedings of the National Academy of Sciences of the United States of America",
   "year": "1981",
   "volume": "78",
   "pages": "2545-8",
   "pubtypes": [
    "Research Support, Non-U.S. Gov't",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7303822",
   "doi": "",
   "title": "Thalidomide-like malformations caused by Tween surfactant in mice",
   "authors": [
    "Kocher-Becker U",
    "Kocher W",
    "Ockenfels H"
   ],
   "journal": "Zeitschrift fur Naturforschung. Section C, Biosciences",
   "year": "1981",
   "volume": "36",
   "pages": "904-6",
   "pubtypes": [
    "Comparative Study",
    "Research Support, Non-U.S. Gov't"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7262093",
   "doi": "10.1007/BF00442988",
   "title": "The thalidomide disaster briefly revisited",
   "authors": [
    "Burgio GR"
   ],
   "journal": "European journal of pediatrics",
   "year": "1981",
   "volume": "136",
   "pages": "229-30",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7291126",
   "doi": "",
   "title": "The thalidomide embryopathy. An analysis from the UK",
   "authors": [
    "Quibell EP"
   ],
   "journal": "The Practitioner",
   "year": "1981",
   "volume": "225",
   "pages": "721-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7444807",
   "doi": "10.1002/tera.1420220207",
   "title": "A metabolite of a structural analog of thalidomide lacks teratogenic effect in pregnant rhesus monkeys",
   "authors": [
    "Scott WJ",
    "Wilson JG",
    "Helm FC"
   ],
   "journal": "Teratology",
   "year": "1980",
   "volume": "22",
   "pages": "183-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7385056",
   "doi": "10.1002/tera.1420210108",
   "title": "Ectopic pregnancy and myoma uteri: teratogenic effects and maternal characteristics",
   "authors": [
    "Matsunaga E",
    "Shiota K"
   ],
   "journal": "Teratology",
   "year": "1980",
   "volume": "21",
   "pages": "61-9",
   "pubtypes": [],
   "codes": [
    "1027"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7468292",
   "doi": "10.1111/j.1600-0447.1980.tb00618.x",
   "title": "Influence of maternal distress during pregnancy on fetal malformations",
   "authors": [
    "Blomberg S"
   ],
   "journal": "Acta psychiatrica Scandinavica",
   "year": "1980",
   "volume": "62",
   "pages": "315-30",
   "pubtypes": [],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6991189",
   "doi": "",
   "title": "Review of the treatment of thalidomide children with limb defeciency in Great Britain",
   "authors": [
    "Fletcher I"
   ],
   "journal": "Clinical orthopaedics and related research",
   "year": "1980",
   "volume": "",
   "pages": "18-25",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "prosthetics",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7389584",
   "doi": "10.3109/01480548009017835",
   "title": "Teratogenic activity in the mouse after oral administration of acetazolamide",
   "authors": [
    "Tellone CI",
    "Baldwin JK",
    "Sofia RD"
   ],
   "journal": "Drug and chemical toxicology",
   "year": "1980",
   "volume": "3",
   "pages": "83-98",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7360121",
   "doi": "",
   "title": "[Coincidence of a thalidomide-induced malformation and a lymphoma of high malignancy (author's transl)]",
   "authors": [
    "Miller A",
    "Schmidt CG",
    "Horwitz A",
    "et al."
   ],
   "journal": "Monatsschrift fur Kinderheilkunde",
   "year": "1980",
   "volume": "128",
   "pages": "27-9",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "7406666",
   "doi": "10.1002/ardp.19803130602",
   "title": "[Synthesis and teratogenic activity of some thalidomide analogous indane-1,3-diones (author's transl)]",
   "authors": [
    "Fickentscher K",
    "Halfmann U",
    "Köhler F"
   ],
   "journal": "Archiv der Pharmazie",
   "year": "1980",
   "volume": "313",
   "pages": "481-7",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6989723",
   "doi": "",
   "title": "[The spine in the thalidomide-embryopathy]",
   "authors": [
    "Ruffing L"
   ],
   "journal": "Fortschritte der Medizin",
   "year": "1980",
   "volume": "98",
   "pages": "405-9",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "524300",
   "doi": "10.1002/tera.1420200211",
   "title": "Morphological alterations in the developing fetal rat limb due to maternal injection of chlorambucil",
   "authors": [
    "Brummett ES",
    "Johnson EM"
   ],
   "journal": "Teratology",
   "year": "1979",
   "volume": "20",
   "pages": "279-87",
   "pubtypes": [],
   "codes": [
    "93323"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "451933",
   "doi": "10.1002/tera.1420190118",
   "title": "Thalidomide and lack of teratogenesis in Long-Evans rats",
   "authors": [
    "Chamberlain JG"
   ],
   "journal": "Teratology",
   "year": "1979",
   "volume": "19",
   "pages": "129",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "473085",
   "doi": "10.1002/tera.1420190310",
   "title": "The teratogenic activity of a thalidomide analogus EM12 in rats on a low-zinc diet",
   "authors": [
    "Jackson AJ",
    "Schumacher HJ"
   ],
   "journal": "Teratology",
   "year": "1979",
   "volume": "19",
   "pages": "341-4",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "226635",
   "doi": "",
   "title": "[A clinical and experimental study on teratogenic mechanism of cleft hand, polydactyly and syndactyly (author's transl)]",
   "authors": [
    "Ogino T"
   ],
   "journal": "Nihon Seikeigeka Gakkai zasshi",
   "year": "1979",
   "volume": "53",
   "pages": "535-43",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "2440",
    "2913",
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "583234",
   "doi": "",
   "title": "[Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers (author's transl)]",
   "authors": [
    "Blaschke G",
    "Kraft HP",
    "Fickentscher K",
    "et al."
   ],
   "journal": "Arzneimittel-Forschung",
   "year": "1979",
   "volume": "29",
   "pages": "1640-2",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "105418",
   "doi": "10.1002/tera.1420180314",
   "title": "Developmental staging and thalidomide teratogenicity in the green monkey (Cercopithecus aethiops)",
   "authors": [
    "Hendrickx AG",
    "Sawyer RH"
   ],
   "journal": "Teratology",
   "year": "1978",
   "volume": "18",
   "pages": "393-404",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "11648976",
   "doi": "",
   "title": "Full compensation for 20 thalidomide victims",
   "authors": [
    "Roper J"
   ],
   "journal": "Times (London, England : 1788)",
   "year": "1978",
   "volume": "",
   "pages": "1",
   "pubtypes": [
    "Newspaper Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "78126",
   "doi": "10.1016/s0140-6736(78)92436-4",
   "title": "Teratogenic action of thalidomide",
   "authors": [
    "McBride WG"
   ],
   "journal": "Lancet (London, England)",
   "year": "1978",
   "volume": "1",
   "pages": "1362",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "715730",
   "doi": "10.1002/tera.1420180213",
   "title": "Teratogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine in mice",
   "authors": [
    "Inouye M",
    "Murakami U"
   ],
   "journal": "Teratology",
   "year": "1978",
   "volume": "18",
   "pages": "263-7",
   "pubtypes": [],
   "codes": [
    "2440",
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "148445",
   "doi": "",
   "title": "The teratogenic effects of 5-fluoro-2-desoxyuridine (F.U.D.R.) on the Wistar rat fetus with particular reference to cleft palate",
   "authors": [
    "Ferguson MW"
   ],
   "journal": "Journal of anatomy",
   "year": "1978",
   "volume": "126",
   "pages": "37-49",
   "pubtypes": [],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "315193",
   "doi": "",
   "title": "Trisomy 3 (p23-pter) resulting from maternal translocation, t (3 ; 4)(p23 ; q35)",
   "authors": [
    "Schinzel A",
    "Hanson JW",
    "Pagon RA",
    "et al."
   ],
   "journal": "Annales de genetique",
   "year": "1978",
   "volume": "21",
   "pages": "168-71",
   "pubtypes": [
    "Case Reports",
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "93458"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "706700",
   "doi": "",
   "title": "[Ankylosing spinal changes in thalidomide embryopathies]",
   "authors": [
    "Ruffing L"
   ],
   "journal": "Verhandlungen der Deutschen Gesellschaft fur Rheumatologie",
   "year": "1978",
   "volume": "5",
   "pages": "427-31",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "568361",
   "doi": "",
   "title": "[The development of the postural and motor apparatus in juveniles with thalidomide embryopathy]",
   "authors": [
    "Matthiass HH",
    "Ruffing L"
   ],
   "journal": "Zeitschrift fur Orthopadie und ihre Grenzgebiete",
   "year": "1978",
   "volume": "116",
   "pages": "571-2",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "269906",
   "doi": "",
   "title": "A survey of thalidomide embryopathy in Taiwan",
   "authors": [
    "Yang TS",
    "Shen Cheng CC",
    "Wang CM"
   ],
   "journal": "Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association",
   "year": "1977",
   "volume": "76",
   "pages": "546-62",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "908424",
   "doi": "10.1007/BF01920195",
   "title": "Early foetal thrombosis induced by thalidomide in mouse: possible explanation for teratogenicity",
   "authors": [
    "Petter C"
   ],
   "journal": "Experientia",
   "year": "1977",
   "volume": "33",
   "pages": "1384-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "920161",
   "doi": "10.1111/j.1651-2227.1977.tb07969.x",
   "title": "Linear growth of children with limb deformities following exposure to thalidomide in utero",
   "authors": [
    "Brook CG",
    "Jarvis SN",
    "Newman CG"
   ],
   "journal": "Acta paediatrica Scandinavica",
   "year": "1977",
   "volume": "66",
   "pages": "673-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "594913",
   "doi": "10.1002/tera.1420160313",
   "title": "Non-confirmation of thalidomide induced teratogenesis in rats and mice",
   "authors": [
    "Scott WJ",
    "Fradkin R",
    "Wilson JG"
   ],
   "journal": "Teratology",
   "year": "1977",
   "volume": "16",
   "pages": "333-5",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "205132",
   "doi": "10.1002/ajmg.1320010108",
   "title": "Poland syndrome in British Columbia: incidence and reproductive experience of affected persons",
   "authors": [
    "McGillivray BC",
    "Lowry RB"
   ],
   "journal": "American journal of medical genetics",
   "year": "1977",
   "volume": "1",
   "pages": "65-74",
   "pubtypes": [],
   "codes": [
    "2911"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "cited by Orphanet for Poland syndrome (point prevalence, Canada)",
    "cited by Orphanet for Poland syndrome (prevalence at birth, Canada)"
   ],
   "via": [
    "Orphanet"
   ]
  },
  {
   "pmid": "402705",
   "doi": "10.1002/tera.1420150109",
   "title": "Teratogenic effects of retinoic acid in pigtail monkeys (Macaca nemestrina). I. General features",
   "authors": [
    "Fantel AG",
    "Shepard TH",
    "Newell-Morris LL",
    "et al."
   ],
   "journal": "Teratology",
   "year": "1977",
   "volume": "15",
   "pages": "65-71",
   "pubtypes": [
    "Research Support, U.S. Gov't, P.H.S."
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "331548",
   "doi": "10.1002/tera.1420160113",
   "title": "Thalidomide embryopathy",
   "authors": [
    "McBride WG"
   ],
   "journal": "Teratology",
   "year": "1977",
   "volume": "16",
   "pages": "79-82",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "70617",
   "doi": "10.1016/s0140-6736(77)90336-1",
   "title": "Thalidomide-type malformations and subsequent osteosarcoma",
   "authors": [
    "Teppo L",
    "Saxén E",
    "Tervo T",
    "et al."
   ],
   "journal": "Lancet (London, England)",
   "year": "1977",
   "volume": "2",
   "pages": "405",
   "pubtypes": [
    "Case Reports",
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "920119",
   "doi": "10.3109/17453677708988767",
   "title": "The spinal abnormalities in thalidomide embryopathy",
   "authors": [
    "Edwards DH",
    "Nichols PJ"
   ],
   "journal": "Acta orthopaedica Scandinavica",
   "year": "1977",
   "volume": "48",
   "pages": "273-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "560988",
   "doi": "10.1007/BF01922344",
   "title": "The teratogenic action of thalidomide on marine fish larvae",
   "authors": [
    "Hagström BE",
    "Lönning S"
   ],
   "journal": "Experientia",
   "year": "1977",
   "volume": "33",
   "pages": "1227-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "204553",
   "doi": "",
   "title": "[Embryology and etiology of the Poland and Amazone syndromes]",
   "authors": [
    "Mühlbauer W",
    "Wangerin K"
   ],
   "journal": "Handchirurgie",
   "year": "1977",
   "volume": "9",
   "pages": "147-52",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "2911"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1278626",
   "doi": "10.1111/j.1469-8749.1976.tb03628.x",
   "title": "Epilepsy: a neurological complication of thalidomide embryopathy",
   "authors": [
    "Stephenson JB"
   ],
   "journal": "Developmental medicine and child neurology",
   "year": "1976",
   "volume": "18",
   "pages": "189-97",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "55906",
   "doi": "10.1016/s0140-6736(76)90433-5",
   "title": "Letter: Neural crest, limb development, and thalidomide embryopathy",
   "authors": [
    "Gardner E",
    "O'Rahilly R"
   ],
   "journal": "Lancet (London, England)",
   "year": "1976",
   "volume": "1",
   "pages": "635-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "60606",
   "doi": "",
   "title": "Letter: Prenatal sex-hormone exposure and congenital limb-reduction defects",
   "authors": [],
   "journal": "Lancet (London, England)",
   "year": "1976",
   "volume": "2",
   "pages": "372-3",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "947085",
   "doi": "10.1016/0306-9877(76)90064-5",
   "title": "Mechanism of the teratogenic effect of thalidomide",
   "authors": [
    "McCredie J"
   ],
   "journal": "Medical hypotheses",
   "year": "1976",
   "volume": "2",
   "pages": "63-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1258925",
   "doi": "10.1016/s0002-9378(16)33334-8",
   "title": "Teratogenic effects of ethyl alcohol administered to pregnant mice",
   "authors": [
    "Kronick JB"
   ],
   "journal": "American journal of obstetrics and gynecology",
   "year": "1976",
   "volume": "124",
   "pages": "676-80",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "61456",
   "doi": "10.1016/s0140-6736(76)90618-8",
   "title": "Thalidomide and female genital malformations",
   "authors": [
    "Hoffmann W",
    "Grospietsch G",
    "Kuhn W"
   ],
   "journal": "Lancet (London, England)",
   "year": "1976",
   "volume": "2",
   "pages": "794",
   "pubtypes": [
    "Letter"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "61093",
   "doi": "",
   "title": "Thalidomide in America: a brush with tragedy",
   "authors": [
    "McFadyen RE"
   ],
   "journal": "Clio medica (Amsterdam, Netherlands)",
   "year": "1976",
   "volume": "11",
   "pages": "79-93",
   "pubtypes": [
    "Clinical Trial",
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1251664",
   "doi": "",
   "title": "[A case of complete amelia in a newborn infant. (Contribution on the etiology of breech presentation)]",
   "authors": [
    "Lacreta O",
    "Maretti M",
    "Vitiello N",
    "et al."
   ],
   "journal": "Zentralblatt fur Gynakologie",
   "year": "1976",
   "volume": "98",
   "pages": "45-51",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "1027"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1010296",
   "doi": "",
   "title": "[Genital malformations in thalidomide-damaged girls (author's transl)]",
   "authors": [
    "Hoffmann W",
    "Grospietsch G",
    "Kuhn W"
   ],
   "journal": "Geburtshilfe und Frauenheilkunde",
   "year": "1976",
   "volume": "36",
   "pages": "1066-70",
   "pubtypes": [
    "Case Reports",
    "English Abstract"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1027660",
   "doi": "",
   "title": "[Problems of treating the clubhand in dysmelia syndrome (thalidomide-embryopathy)]",
   "authors": [
    "Ruffing L",
    "Hertel E"
   ],
   "journal": "Handchirurgie",
   "year": "1976",
   "volume": "8",
   "pages": "211-4",
   "pubtypes": [
    "English Abstract"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "988595",
   "doi": "",
   "title": "[Teratogenic effect and stereospecificity of a thalidomide metabolite]",
   "authors": [
    "Ockenfels H",
    "Köhler F",
    "Meise W"
   ],
   "journal": "Die Pharmazie",
   "year": "1976",
   "volume": "31",
   "pages": "492-3",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1150705",
   "doi": "",
   "title": "Clinical and experimental studies of the congenital constriction band syndrome, with an emphasis on its etiology",
   "authors": [
    "Kino Y"
   ],
   "journal": "The Journal of bone and joint surgery. American volume",
   "year": "1975",
   "volume": "57",
   "pages": "636-43",
   "pubtypes": [],
   "codes": [
    "295000"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1243570",
   "doi": "10.1001/jama.231.1.62",
   "title": "Limb malformations following maternal use of haloperidol",
   "authors": [
    "McCullar FW",
    "Heggeness L"
   ],
   "journal": "JAMA",
   "year": "1975",
   "volume": "231",
   "pages": "62-4",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1138405",
   "doi": "10.1002/tera.1420110104",
   "title": "Teratogenesis of acetazolamide in the CBA/J and SWV strains of mice. I. Teratology",
   "authors": [
    "Biddle FG"
   ],
   "journal": "Teratology",
   "year": "1975",
   "volume": "11",
   "pages": "31-6",
   "pubtypes": [
    "Comparative Study"
   ],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1138406",
   "doi": "10.1002/tera.1420110105",
   "title": "Teratogenesis of acetazolamide in the CBA/J and SWV strains of mice. II. Genetic control of the teratogenic response",
   "authors": [
    "Biddle FG"
   ],
   "journal": "Teratology",
   "year": "1975",
   "volume": "11",
   "pages": "37-46",
   "pubtypes": [],
   "codes": [
    "2440"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "1170484",
   "doi": "",
   "title": "[Phocomelia and agenesis of the penis in a newborn infant. Possible teratogenic role of a drug taken by the mother during pregnancy]",
   "authors": [
    "Di Battista C",
    "Laudizi L",
    "Tamborino G"
   ],
   "journal": "Minerva pediatrica",
   "year": "1975",
   "volume": "27",
   "pages": "675-9",
   "pubtypes": [],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4460011",
   "doi": "10.1159/000136489",
   "title": "Teratogenicity and embryotoxicity of thalidomide and 3-aza-thalidomide in mice",
   "authors": [
    "Fickentscher K",
    "Köhler F"
   ],
   "journal": "Pharmacology",
   "year": "1974",
   "volume": "11",
   "pages": "193-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4549801",
   "doi": "10.5794/jjoms.20.45",
   "title": "[Observation of 22 cases of children with malformation of the arms and so-called thalidomide syndrome from the dental viewpoint (author's transl)]",
   "authors": [
    "Kunikiyo Y",
    "Masuda M",
    "Nasuno S",
    "et al."
   ],
   "journal": "Nihon Koku Geka Gakkai zasshi",
   "year": "1974",
   "volume": "20",
   "pages": "45-8",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4280665",
   "doi": "",
   "title": "[Proceedings: Changes of the shoulder joints in distal ectromelia in the scope of thalidomide embryopathy]",
   "authors": [
    "Ruffing L"
   ],
   "journal": "Zeitschrift fur Orthopadie und ihre Grenzgebiete",
   "year": "1974",
   "volume": "112",
   "pages": "1003-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4620254",
   "doi": "",
   "title": "[The fawn rabbit of Burgundy in teratology. Spontaneous malformations and malformations provoked by thalidomide]",
   "authors": [
    "Pasquet J"
   ],
   "journal": "Biologie medicale",
   "year": "1974",
   "volume": "3",
   "pages": "149-77",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4357023",
   "doi": "10.1136/jech.27.3.188",
   "title": "A test for space clustering and its application to congenital limb defects in Cardiff",
   "authors": [
    "Lloyd S",
    "Roberts CJ"
   ],
   "journal": "British journal of preventive & social medicine",
   "year": "1973",
   "volume": "27",
   "pages": "188-91",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4199118",
   "doi": "10.1002/tera.1420070206",
   "title": "Appendicular skeletal and visceral malformations induced by thalidomide in bonnet monkeys",
   "authors": [
    "Hendrickx AG",
    "Newman L"
   ],
   "journal": "Teratology",
   "year": "1973",
   "volume": "7",
   "pages": "151-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4714341",
   "doi": "10.1016/0041-008x(73)90165-8",
   "title": "Cardiovascular malformations in the chick embryo induced by thalidomide",
   "authors": [
    "Gilani SH"
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "1973",
   "volume": "25",
   "pages": "77-83",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4774456",
   "doi": "",
   "title": "Polydactyly of the thumb: incidence, etiology, classification and treatment",
   "authors": [
    "Palmieri TJ"
   ],
   "journal": "Bulletin of the Hospital for Joint Diseases",
   "year": "1973",
   "volume": "34",
   "pages": "200-21",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "epidemiology"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4352251",
   "doi": "10.1136/jech.27.1.67-a",
   "title": "Space-time clustering of limb defects in Cardiff",
   "authors": [
    "Lloyd S",
    "Roberts CJ"
   ],
   "journal": "British journal of preventive & social medicine",
   "year": "1973",
   "volume": "27",
   "pages": "67",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4207404",
   "doi": "10.1159/000460334",
   "title": "The sensitive period and malformation syndrome produced by thalidomide in crab-eating monkey (Macaca fascicularis)",
   "authors": [
    "Hendrickx AG"
   ],
   "journal": "Journal of medical primatology",
   "year": "1973",
   "volume": "2",
   "pages": "267-76",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4724009",
   "doi": "",
   "title": "[Crocodile tears in thalidomide embryopathy]",
   "authors": [
    "Trieschmann W"
   ],
   "journal": "Klinische Monatsblatter fur Augenheilkunde",
   "year": "1973",
   "volume": "162",
   "pages": "546-50",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4571160",
   "doi": "",
   "title": "Chemical structure and teratogenic properties. 3. A review of available data on structure-activity relationships and mechanism of action of thalidomide analogues",
   "authors": [
    "Jönsson NA"
   ],
   "journal": "Acta pharmaceutica Suecica",
   "year": "1972",
   "volume": "9",
   "pages": "521-42",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4656561",
   "doi": "",
   "title": "Chemical structure and teratogenic properties. IV. An outline of a chemical hypothesis for the teratogenic action of thalidomide",
   "authors": [
    "Jönsson NA"
   ],
   "journal": "Acta pharmaceutica Suecica",
   "year": "1972",
   "volume": "9",
   "pages": "543-62",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5041198",
   "doi": "10.1016/0012-1606(72)90126-1",
   "title": "Human teratogenesis: invitro studies on thalidomide-inhibited chondrogenesis",
   "authors": [
    "Lash JW",
    "Saxén L"
   ],
   "journal": "Developmental biology",
   "year": "1972",
   "volume": "28",
   "pages": "61-70",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4627159",
   "doi": "",
   "title": "Limb reduction anomalies induced in the marmoset by thalidomide",
   "authors": [
    "Hamilton WJ",
    "Poswillo DE"
   ],
   "journal": "Journal of anatomy",
   "year": "1972",
   "volume": "111",
   "pages": "505-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4623448",
   "doi": "10.1002/tera.1420050213",
   "title": "The teratogenic activity of a thalidomide analogue, EM 12 in rabbits, rats, and monkeys",
   "authors": [
    "Schumacher HJ",
    "Terapane J",
    "Jordan RL",
    "et al."
   ],
   "journal": "Teratology",
   "year": "1972",
   "volume": "5",
   "pages": "233-40",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4256053",
   "doi": "10.1002/tera.1420040405",
   "title": "A morphological and histochemical study of thalidomide-induced upper limb malformations in rabbit fetuses",
   "authors": [
    "Nudleman KL",
    "Travill AA"
   ],
   "journal": "Teratology",
   "year": "1971",
   "volume": "4",
   "pages": "409-25",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5100423",
   "doi": "10.1056/NEJM197103042840906",
   "title": "The thalidomide tragedy in Germany: the end of a historic medicolegal trial",
   "authors": [
    "Curran WJ"
   ],
   "journal": "The New England journal of medicine",
   "year": "1971",
   "volume": "284",
   "pages": "481-2",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5104050",
   "doi": "10.1007/BF02137287",
   "title": "[Compensation of the teratogenic effect of a thalidomide metabolite using L-glutamic acid]",
   "authors": [
    "Köhler F",
    "Ockenfels H"
   ],
   "journal": "Experientia",
   "year": "1971",
   "volume": "27",
   "pages": "421-2",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5556452",
   "doi": "10.1007/BF02136953",
   "title": "[Intermolecular interaction of folic acid with N-phthaloyl-DL-glutamic acid. Teratogenic effect of thalidomide]",
   "authors": [
    "Eckert T",
    "Dörr NW"
   ],
   "journal": "Experientia",
   "year": "1971",
   "volume": "27",
   "pages": "671-2",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4995581",
   "doi": "",
   "title": "[Thalidomide embryopathy with peculiar eye changes]",
   "authors": [
    "Welge-Lüssen L"
   ],
   "journal": "Klinische Monatsblatter fur Augenheilkunde",
   "year": "1971",
   "volume": "158",
   "pages": "372-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4926839",
   "doi": "",
   "title": "Congenital malformations: from Hippocrates to thalidomide",
   "authors": [
    "Persaud TV"
   ],
   "journal": "The West Indian medical journal",
   "year": "1970",
   "volume": "19",
   "pages": "240-6",
   "pubtypes": [
    "Historical Article"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5522156",
   "doi": "",
   "title": "Further observations on the thalidomide embryopathy in rabbits",
   "authors": [
    "Vickers TH",
    "Wrba H"
   ],
   "journal": "Experimentelle Pathologie",
   "year": "1970",
   "volume": "4",
   "pages": "81-97",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5430054",
   "doi": "",
   "title": "Malformation in the progeny of thalidomide-treated male rats",
   "authors": [
    "Husain SM",
    "Belanger-Barbeau M",
    "Pellerin M"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1970",
   "volume": "103",
   "pages": "163-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5502022",
   "doi": "10.1017/s1120962300025452",
   "title": "Thalidomide-embryopathy in twins: a collaborative study",
   "authors": [
    "Jörgensen G",
    "Lenz W",
    "Pfeiffer RA",
    "et al."
   ],
   "journal": "Acta geneticae medicae et gemellologiae",
   "year": "1970",
   "volume": "19",
   "pages": "205-10",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5429073",
   "doi": "",
   "title": "The alimentary tract malformations in the rabbit thalidomide embryopathy",
   "authors": [
    "Vickers TH"
   ],
   "journal": "British journal of experimental pathology",
   "year": "1970",
   "volume": "51",
   "pages": "286-97",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5802466",
   "doi": "",
   "title": "A six degree of freedom experimental limb for thalidomide children",
   "authors": [
    "Bousso D"
   ],
   "journal": "Biomedical engineering",
   "year": "1969",
   "volume": "4",
   "pages": "313-21",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5005593",
   "doi": "10.1002/dev.420020309",
   "title": "Motor skills of infant rhesus monkeys with thalidomide-induced forelimb malformations",
   "authors": [
    "Lindburg DG"
   ],
   "journal": "Developmental psychobiology",
   "year": "1969",
   "volume": "2",
   "pages": "184-90",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4317839",
   "doi": "",
   "title": "Nicotinamide deficiency and thalidomide: potential teratogenic disturbances in Long-Evans rats",
   "authors": [
    "Fratta ID"
   ],
   "journal": "Laboratory animal care",
   "year": "1969",
   "volume": "19",
   "pages": "727-32",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5375328",
   "doi": "",
   "title": "[The medical examination of children with malformations suspected to be due to thalidomide]",
   "authors": [
    "Winberg J"
   ],
   "journal": "Lakartidningen",
   "year": "1969",
   "volume": "66",
   "pages": "4539-47 passim",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5639104",
   "doi": "",
   "title": "A comparison of the teratogenic activity of thalidomide in rabbits and rats",
   "authors": [
    "Schumacher H",
    "Blake DA",
    "Gurian JM",
    "et al."
   ],
   "journal": "The Journal of pharmacology and experimental therapeutics",
   "year": "1968",
   "volume": "160",
   "pages": "189-200",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5246854",
   "doi": "",
   "title": "Clinical, orthodontic and radiological findings in the jaws and face of children with dysmelia associated with thalidomide-embryopathy",
   "authors": [
    "Stahl A"
   ],
   "journal": "International dental journal",
   "year": "1968",
   "volume": "18",
   "pages": "631-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5751867",
   "doi": "10.1007/BF02138700",
   "title": "Relationship between teratogeny and structure in the thalidomide field",
   "authors": [
    "Wuest HM",
    "Fox RR",
    "Crary DD"
   ],
   "journal": "Experientia",
   "year": "1968",
   "volume": "24",
   "pages": "993-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4973567",
   "doi": "10.1177/00220345680470053101",
   "title": "Skull and muzzle growth of a one-year-old baboon with thalidomide-induced malformations",
   "authors": [
    "Reed OM",
    "Hendrickx AG"
   ],
   "journal": "Journal of dental research",
   "year": "1968",
   "volume": "47",
   "pages": "838",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5689572",
   "doi": "",
   "title": "The cardiovascular malformations in the rabbit thalidomide embryopathy",
   "authors": [
    "Vickers TH"
   ],
   "journal": "British journal of experimental pathology",
   "year": "1968",
   "volume": "49",
   "pages": "179-96",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5690336",
   "doi": "",
   "title": "The susceptible period for thalidomide malformations in man and monkey",
   "authors": [
    "Lenz W"
   ],
   "journal": "German medical monthly",
   "year": "1968",
   "volume": "13",
   "pages": "197-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5691464",
   "doi": "",
   "title": "[Action of thalidomide on the rate of malformations in rats with preformed genetic damage caused by malachite green]",
   "authors": [
    "Werth G",
    "Hirth R"
   ],
   "journal": "Archiv fur Toxikologie",
   "year": "1968",
   "volume": "23",
   "pages": "104-11",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5240539",
   "doi": "",
   "title": "[Cephalometric findings in dysmelic children with symptoms of thalidomide embryopathy]",
   "authors": [
    "Stahl A"
   ],
   "journal": "Deutsche zahnarztliche Zeitschrift",
   "year": "1968",
   "volume": "23",
   "pages": "520-1",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5730684",
   "doi": "",
   "title": "[Congenital metabolic diseases--thalidomide embryopathies]",
   "authors": [
    "Kirchmair H"
   ],
   "journal": "Medizinische Monatsschrift",
   "year": "1968",
   "volume": "22",
   "pages": "114-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4972855",
   "doi": "",
   "title": "[Teratogenic action of thalidomide in superior vertebrates]",
   "authors": [
    "Salaün J"
   ],
   "journal": "L' Annee biologique",
   "year": "1968",
   "volume": "7",
   "pages": "307-26",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5716213",
   "doi": "",
   "title": "[Thalidomide embryopathy in Japan]",
   "authors": [
    "Kida M",
    "Lenz W"
   ],
   "journal": "Archiv fur Kinderheilkunde",
   "year": "1968",
   "volume": "177",
   "pages": "244-59",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6019648",
   "doi": "",
   "title": "The thalidomide embryopathy in hybrid rabbits",
   "authors": [
    "Vickers TH"
   ],
   "journal": "British journal of experimental pathology",
   "year": "1967",
   "volume": "48",
   "pages": "107-17",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6059519",
   "doi": "10.1038/215296a0",
   "title": "Toxicity and teratogenicity of optical isomers of thalidomide",
   "authors": [
    "Fabro S",
    "Smith RL",
    "Williams RT"
   ],
   "journal": "Nature",
   "year": "1967",
   "volume": "215",
   "pages": "296",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5595238",
   "doi": "",
   "title": "[Abnormalities of internal organs in thalidomide embryopathy. A contribution to the determination of the sensitivity phase in thalidomide administration during early pregnancy]",
   "authors": [
    "Kreipe U"
   ],
   "journal": "Archiv fur Kinderheilkunde",
   "year": "1967",
   "volume": "176",
   "pages": "33-61",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6064533",
   "doi": "10.1017/s1120962300013081",
   "title": "[Cleft lip and palate in thalidomide-induced embryopathies]",
   "authors": [
    "Immeyer F"
   ],
   "journal": "Acta geneticae medicae et gemellologiae",
   "year": "1967",
   "volume": "16",
   "pages": "244-74",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5598910",
   "doi": "",
   "title": "[Comparison of the teratogenic effect of chloridine and thalidomide on chick embryos]",
   "authors": [
    "Stanzhevskaia TI"
   ],
   "journal": "Farmakologiia i toksikologiia",
   "year": "1967",
   "volume": "30",
   "pages": "489-91",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5612751",
   "doi": "",
   "title": "[Congenital malformations in the past 10 years: incidence of aplasias of the extremities, with special reference to the so-called thalidomide embryopathy]",
   "authors": [
    "Torbidoni L",
    "Catania G",
    "Di Iulio P"
   ],
   "journal": "Annali della sanita pubblica",
   "year": "1967",
   "volume": "28",
   "pages": "1269-319",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5227327",
   "doi": "",
   "title": "[Dysplasia in the mouth, jaw and teeth in dysmelia. Contribution to the thalidomide-embryopathies]",
   "authors": [
    "Stahl A"
   ],
   "journal": "Deutsche zahnarztliche Zeitschrift",
   "year": "1967",
   "volume": "22",
   "pages": "356-67",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5627598",
   "doi": "",
   "title": "[Inhibition of the immune reaction by thalidomide and the results of this process on the theory of the teratogenous effect of this substance]",
   "authors": [
    "Hellmann K"
   ],
   "journal": "Wiener medizinische Wochenschrift (1946)",
   "year": "1967",
   "volume": "117",
   "pages": "415-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5593734",
   "doi": "",
   "title": "[Malformation and liver damage. On the necessary 2nd noxa in experimental thalidomide embryopathies]",
   "authors": [
    "Kirchmair H"
   ],
   "journal": "Wiener medizinische Wochenschrift (1946)",
   "year": "1967",
   "volume": "117",
   "pages": "418-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5180426",
   "doi": "",
   "title": "[Social rehabilitation of young thalidomide victims]",
   "authors": [
    "O'Brien M",
    "Owens M",
    "Ralph J"
   ],
   "journal": "L' Infirmiere canadienne",
   "year": "1967",
   "volume": "9",
   "pages": "34-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6070186",
   "doi": "",
   "title": "[The sensitivity period of thalidomide embryopathy in monkeys and humans]",
   "authors": [
    "Lenz W"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1967",
   "volume": "92",
   "pages": "2186-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5627596",
   "doi": "",
   "title": "[The so-called dysmelia syndrome (Thalidomide embryopathy) and its differential diagnosis]",
   "authors": [
    "Weicker H"
   ],
   "journal": "Wiener medizinische Wochenschrift (1946)",
   "year": "1967",
   "volume": "117",
   "pages": "387-90",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5971991",
   "doi": "",
   "title": "Early changes in limb buds of chick embryos after thalidomide treatment",
   "authors": [
    "Jurand A"
   ],
   "journal": "Journal of embryology and experimental morphology",
   "year": "1966",
   "volume": "16",
   "pages": "289-300",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4958479",
   "doi": "10.1111/j.1755-3768.1966.tb08048.x",
   "title": "Ocular malformations caused by thalidomide",
   "authors": [
    "Zetterström B"
   ],
   "journal": "Acta ophthalmologica",
   "year": "1966",
   "volume": "44",
   "pages": "391-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4958507",
   "doi": "",
   "title": "Teratogenic action of intermediate products of thalidomide synthesis on chick embryo",
   "authors": [
    "Aleksandrov PN",
    "Bogdanova VA",
    "Chernukh AM"
   ],
   "journal": "Federation proceedings. Translation supplement; selected translations from medical-related science",
   "year": "1966",
   "volume": "25",
   "pages": "910-2",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4959864",
   "doi": "",
   "title": "Teratogenic agents and thalidomide",
   "authors": [
    "Cullen JF"
   ],
   "journal": "Transactions of the ophthalmological societies of the United Kingdom",
   "year": "1966",
   "volume": "86",
   "pages": "101-13",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4957599",
   "doi": "",
   "title": "The rabbit thalidomide embryopathy",
   "authors": [
    "Pearn JH",
    "Vickers TH"
   ],
   "journal": "British journal of experimental pathology",
   "year": "1966",
   "volume": "47",
   "pages": "186-92",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "4958643",
   "doi": "10.1002/path.1700910227",
   "title": "The teratogenic activity of thalidomide in the rabbit",
   "authors": [
    "Fabro S",
    "Smith RL"
   ],
   "journal": "The Journal of pathology and bacteriology",
   "year": "1966",
   "volume": "91",
   "pages": "511-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6002005",
   "doi": "",
   "title": "[Cytogenetic and clinical studies in thalidomide damaged children with ear malformations]",
   "authors": [
    "Ahrens K"
   ],
   "journal": "Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde",
   "year": "1966",
   "volume": "186",
   "pages": "264-78",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5233658",
   "doi": "10.1007/BF02198463",
   "title": "[Dysgnathias in the deciduous dentition in dysmelia: contribution to thalidomide embryopathy]",
   "authors": [
    "Stahl A"
   ],
   "journal": "Fortschritte der Kieferorthopadie",
   "year": "1966",
   "volume": "27",
   "pages": "447-58",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5984889",
   "doi": "",
   "title": "[Reference to central nervous system damage within the context of thalidomide embryopathy. Pathological-anatomic, electroencephalographic and neurologic findings]",
   "authors": [
    "Horstmann W"
   ],
   "journal": "Zeitschrift fur Kinderheilkunde",
   "year": "1966",
   "volume": "96",
   "pages": "291-307",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5982666",
   "doi": "",
   "title": "[Thalidomide embryopathy in animal experiments. 3. Teratologic tests of thalidomide catabolic products]",
   "authors": [
    "Heine W"
   ],
   "journal": "Zeitschrift fur Kinderheilkunde",
   "year": "1966",
   "volume": "96",
   "pages": "141-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6010566",
   "doi": "",
   "title": "[Thalidomide embryopathy in animal experiments. II. Thalidomide blood level in experimental animals with normal and damaged liver]",
   "authors": [
    "Heine W",
    "Stüwe W"
   ],
   "journal": "Zeitschrift fur Kinderheilkunde",
   "year": "1966",
   "volume": "96",
   "pages": "14-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5181392",
   "doi": "",
   "title": "[Thalidomide victims in a rehabilitation center]",
   "authors": [
    "Soules BJ"
   ],
   "journal": "ha-Ahot be-Yisrael",
   "year": "1966",
   "volume": "12",
   "pages": "43-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "6004455",
   "doi": "",
   "title": "[The teratogenic effect of thalidomide in experiments on chick embryos]",
   "authors": [
    "Aleksandrov PN",
    "Bogdanova VA",
    "Chernukh AM"
   ],
   "journal": "Biulleten' eksperimental'noi biologii i meditsiny",
   "year": "1966",
   "volume": "61",
   "pages": "89-92",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5987924",
   "doi": "",
   "title": "[Toxic and teratogenic effects of thalidomide]",
   "authors": [
    "Arbab-Zadeh A"
   ],
   "journal": "Deutsche Zeitschrift fur die gesamte gerichtliche Medizin",
   "year": "1966",
   "volume": "57",
   "pages": "285-90",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5987158",
   "doi": "",
   "title": "[Triphalangia of the thumb as a manifestation of thalidomide embryopathy]",
   "authors": [
    "Rath F"
   ],
   "journal": "Wiener klinische Wochenschrift",
   "year": "1966",
   "volume": "78",
   "pages": "181-3",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14324233",
   "doi": "10.1139/y65-008",
   "title": "AN ATTEMPTED REVERSAL OF THALIDOMIDE EMBRYOPATHY IN THE RAT BY GLUTAMINE",
   "authors": [
    "MCCOLL JD",
    "GLOBUS M",
    "ROBINSON S"
   ],
   "journal": "Canadian journal of physiology and pharmacology",
   "year": "1965",
   "volume": "43",
   "pages": "69-73",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14270212",
   "doi": "",
   "title": "CONGENITAL MALFORMATIONS IN A THALIDOMIDE BABY: A POSTMORTEM ANATOMICAL STUDY",
   "authors": [
    "HAGEN EO"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1965",
   "volume": "92",
   "pages": "283-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14287841",
   "doi": "10.2105/ajph.55.5.703",
   "title": "PROBLEMS RAISED FOR THE FDA BY THE OCCURRENCE OF THALIDOMIDE EMBRYOPATHY IN GERMANY, 1960-1961",
   "authors": [
    "KELSEY FO"
   ],
   "journal": "American journal of public health and the nation's health",
   "year": "1965",
   "volume": "55",
   "pages": "703-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "19994415",
   "doi": "10.1177/003591576505800710",
   "title": "Principles of Teratogenesis: Mode of Action of Thalidomide",
   "authors": [
    "Woollam DH"
   ],
   "journal": "Proceedings of the Royal Society of Medicine",
   "year": "1965",
   "volume": "58",
   "pages": "497-501",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14278616",
   "doi": "10.1177/028418516500300205",
   "title": "RADIOGRAPHIC STUDIES OF THALIDOMIDE-INDUCED MALFORMATIONS IN MICE",
   "authors": [
    "GATZEK H",
    "DIPAOLO JA"
   ],
   "journal": "Acta radiologica: diagnosis",
   "year": "1965",
   "volume": "3",
   "pages": "145-50",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14329487",
   "doi": "",
   "title": "SKELETAL MALFORMATIONS IN THE HOLTZMAN RAT EMBRYO FOLLOWING THE ADMINISTRATION OF THALIDOMIDE",
   "authors": [
    "DWORNIK JJ",
    "MOORE KL"
   ],
   "journal": "Journal of embryology and experimental morphology",
   "year": "1965",
   "volume": "13",
   "pages": "181-93",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5866808",
   "doi": "10.1016/0041-008x(65)90126-2",
   "title": "Susceptibility of certain inbred strains of hamsters to teratogenic effects of thalidomide",
   "authors": [
    "Homburger F",
    "Chaube S",
    "Eppenberger M",
    "et al."
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "1965",
   "volume": "7",
   "pages": "686-93",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14298018",
   "doi": "10.1016/0041-008x(65)90095-5",
   "title": "TERATOGENIC EFFECTS OF THALIDOMIDE IN RABBITS, RATS, HAMSTERS, AND MICE",
   "authors": [
    "FRATTA ID",
    "SIGG EB",
    "MAIORANA K"
   ],
   "journal": "Toxicology and applied pharmacology",
   "year": "1965",
   "volume": "7",
   "pages": "268-86",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14282853",
   "doi": "10.1136/adc.40.210.154",
   "title": "THALIDOMIDE EMBRYOPATHY AND LIMB DEFECTS; ESPERIENCES IN HABILITATION OF CHILDREN WITH ECTROMELIAS",
   "authors": [
    "MAIER WA"
   ],
   "journal": "Archives of disease in childhood",
   "year": "1965",
   "volume": "40",
   "pages": "154-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14266563",
   "doi": "",
   "title": "THE MANAGEMENT OF UPPER LIMB DEFICIENCIES IN THE THALIDOMIDE-TYPE SYNDROME",
   "authors": [
    "LAMB DW",
    "SIMPSON DC",
    "SCHUTT WH",
    "et al."
   ],
   "journal": "Journal of the Royal College of Surgeons of Edinburgh",
   "year": "1965",
   "volume": "10",
   "pages": "102-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5889911",
   "doi": "10.1136/bmj.2.5469.1064-b",
   "title": "Teratogenetic properties of thalidomide",
   "authors": [
    "James WH"
   ],
   "journal": "British medical journal",
   "year": "1965",
   "volume": "2",
   "pages": "1064",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5868263",
   "doi": "10.1007/BF02144076",
   "title": "Thalidomide malformations and genetic background in the rabbit",
   "authors": [
    "Sawin PB",
    "Crary D",
    "Fox RR",
    "et al."
   ],
   "journal": "Experientia",
   "year": "1965",
   "volume": "21",
   "pages": "672-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5863780",
   "doi": "10.3382/ps.0441583",
   "title": "Thalidomide teratogenesis in the developing chick embryo and its relationship to vitamin metabolism",
   "authors": [
    "Naber EC",
    "Largent EJ"
   ],
   "journal": "Poultry science",
   "year": "1965",
   "volume": "44",
   "pages": "1583-91",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14271245",
   "doi": "",
   "title": "[ABNORMALITIES OF THE INTERNAL AND MIDDLE EAR AS A SEQUEL TO THALIDOMIDE EMBRYOPATHY--RESULTS OF TOMOGRAPHIC EXAMINATIONS OF THE EAR]",
   "authors": [
    "TERRAHE K"
   ],
   "journal": "Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin",
   "year": "1965",
   "volume": "102",
   "pages": "14-29",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5882447",
   "doi": "",
   "title": "[Malformations caused by thalidomide in ORL. Clinical contribution]",
   "authors": [
    "Cortesina G"
   ],
   "journal": "Minerva otorinolaringologica",
   "year": "1965",
   "volume": "15",
   "pages": "148-52",
   "pubtypes": [
    "Case Reports"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5864769",
   "doi": "",
   "title": "[On the problems of thalidomide embryopathy]",
   "authors": [
    "Krückemeyer K"
   ],
   "journal": "Die Medizinische Welt",
   "year": "1965",
   "volume": "41",
   "pages": "2318-20",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14305250",
   "doi": "",
   "title": "[ROENTGENOLOGIC CHANGES IN RABBIT THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "ERFURTH F"
   ],
   "journal": "Zeitschrift fur Kinderheilkunde",
   "year": "1965",
   "volume": "92",
   "pages": "90-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5843508",
   "doi": "10.1055/s-0028-1113502",
   "title": "[Thalidomide embryopathy. V. Kidney malformations]",
   "authors": [
    "Hauke H",
    "Weicker H"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1965",
   "volume": "90",
   "pages": "2200-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5215699",
   "doi": "",
   "title": "[Thalidomide-embryopathies and their effect on dentition]",
   "authors": [
    "Schübel F",
    "Partsch CJ"
   ],
   "journal": "Deutsche zahnarztliche Zeitschrift",
   "year": "1965",
   "volume": "20",
   "pages": "1278-83",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5891470",
   "doi": "",
   "title": "[Thalidomide: embryopathies in dogs]",
   "authors": [
    "Delatour P",
    "Dams R",
    "Favre-Tissot M"
   ],
   "journal": "Therapie",
   "year": "1965",
   "volume": "20",
   "pages": "573-89",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5868429",
   "doi": "10.1007/BF00338341",
   "title": "[The sensitive phase in thalidomide embryopathy]",
   "authors": [
    "Nowack E"
   ],
   "journal": "Humangenetik",
   "year": "1965",
   "volume": "1",
   "pages": "516-36",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "5876387",
   "doi": "",
   "title": "[The teratogenic effect of intermediate products of thalidomide synthesis upon the chick embryo]",
   "authors": [
    "Aleksandrov PN",
    "Bogdanova VA",
    "Chernukh AM"
   ],
   "journal": "Farmakologiia i toksikologiia",
   "year": "1965",
   "volume": "28",
   "pages": "744-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14118500",
   "doi": "10.1016/0002-8703(64)90383-7",
   "title": "CONGENITAL MALFORMATIONS ASSOCIATED WITH THALIDOMIDE AND THEIR MANAGEMENT",
   "authors": [
    "MARTIN JK"
   ],
   "journal": "American heart journal",
   "year": "1964",
   "volume": "67",
   "pages": "284-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14149012",
   "doi": "10.1016/s0022-3476(64)80626-0",
   "title": "DRUG TESTING IN ANIMALS FOR TERATOGENIC EFFECTS. THALIDOMIDE IN THE PREGNANT RAT",
   "authors": [
    "BRENT RL"
   ],
   "journal": "The Journal of pediatrics",
   "year": "1964",
   "volume": "64",
   "pages": "762-70",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14074477",
   "doi": "10.1016/s0140-6736(64)92219-6",
   "title": "EARLY TREATMENT OF CONGENITAL BONE DEFECTS OF THE EXTREMITIES: AFTERMATH OF THALIDOMIDE DISASTER",
   "authors": [
    "SULAMAA M",
    "RYOEPPY S"
   ],
   "journal": "Lancet (London, England)",
   "year": "1964",
   "volume": "1",
   "pages": "130-2",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14158501",
   "doi": "10.1002/ar.1091490113",
   "title": "MALFORMATIONS INDUCED IN THE MOUSE BY THALIDOMIDE",
   "authors": [
    "DIPAOLO JA",
    "GATZEK H",
    "PICKREN J"
   ],
   "journal": "The Anatomical record",
   "year": "1964",
   "volume": "149",
   "pages": "149-55",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14105795",
   "doi": "",
   "title": "PROBLEMS RAISED FOR THE FDA BY THE OCCURRENCE OF THALIDOMIDE EMBRYOPATHY IN GERMANY 1960-1961",
   "authors": [
    "KELSEY FO"
   ],
   "journal": "The South Dakota journal of medicine and pharmacy",
   "year": "1964",
   "volume": "17",
   "pages": "36-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14107977",
   "doi": "10.1016/s0140-6736(64)91560-0",
   "title": "TERATOGENIC ACTION OF THALIDOMIDE",
   "authors": [
    "FELISATI D"
   ],
   "journal": "Lancet (London, England)",
   "year": "1964",
   "volume": "1",
   "pages": "724-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14206053",
   "doi": "10.1016/0024-3205(64)90109-2",
   "title": "TERATOGENIC ACTIVITY OF THALIDOMIDE AND RELATED COMPOUNDS",
   "authors": [
    "FABRO S",
    "SCHUMACHER H",
    "SMITH RL",
    "et al."
   ],
   "journal": "Life sciences (1962)",
   "year": "1964",
   "volume": "3",
   "pages": "987-92",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14171814",
   "doi": "10.1056/NEJM196408272710904",
   "title": "THALIDOMIDE EMBRYOPATHY IN HYBRID RABBITS",
   "authors": [
    "INGALLS TH",
    "CURLEY FJ",
    "ZAPPASODI P"
   ],
   "journal": "The New England journal of medicine",
   "year": "1964",
   "volume": "271",
   "pages": "441-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14209043",
   "doi": "",
   "title": "THE USE OF THALIDOMIDE AS TERATOGENIC AGENT IN RABBITS",
   "authors": [
    "DEKKER A",
    "MEHRIZI A"
   ],
   "journal": "Bulletin of the Johns Hopkins Hospital",
   "year": "1964",
   "volume": "115",
   "pages": "223-30",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14117097",
   "doi": "10.1055/s-0028-1111031",
   "title": "[DRUG USE DURING PREGNANCY AFTER DISCOVERY OF THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "MAUSS HJ"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1964",
   "volume": "89",
   "pages": "380-3",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14137030",
   "doi": "",
   "title": "[EAR DEFORMITIES IN THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "PARTSCH CJ"
   ],
   "journal": "Munchener medizinische Wochenschrift (1950)",
   "year": "1964",
   "volume": "106",
   "pages": "290-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14233598",
   "doi": "",
   "title": "[EAR MALFORMATIONS IN THE FRAMEWORK OF THALIDOMIDE EMBRYOPATHY. (BASED ON A SURVEY OF 70 INFANTS BORN DURING 1959-1962)]",
   "authors": [
    "KLEINSASSER O",
    "SCHLOTHANE R"
   ],
   "journal": "Zeitschrift fur Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete",
   "year": "1964",
   "volume": "43",
   "pages": "344-67",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14275918",
   "doi": "",
   "title": "[FETAL MALFORMATIONS PRODUCED BY THALIDOMIDE IN THE MOUSE]",
   "authors": [
    "SILVESTRINI B",
    "GARAU A"
   ],
   "journal": "Bollettino chimico farmaceutico",
   "year": "1964",
   "volume": "103",
   "pages": "804-14",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14266035",
   "doi": "",
   "title": "[INDUCTION OF FETAL MALFORMATIONS IN RABBITS WITH THALIDOMIDE]",
   "authors": [
    "LOOSLI B"
   ],
   "journal": "Pathologia et microbiologia",
   "year": "1964",
   "volume": "27",
   "pages": "1003-11",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14260522",
   "doi": "",
   "title": "[OCULOMOTOR PARALYSIS IN THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "SCHMIDT JG"
   ],
   "journal": "Bericht uber die Zusammenkunft. Deutsche Ophthalmologische Gesellschaft",
   "year": "1964",
   "volume": "65",
   "pages": "215-20",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14334486",
   "doi": "",
   "title": "[SIMILARITIES AND PECULIARITIES OF FANCONI'S ANEMIA AND THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "WEICKER H"
   ],
   "journal": "Schweizerische medizinische Wochenschrift",
   "year": "1964",
   "volume": "94",
   "pages": "1319-21",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14196316",
   "doi": "10.3950/jibiinkoka.67.5_718",
   "title": "[THALIDOMIDE AND EAR-MALFORMATION]",
   "authors": [
    "SUZUKI Y",
    "HAYASAKI H",
    "SUGIYAMA S",
    "et al."
   ],
   "journal": "Nihon Jibiinkoka Gakkai kaiho",
   "year": "1964",
   "volume": "67",
   "pages": "718-29",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14333485",
   "doi": "",
   "title": "[THALIDOMIDE EMBRYOPATHY IN ANIMAL EXPERIMENT. REPRODUCTION OF THE THALIDOMIDE EMBRYOPATHY IN A TERATOLOGIC EXPERIMENT IN RABBITS WITH TRANSIENT LIVER DAMAGE]",
   "authors": [
    "HEINE W",
    "KIRCHMAIR H",
    "FIEDLER M",
    "et al."
   ],
   "journal": "Zeitschrift fur Kinderheilkunde",
   "year": "1964",
   "volume": "91",
   "pages": "213-21",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14236990",
   "doi": "10.1007/BF01487793",
   "title": "[THALIDOMIDE EMBRYOPATHY IN RABBITS FOLLOWING TRANSIENT LIVER DAMAGE IN THE MOTHER BY CARBON TETRACHLORIDE]",
   "authors": [
    "HEINE W",
    "KIRCHMAIR H",
    "FIEDLER M",
    "et al."
   ],
   "journal": "Klinische Wochenschrift",
   "year": "1964",
   "volume": "42",
   "pages": "592",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14160749",
   "doi": "",
   "title": "[THALIDOMIDE TERATOGENESIS IN CHICKS]",
   "authors": [
    "SEVASTIKOGLOU JA"
   ],
   "journal": "Nordisk medicin",
   "year": "1964",
   "volume": "72",
   "pages": "853-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14336557",
   "doi": "",
   "title": "[THE CONTRIBUTION OF EXPERIMENTAL ANIMAL STUDIES TO THE CLARIFICATION OF THE QUESTION OF RESPONSIBILITY IN THE CASE OF THALIDOMIDE (CONTERGAN) DAMAGE]",
   "authors": [
    "ARBAB-ZADEH A"
   ],
   "journal": "Die Medizinische Welt",
   "year": "1964",
   "volume": "52",
   "pages": "2797-802",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14028006",
   "doi": "",
   "title": "Congenital malformation in strain A mice. Its experimental production by thalidomide",
   "authors": [
    "DIPAOLO JA"
   ],
   "journal": "JAMA",
   "year": "1963",
   "volume": "183",
   "pages": "139-41",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14088464",
   "doi": "",
   "title": "DRUG EMBRYOPATHY: THE THALIDOMIDE STORY",
   "authors": [
    "KELSEY FO"
   ],
   "journal": "Maryland state medical journal",
   "year": "1963",
   "volume": "12",
   "pages": "594-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20327525",
   "doi": "",
   "title": "Habilitation of Patients with Congenital Malformations Associated with Thalidomide: Medical-Social Aspects",
   "authors": [
    "Armstrong KS"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1963",
   "volume": "88",
   "pages": "980-1",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20327524",
   "doi": "",
   "title": "Habilitation of Patients with Congenital Malformations Associated with Thalidomide: Pediatric Aspects",
   "authors": [
    "Martin JK",
    "Rathbun JC"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1963",
   "volume": "88",
   "pages": "959-62",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13947980",
   "doi": "",
   "title": "Habilitation of patients with congenital malformations associated with thalidomide: prosthetic aspects",
   "authors": [
    "GILPIN RE"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1963",
   "volume": "88",
   "pages": "973-9",
   "pubtypes": [],
   "codes": [
    "1027",
    "2879",
    "thal"
   ],
   "topics": [
    "prosthetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13928763",
   "doi": "",
   "title": "Habilitation of patients with congenital malformations associated with thalidomide: psychiatric and psychological aspects",
   "authors": [
    "LAZURE D"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1963",
   "volume": "88",
   "pages": "962-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13952105",
   "doi": "",
   "title": "Habilitation of patients with congenital malformations associated with thalidomide: surgery of limb defects",
   "authors": [
    "HALL JE"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1963",
   "volume": "88",
   "pages": "964-72",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "prosthetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13932175",
   "doi": "",
   "title": "Phocomelia. A case report without thalidomide ingestion",
   "authors": [
    "MCLELLAND R"
   ],
   "journal": "Virginia medical monthly",
   "year": "1963",
   "volume": "90",
   "pages": "238-9",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14131811",
   "doi": "10.1111/j.1600-0773.1963.tb01736.x",
   "title": "THE TERATOGENIC EFFECTS OF THALIDOMIDE, IMIPRAMINE HC1 AND IMIPRAMINE-N-OXIDE HC1 ON WHITE DANISH RABBITS",
   "authors": [
    "LARSEN V"
   ],
   "journal": "Acta pharmacologica et toxicologica",
   "year": "1963",
   "volume": "20",
   "pages": "186-200",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14010466",
   "doi": "10.1016/s0140-6736(63)91486-7",
   "title": "Teratogenic effects of thalidomide and related substances",
   "authors": [
    "WILLIAMS RT"
   ],
   "journal": "Lancet (London, England)",
   "year": "1963",
   "volume": "1",
   "pages": "723-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14014741",
   "doi": "10.1016/s0140-6736(63)91346-1",
   "title": "Teratogenic effects of thalidomide and related substances",
   "authors": [
    "BOYLEN JB",
    "HORNE HH",
    "JOHNSON WJ"
   ],
   "journal": "Lancet (London, England)",
   "year": "1963",
   "volume": "1",
   "pages": "552",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13992358",
   "doi": "",
   "title": "Thalidomide embryopathy",
   "authors": [
    "SCHONENBERG H"
   ],
   "journal": "Annales paediatrici. International review of pediatrics",
   "year": "1963",
   "volume": "200",
   "pages": "60-75",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14024392",
   "doi": "10.1016/s0009-9260(63)80077-x",
   "title": "Thalidomide induced malformations--a radiological survey",
   "authors": [
    "CUTHBERT R",
    "SPEIRS AL"
   ],
   "journal": "Clinical radiology",
   "year": "1963",
   "volume": "14",
   "pages": "163-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13989607",
   "doi": "10.1016/s0140-6736(63)92129-9",
   "title": "The incidence of limb and ear defects since the withdrawal of thalidomide",
   "authors": [
    "SMITHELLS RW"
   ],
   "journal": "Lancet (London, England)",
   "year": "1963",
   "volume": "1",
   "pages": "1095-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14099577",
   "doi": "",
   "title": "[1ST CASE OF THALIDOMIDE EMBRYOPATHY STUDIED IN FRANCE]",
   "authors": [
    "RAVAILLE G",
    "METZ J",
    "MAUER ML"
   ],
   "journal": "Archives francaises de pediatrie",
   "year": "1963",
   "volume": "20",
   "pages": "1242-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13960403",
   "doi": "",
   "title": "[2 cases of phocomelia (caused by thalidomide?) observed at the Ospedale Maria Vittoria di Torino]",
   "authors": [
    "GANDOLFO CARAMELLO MT"
   ],
   "journal": "Minerva medica",
   "year": "1963",
   "volume": "54",
   "pages": "567-9",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14053133",
   "doi": "",
   "title": "[ANATOMOCLINICAL STUDY OF 19 CASES OF EMBRYOPATHY CAUSED BY THALIDOMIDE]",
   "authors": [
    "MATTURRI L",
    "NODARI R"
   ],
   "journal": "Folia hereditaria et pathologica",
   "year": "1963",
   "volume": "12",
   "pages": "267-78",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14074800",
   "doi": "",
   "title": "[CONGENITAL MALFORMATIONS AND THALIDOMIDE]",
   "authors": [
    "VIZZONI L",
    "DINELLI P"
   ],
   "journal": "Rivista di clinica pediatrica",
   "year": "1963",
   "volume": "71",
   "pages": "201-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14051513",
   "doi": "",
   "title": "[CONTINUOUS RISE IN THE INCIDENCE OF PHOCOMELIA IN NEWBORN INFANTS IN WESTERN EUROPE AND ITS RELATION TO THALIDOMIDE ADMINISTRATION. CURRENT STATUS OF THE PROBLEM]",
   "authors": [
    "VOTAVA Z"
   ],
   "journal": "Casopis lekaru ceskych",
   "year": "1963",
   "volume": "102",
   "pages": "561-4",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13961192",
   "doi": "",
   "title": "[Chromosomal studies on so-called thalidomide embryopathy]",
   "authors": [
    "HIRSCH M"
   ],
   "journal": "Medizinische Klinik",
   "year": "1963",
   "volume": "58",
   "pages": "397-400",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "genetics"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13989006",
   "doi": "",
   "title": "[Comments on the aetiology of the dysmelia syndrome]",
   "authors": [
    "SIEVERS G"
   ],
   "journal": "Methods of information in medicine",
   "year": "1963",
   "volume": "2",
   "pages": "52-8",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14076177",
   "doi": "",
   "title": "[EFFECT OF DRUGS ON THE DEVELOPMENT OF THE FETUS WITH REFERENCE TO THE TERATOGENIC EFFECT OF THALIDOMIDE]",
   "authors": [
    "VOTAVA Z"
   ],
   "journal": "Ceskoslovenska farmacie",
   "year": "1963",
   "volume": "12",
   "pages": "254-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14033715",
   "doi": "",
   "title": "[Embryopathy due to thalidomide]",
   "authors": [
    "KNAPP K",
    "LENZ W"
   ],
   "journal": "Revista espanola de pediatria",
   "year": "1963",
   "volume": "19",
   "pages": "39-45",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14000057",
   "doi": "",
   "title": "[General and special problems concerning the analysis of causes of malformations, especially thalidomide and aminopterin damages]",
   "authors": [
    "WERTHEMANN A"
   ],
   "journal": "Schweizerische medizinische Wochenschrift",
   "year": "1963",
   "volume": "93",
   "pages": "223-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14089608",
   "doi": "",
   "title": "[HOW TO EXPLAIN THE TERATOGENIC ACTION OF THALIDOMIDE]",
   "authors": [
    "ANDRIEU R"
   ],
   "journal": "Clinique (Paris, France)",
   "year": "1963",
   "volume": "58",
   "pages": "509-11",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13991256",
   "doi": "",
   "title": "[Malformations of extremities obtained in the chick embryo after treatment by thalidomide]",
   "authors": [
    "SALZGEBER B",
    "SALAUN J"
   ],
   "journal": "Comptes rendus des seances de la Societe de biologie et de ses filiales",
   "year": "1963",
   "volume": "157",
   "pages": "2719-22",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14117878",
   "doi": "",
   "title": "[ON A CASE OF THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "BALDRIGHI M",
    "NODARI R"
   ],
   "journal": "Il Fracastoro",
   "year": "1963",
   "volume": "56",
   "pages": "414-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14117008",
   "doi": "",
   "title": "[ON THE FORMAL GENESIS OF EAR ABNORMALITIES IN THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "PARTSCH CJ",
    "MAURER H"
   ],
   "journal": "Archiv fur Ohren-, Nasen- und Kehlkopfheilkunde",
   "year": "1963",
   "volume": "182",
   "pages": "594-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14091277",
   "doi": "",
   "title": "[ON THE TERATOGENICITY OF THALIDOMIDE, WITH SPECIAL REFERENCE TO MALFORMATIONS OF THE CEPHALIC PORTION OF THE BODY]",
   "authors": [
    "FELISATI D"
   ],
   "journal": "Annali di laringologia, otologia, rinologia, faringologia",
   "year": "1963",
   "volume": "62",
   "pages": "397-415",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14047686",
   "doi": "10.1055/s-0028-1112290",
   "title": "[PERSISTENT TRUNCUS ARTERIOSUS COMMUNIS IN SO-CALLED THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "SCHUMACHER H",
    "ODUNJO F"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1963",
   "volume": "88",
   "pages": "1743-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14080645",
   "doi": "",
   "title": "[PHOCOMELIA SYNDROME CAUSED BY THALIDOMIDE]",
   "authors": [
    "PINCHERLE M",
    "GAROFANO I"
   ],
   "journal": "Chirurgia italiana",
   "year": "1963",
   "volume": "15",
   "pages": "168-77",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14033716",
   "doi": "",
   "title": "[Studies on Thalidomide as a cause of congenital malformations]",
   "authors": [
    "KNAPP K",
    "LENZ W"
   ],
   "journal": "Methods of information in medicine",
   "year": "1963",
   "volume": "2",
   "pages": "49-51",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14048649",
   "doi": "",
   "title": "[TERATOGENIC EFFECT OF ORGANIC COMPOUNDS. III. FURTHER THALIDOMIDE EXPERIMENTS]",
   "authors": [
    "RIEMSCHNEIDER R",
    "BROCKMEYER K"
   ],
   "journal": "Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete",
   "year": "1963",
   "volume": "18",
   "pages": "587-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14111082",
   "doi": "",
   "title": "[THALIDOMIDE EMBRYOPATHIES IN MILANO AND SUBURBS. ANATOMO-CLINICAL STUDY]",
   "authors": [
    "MATTURRI L",
    "NODARI R"
   ],
   "journal": "Minerva pediatrica",
   "year": "1963",
   "volume": "15",
   "pages": "1303-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14111077",
   "doi": "",
   "title": "[THALIDOMIDE EMBRYOPATHY IN ITALY]",
   "authors": [
    "TORRICELLI C"
   ],
   "journal": "Minerva pediatrica",
   "year": "1963",
   "volume": "15",
   "pages": "1296-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14121994",
   "doi": "",
   "title": "[THALIDOMIDE EMBRYOPATHY. SURVEY AND PATHOGENIC MECHANISM]",
   "authors": [
    "VOGL A"
   ],
   "journal": "Arztliche Forschung",
   "year": "1963",
   "volume": "17",
   "pages": "640-3",
   "pubtypes": [
    "Review"
   ],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical",
    "review"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14047005",
   "doi": "",
   "title": "[THALIDOMIDE EMBRYOPATHY]",
   "authors": [
    "KASS E"
   ],
   "journal": "Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke",
   "year": "1963",
   "volume": "83",
   "pages": "1402-3",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14112689",
   "doi": "",
   "title": "[TOXIC AND TERATOGENIC EFFECTS OF THALIDOMIDE ON A RABBIT FETUS]",
   "authors": [
    "FELISATI D",
    "NODARI R"
   ],
   "journal": "Schweizerische medizinische Wochenschrift",
   "year": "1963",
   "volume": "93",
   "pages": "1559-62",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14103451",
   "doi": "10.1055/s-0028-1112359",
   "title": "[TWINS WITH MALFORMATIONS OF THE EXTREMITIES. THALIDOMIDE EMBRYOPATHY. 3]",
   "authors": [
    "PFEIFFER RA",
    "WEICKER H",
    "BACHMANN KD",
    "et al."
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1963",
   "volume": "88",
   "pages": "2293-302",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14111925",
   "doi": "10.1055/s-0028-1112365",
   "title": "[TWINS WITH MALFORMATIONS OF THE EXTREMITIES. THALIDOMIDE EMBRYOPATHY. III]",
   "authors": [
    "PFEIFFER RA",
    "WEICKER H",
    "BACHMANN KD",
    "et al."
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1963",
   "volume": "88",
   "pages": "2347-54",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13991257",
   "doi": "",
   "title": "[Teratogenic action of thalidomide on the chick embryo, at different stages of development]",
   "authors": [
    "SALZGEBER B",
    "SALAUN J"
   ],
   "journal": "Comptes rendus hebdomadaires des seances de l'Academie des sciences",
   "year": "1963",
   "volume": "257",
   "pages": "273-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13999526",
   "doi": "",
   "title": "[Thalidomide embryopathy]",
   "authors": [
    "WEICKER H"
   ],
   "journal": "Annales paediatrici. International review of pediatrics",
   "year": "1963",
   "volume": "200",
   "pages": "134-9",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13919869",
   "doi": "",
   "title": "A study of the German outbreak of phocomelia. The thalidomide syndrome",
   "authors": [
    "TAUSSIG HB"
   ],
   "journal": "JAMA",
   "year": "1962",
   "volume": "180",
   "pages": "1106-14",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13981529",
   "doi": "",
   "title": "Congenital malformations associated with a single umbilical artery and probable use of thalidomide",
   "authors": [
    "REISNER SH",
    "PALTI ZK"
   ],
   "journal": "Israel medical journal",
   "year": "1962",
   "volume": "21",
   "pages": "260-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14451359",
   "doi": "10.1080/19485565.1962.9987510",
   "title": "Congenital malformations attributed to sleeping pill (Thalidomide)",
   "authors": [
    "JARVIK LF"
   ],
   "journal": "Eugenics quarterly",
   "year": "1962",
   "volume": "9",
   "pages": "95-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20327332",
   "doi": "",
   "title": "Drug-Induced (Thalidomide) Malformations",
   "authors": [
    "Ing GM",
    "Olman CL",
    "Oyd JR"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1962",
   "volume": "87",
   "pages": "1259-62",
   "pubtypes": [],
   "codes": [
    "1027",
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14463369",
   "doi": "10.1136/bmj.2.5296.16",
   "title": "Incidence of malformations since the introduction of thalidomide",
   "authors": [
    "LECK IM",
    "MILLAR EL"
   ],
   "journal": "British medical journal",
   "year": "1962",
   "volume": "2",
   "pages": "16-20",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13929004",
   "doi": "10.1136/bmj.2.5317.1447",
   "title": "Phocomelia and internal defects due to thalidomide",
   "authors": [
    "LECUTIER MA"
   ],
   "journal": "British medical journal",
   "year": "1962",
   "volume": "2",
   "pages": "1447-8",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13919870",
   "doi": "10.1016/0002-9378(62)90079-0",
   "title": "Phocomelia and thalidomide",
   "authors": [
    "TAUSSIG HB"
   ],
   "journal": "American journal of obstetrics and gynecology",
   "year": "1962",
   "volume": "84",
   "pages": "979",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13936746",
   "doi": "",
   "title": "Teratogenic effects in rats of growth inhibiting chemicals, including studies on thalidomide",
   "authors": [
    "MURPHY ML"
   ],
   "journal": "Clinical proceedings - Children's Hospital of the District of Columbia",
   "year": "1962",
   "volume": "18",
   "pages": "307-22",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20327052",
   "doi": "",
   "title": "Thalidomide and Congenital Malformations",
   "authors": [],
   "journal": "Canadian Medical Association journal",
   "year": "1962",
   "volume": "86",
   "pages": "462-3",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "20327094",
   "doi": "",
   "title": "Thalidomide and Congenital Malformations",
   "authors": [
    "Munn JD"
   ],
   "journal": "Canadian Medical Association journal",
   "year": "1962",
   "volume": "86",
   "pages": "665",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14473931",
   "doi": "10.1016/s0140-6736(62)90462-2",
   "title": "Thalidomide and limb deformities",
   "authors": [
    "MILLEN JW"
   ],
   "journal": "Lancet (London, England)",
   "year": "1962",
   "volume": "2",
   "pages": "599-600",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13914462",
   "doi": "10.1016/s0140-6736(62)92367-x",
   "title": "Thalidomide and malformations in Liverpool",
   "authors": [
    "SMITHELLS RW"
   ],
   "journal": "Lancet (London, England)",
   "year": "1962",
   "volume": "1",
   "pages": "1270-3",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13993505",
   "doi": "",
   "title": "Thalidomide and phocomelia",
   "authors": [
    "TAUSSIG HB"
   ],
   "journal": "Pediatrics",
   "year": "1962",
   "volume": "30",
   "pages": "654-9",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13898662",
   "doi": "10.1136/bmj.2.5305.647",
   "title": "Thalidomide babies: management of limb defects",
   "authors": [
    "GILLIS L"
   ],
   "journal": "British medical journal",
   "year": "1962",
   "volume": "2",
   "pages": "647-51",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14008289",
   "doi": "10.1136/bmj.2.5299.236",
   "title": "Thalidomide disaster considered as an experiment in mammalian teratology",
   "authors": [
    "WOOLLAM DH"
   ],
   "journal": "British medical journal",
   "year": "1962",
   "volume": "2",
   "pages": "236-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14464040",
   "doi": "",
   "title": "Thalidomide embryopathy",
   "authors": [
    "LENZ W",
    "KNAPP K"
   ],
   "journal": "Archives of environmental health",
   "year": "1962",
   "volume": "5",
   "pages": "100-5",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13934699",
   "doi": "10.1056/NEJM196212062672305",
   "title": "The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies",
   "authors": [
    "MELLIN GW",
    "KATZENSTEIN M"
   ],
   "journal": "The New England journal of medicine",
   "year": "1962",
   "volume": "267",
   "pages": "1184-92 contd",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13934700",
   "doi": "10.1056/NEJM196212132672407",
   "title": "The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies",
   "authors": [
    "MELLIN GW",
    "KATZENSTEIN M"
   ],
   "journal": "The New England journal of medicine",
   "year": "1962",
   "volume": "267",
   "pages": "1238-44 concl",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13995093",
   "doi": "",
   "title": "[A case of phocomelia of the upper limbs probably induced by thalidomide]",
   "authors": [
    "UCHINO S",
    "NANJYO N",
    "UCHINO H",
    "et al."
   ],
   "journal": "Journal of the Japanese Obstetrical & Gynecological Society",
   "year": "1962",
   "volume": "14",
   "pages": "968-74",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13941471",
   "doi": "",
   "title": "[Abnormalities caused by Contergan (thalidomide, N-phtalimido-glutarimide) in Drosophila melanogaster]",
   "authors": [
    "PARKASH O"
   ],
   "journal": "Wiener klinische Wochenschrift",
   "year": "1962",
   "volume": "74",
   "pages": "920-1",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14018561",
   "doi": "",
   "title": "[Considerations on 2 cases of phocomelia. Embryopathy caused by thalidomide]",
   "authors": [
    "CARBONELL JUANICO M",
    "BALANZO CABOT E",
    "TRIAS DE BES JM"
   ],
   "journal": "Revista espanola de pediatria",
   "year": "1962",
   "volume": "18",
   "pages": "687-705",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13946309",
   "doi": "",
   "title": "[Description of a case of phocomelia. Its etiological relation to thalidomide]",
   "authors": [
    "GAMALERO PC",
    "CANESTRI G"
   ],
   "journal": "Minerva pediatrica",
   "year": "1962",
   "volume": "14",
   "pages": "1547-51",
   "pubtypes": [],
   "codes": [
    "2879",
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13874558",
   "doi": "",
   "title": "[Embryopathies caused by thalidomide]",
   "authors": [
    "BUKIET V"
   ],
   "journal": "Concours medical",
   "year": "1962",
   "volume": "84",
   "pages": "3999-4000",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13948223",
   "doi": "",
   "title": "[Observatios on the teratogenic repercussions of thalidomide in the mouse and rabbit]",
   "authors": [
    "GIROUD A",
    "TUCHMANN-DUPLESSIS H",
    "MERCIER-PAROT L"
   ],
   "journal": "Comptes rendus des seances de la Societe de biologie et de ses filiales",
   "year": "1962",
   "volume": "156",
   "pages": "765-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13956036",
   "doi": "",
   "title": "[On a case of phocomelia probably secondary to maternal influenza virus infection]",
   "authors": [
    "IAFUSCO F",
    "BUFFA V"
   ],
   "journal": "La Pediatria",
   "year": "1962",
   "volume": "70",
   "pages": "954-61",
   "pubtypes": [],
   "codes": [
    "2879"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13948222",
   "doi": "",
   "title": "[Production of congenital malformations in the mouse after administration of weak doses of thalidomide]",
   "authors": [
    "GIROUD A",
    "TUCHMANN-DUPLESSIS H",
    "MERCIER-PAROT L"
   ],
   "journal": "Comptes rendus hebdomadaires des seances de l'Academie des sciences",
   "year": "1962",
   "volume": "255",
   "pages": "1646-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13958747",
   "doi": "",
   "title": "[Responsibility of thalidomide in the etiology of some fetal malformations. On embryopathy caused by chemotherapy]",
   "authors": [
    "FORLEO R"
   ],
   "journal": "Rivista di ostetricia e ginecologia",
   "year": "1962",
   "volume": "17",
   "pages": "518-20",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13957921",
   "doi": "",
   "title": "[Thalidomide and embryopathies. Report of 2 cases]",
   "authors": [
    "JOKI T",
    "VAANANEN I"
   ],
   "journal": "Duodecim; laaketieteellinen aikakauskirja",
   "year": "1962",
   "volume": "78",
   "pages": "822-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "24546678",
   "doi": "",
   "title": "[Thalidomide and malformations. Contribution to the problem of the etiology of a frequently occurring malformation complex]",
   "authors": [
    "PETERSEN CE"
   ],
   "journal": "Die Medizinische Welt",
   "year": "1962",
   "volume": "14",
   "pages": "753-6",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13973102",
   "doi": "",
   "title": "[Thalidomide and malformations]",
   "authors": [
    "RAPOLA J"
   ],
   "journal": "Duodecim; laaketieteellinen aikakauskirja",
   "year": "1962",
   "volume": "78",
   "pages": "819-21",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14005601",
   "doi": "10.1055/s-0028-1111856",
   "title": "[Thalidomide embryopathy. I. Incidence inside and outside Germany]",
   "authors": [
    "WEICKER H",
    "HUNGERLAND H"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1962",
   "volume": "87",
   "pages": "992-8 passim",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "epidemiology"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14005597",
   "doi": "10.1055/s-0028-1113990",
   "title": "[Thalidomide embryopathy. II. Results of individual anamnestic findings in the areas of inquiry of the universities of Bonn, Cologne, Muenster and Duesseldorf pediatric clinics]",
   "authors": [
    "WEICKER H",
    "BACHMANN KD",
    "PFEIFFER RA",
    "et al."
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1962",
   "volume": "87",
   "pages": "1597-607",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13867809",
   "doi": "",
   "title": "[Thalidomide embryopathy]",
   "authors": [
    "BERGSTROM AL",
    "NILSSON L",
    "PETTERSSON G",
    "et al."
   ],
   "journal": "Svenska lakartidningen",
   "year": "1962",
   "volume": "59",
   "pages": "1012-22",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13944387",
   "doi": "",
   "title": "[Thalidomide embryopathy]",
   "authors": [
    "FARIZON F",
    "MASBERNARD A"
   ],
   "journal": "La Presse medicale",
   "year": "1962",
   "volume": "70",
   "pages": "2053-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14455137",
   "doi": "",
   "title": "[Thalidomide embryopathy]",
   "authors": [
    "KENEZ J"
   ],
   "journal": "Orvosi hetilap",
   "year": "1962",
   "volume": "103",
   "pages": "1566-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14464041",
   "doi": "10.1055/s-0028-1111892",
   "title": "[Thalidomide embryopathy]",
   "authors": [
    "LENZ W",
    "KNAPP K"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1962",
   "volume": "87",
   "pages": "1232-42",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13859774",
   "doi": "",
   "title": "[Thalidomide: a teratogenic drug?]",
   "authors": [
    "AIAZZI MANCINI M"
   ],
   "journal": "La Riforma medica",
   "year": "1962",
   "volume": "76",
   "pages": "705-7",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13739079",
   "doi": "10.1055/s-0028-1112880",
   "title": "[Does thalidomide (contergan) cause injurious effects?]",
   "authors": [
    "RAFFAUF HJ"
   ],
   "journal": "Deutsche medizinische Wochenschrift (1946)",
   "year": "1961",
   "volume": "86",
   "pages": "935-8",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "14449940",
   "doi": "",
   "title": "[Nil nocere. Thalidomide (Contergan) polyneuritis]",
   "authors": [
    "HULTSCH EG",
    "HARTMANN J"
   ],
   "journal": "Munchener medizinische Wochenschrift (1950)",
   "year": "1961",
   "volume": "103",
   "pages": "2141-4",
   "pubtypes": [],
   "codes": [
    "thal"
   ],
   "topics": [
    "clinical"
   ],
   "notes": [
    "PubMed title search on thalidomide embryopathy"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "13189284",
   "doi": "10.1111/j.1749-6632.1954.tb36423.x",
   "title": "Wright's studies of effects of maternal age on spotting and polydactyly in the guinea pig",
   "authors": [
    "FOSTER M"
   ],
   "journal": "Annals of the New York Academy of Sciences",
   "year": "1954",
   "volume": "57",
   "pages": "491-3",
   "pubtypes": [],
   "codes": [
    "2913"
   ],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  },
  {
   "pmid": "18140519",
   "doi": "",
   "title": "[Clinical Study of hemimelia; special reference to the etiology of congenital defects]",
   "authors": [
    "DELASCIO D",
    "DELLIVENERI A",
    "AMARAL VT"
   ],
   "journal": "Revista de ginecologia e d'obstetricia",
   "year": "1949",
   "volume": "43",
   "pages": "427-51",
   "pubtypes": [],
   "codes": [],
   "topics": [
    "causes",
    "clinical"
   ],
   "notes": [
    "PubMed search for causes and risk factors of the site's conditions"
   ],
   "via": [
    "PubMed search"
   ]
  }
 ],
 "causes_query": "(\"limb reduction\"[tiab] OR \"limb deficiency\"[tiab] OR \"limb deficiencies\"[tiab] OR \"limb defects\"[tiab] OR \"limb malformations\"[tiab] OR amelia[tiab] OR phocomelia[tiab] OR hemimelia[tiab] OR ectrodactyly[tiab] OR polydactyly[tiab] OR syndactyly[tiab] OR symbrachydactyly[tiab] OR \"Poland syndrome\"[tiab] OR \"amniotic band\"[tiab] OR \"transverse limb\"[tiab]) AND (etiology[ti] OR aetiology[ti] OR causes[ti] OR \"risk factor\"[ti] OR \"risk factors\"[ti] OR teratogen*[ti] OR maternal[ti] OR exposure[ti] OR environmental[ti] OR pesticide*[ti] OR cluster*[ti] OR \"vascular disruption\"[ti]) NOT thalidomide[ti]"
}